Búsqueda | Portal de Búsqueda de la BVS

1.

Nucleation of a key beta-turn promotes cyclotide oxidative folding.

Tian, Sixin; de Veer, Simon J; Durek, Thomas; Wang, Conan K; Craik, David J.

J Biol Chem ; 300(4): 107125, 2024 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-38432638

2.

Enzymatic C-to-C Protein Ligation.

Rehm, Fabian B H; Tyler, Tristan J; de Veer, Simon J; Craik, David J; Durek, Thomas.

Angew Chem Int Ed Engl ; 61(11): e202116672, 2022 03 07.

Artículo en Inglés | MEDLINE | ID: mdl-35018698

3.

Cystine Knot Peptides with Tuneable Activity and Mechanism.

Li, Choi Yi; Rehm, Fabian B H; Yap, Kuok; Zdenek, Christina N; Harding, Maxim D; Fry, Bryan G; Durek, Thomas; Craik, David J; de Veer, Simon J.

Angew Chem Int Ed Engl ; 61(19): e202200951, 2022 05 02.

Artículo en Inglés | MEDLINE | ID: mdl-35224831

4.

Enzymatic C-Terminal Protein Engineering with Amines.

Rehm, Fabian B H; Tyler, Tristan J; Yap, Kuok; de Veer, Simon J; Craik, David J; Durek, Thomas.

J Am Chem Soc ; 143(46): 19498-19504, 2021 11 24.

Artículo en Inglés | MEDLINE | ID: mdl-34761936

5.

An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human ß-Factor XIIa in a Cyclotide Scaffold.

Liu, Wenyu; de Veer, Simon J; Huang, Yen-Hua; Sengoku, Toru; Okada, Chikako; Ogata, Kazuhiro; Zdenek, Christina N; Fry, Bryan G; Swedberg, Joakim E; Passioura, Toby; Craik, David J; Suga, Hiroaki.

J Am Chem Soc ; 143(44): 18481-18489, 2021 11 10.

Artículo en Inglés | MEDLINE | ID: mdl-34723512

6.

Cyclotides: From Structure to Function.

de Veer, Simon J; Kan, Meng-Wei; Craik, David J.

Chem Rev ; 119(24): 12375-12421, 2019 12 26.

Artículo en Inglés | MEDLINE | ID: mdl-31829013

7.

Sunflower Trypsin Inhibitor-1 (SFTI-1): Sowing Seeds in the Fields of Chemistry and Biology.

de Veer, Simon J; White, Andrew M; Craik, David J.

Angew Chem Int Ed Engl ; 60(15): 8050-8071, 2021 04 06.

Artículo en Inglés | MEDLINE | ID: mdl-32621554

8.

Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides.

White, Andrew M; de Veer, Simon J; Wu, Guojie; Harvey, Peta J; Yap, Kuok; King, Gordon J; Swedberg, Joakim E; Wang, Conan K; Law, Ruby H P; Durek, Thomas; Craik, David J.

Angew Chem Int Ed Engl ; 59(28): 11273-11277, 2020 07 06.

Artículo en Inglés | MEDLINE | ID: mdl-32270580

9.

KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.

Riley, Blake T; Ilyichova, Olga; de Veer, Simon J; Swedberg, Joakim E; Wilson, Emily; Hoke, David E; Harris, Jonathan M; Buckle, Ashley M.

Biochemistry ; 58(21): 2524-2533, 2019 05 28.

Artículo en Inglés | MEDLINE | ID: mdl-31058493

10.

Characterising the Subsite Specificity of Urokinase-Type Plasminogen Activator and Tissue-Type Plasminogen Activator using a Sequence-Defined Peptide Aldehyde Library.

Li, Choi Yi; de Veer, Simon J; Law, Ruby H P; Whisstock, James C; Craik, David J; Swedberg, Joakim E.

Chembiochem ; 20(1): 46-50, 2019 01 02.

Artículo en Inglés | MEDLINE | ID: mdl-30225958

11.

Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs.

Magnen, Mélia; Gueugnon, Fabien; Guillon, Antoine; Baranek, Thomas; Thibault, Virginie C; Petit-Courty, Agnès; de Veer, Simon J; Harris, Jonathan; Humbles, Alison A; Si-Tahar, Mustapha; Courty, Yves.

J Virol ; 91(16)2017 08 15.

Artículo en Inglés | MEDLINE | ID: mdl-28615200

12.

Cyclotides as Tools in Chemical Biology.

de Veer, Simon J; Weidmann, Joachim; Craik, David J.

Acc Chem Res ; 50(7): 1557-1565, 2017 07 18.

Artículo en Inglés | MEDLINE | ID: mdl-28644007

13.

Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors.

de Veer, Simon J; Swedberg, Joakim E; Brattsand, Maria; Clements, Judith A; Harris, Jonathan M.

Biol Chem ; 397(12): 1237-1249, 2016 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-26894578

14.

Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.

de Veer, Simon J; Swedberg, Joakim E; Akcan, Muharrem; Rosengren, K Johan; Brattsand, Maria; Craik, David J; Harris, Jonathan M.

Biochem J ; 469(2): 243-53, 2015 Jul 15.

Artículo en Inglés | MEDLINE | ID: mdl-25981970

15.

Tertiary amide bond formation by an engineered asparaginyl ligase.

de Veer, Simon J; Zhou, Yan; Durek, Thomas; Craik, David J; Rehm, Fabian B H.

Chem Sci ; 15(14): 5248-5255, 2024 Apr 03.

Artículo en Inglés | MEDLINE | ID: mdl-38577369

16.

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

de Veer, Simon J; Ukolova, Svetlana S; Munro, Christopher A; Swedberg, Joakim E; Buckle, Ashley M; Harris, Jonathan M.

Biopolymers ; 2013 Mar 11.

Artículo en Inglés | MEDLINE | ID: mdl-23494567

17.

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

de Veer, Simon J; Ukolova, Svetlana S; Munro, Christopher A; Swedberg, Joakim E; Buckle, Ashley M; Harris, Jonathan M.

Biopolymers ; 100(5): 510-8, 2013 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-24078181

18.

Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.

de Veer, Simon J; Swedberg, Joakim E; Parker, Edward A; Harris, Jonathan M.

Biol Chem ; 393(5): 331-41, 2012 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-22505516

19.

Engineering the Cyclization Loop of MCoTI-II Generates Targeted Cyclotides that Potently Inhibit Factor XIIa.

Tian, Sixin; Durek, Thomas; Wang, Conan K; Zdenek, Christina N; Fry, Bryan G; Craik, David J; de Veer, Simon J.

J Med Chem ; 65(23): 15698-15709, 2022 12 08.

Artículo en Inglés | MEDLINE | ID: mdl-36383928

20.

Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system.

Wu, Yue; Cui, Zhenling; Huang, Yen-Hua; de Veer, Simon J; Aralov, Andrey V; Guo, Zhong; Moradi, Shayli V; Hinton, Alexandra O; Deuis, Jennifer R; Guo, Shaodong; Chen, Kai-En; Collins, Brett M; Vetter, Irina; Herzig, Volker; Jones, Alun; Cooper, Matthew A; King, Glenn F; Craik, David J; Alexandrov, Kirill; Mureev, Sergey.

Nat Commun ; 13(1): 260, 2022 01 11.

Artículo en Inglés | MEDLINE | ID: mdl-35017494

Portal de Búsqueda de la BVS

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar:

Nucleation of a key beta-turn promotes cyclotide oxidative folding.

Enzymatic C-to-C Protein Ligation.

Cystine Knot Peptides with Tuneable Activity and Mechanism.

Enzymatic C-Terminal Protein Engineering with Amines.

An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human ß-Factor XIIa in a Cyclotide Scaffold.

Cyclotides: From Structure to Function.

Sunflower Trypsin Inhibitor-1 (SFTI-1): Sowing Seeds in the Fields of Chemistry and Biology.

Application and Structural Analysis of Triazole-Bridged Disulfide Mimetics in Cyclic Peptides.

KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.

Characterising the Subsite Specificity of Urokinase-Type Plasminogen Activator and Tissue-Type Plasminogen Activator using a Sequence-Defined Peptide Aldehyde Library.

Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs.

Cyclotides as Tools in Chemical Biology.

Exploring the active site binding specificity of kallikrein-related peptidase 5 (KLK5) guides the design of new peptide substrates and inhibitors.

Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition.

Tertiary amide bond formation by an engineered asparaginyl ligase.

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1.

Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.

Engineering the Cyclization Loop of MCoTI-II Generates Targeted Cyclotides that Potently Inhibit Factor XIIa.

Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system.