A reconfigurable, wearable, wireless ECG system.

New emerging concepts as "wireless hospital", "mobile healthcare" or "wearable telemonitoring" require the development of bio-signal acquisition devices to be easily integrated into the clinical routine. In this work, we present a new system for Electrocardiogram (ECG) acquisition and its processing, with wireless transmission on demand (either the complete ECG or only one alarm message, just in case a pathological heart rate detected). Size and power consumption are optimized in order to provide mobility and comfort to the patient. We have designed a modular hardware system and an autonomous platform based on a Field-Programmable Gate Array (FPGA) for developing and debugging. The modular approach allows to redesign the system in an easy way. Its adaptation to a new biomedical signal would only need small changes on it. The hardware system is composed of three layers that can be plugged/unplugged: communication layer, processing layer and sensor layer. In addition, we also present a general purpose end-user application developed for mobile phones or Personal Digital Assistant devices (PDAs).

[Cytomegalovirus colitis simulating neoplasm in a patient with HIV infection]. / Colitis por citomegalovirus que simula una neoplasia en paciente con infección por HIV.

AIM: Cytomegalovirus colitis occurs in at least 5-10% of patients with AIDS. The most usual form of clinical presentation is that of a chronic picture of diarrhea, fever and abdominal pain in a patient with AIDS with a CD4 lymphocyte count lower than 100/mm3, although it can be the diagnostic index for AIDS up to in 25% of the cases. METHODS: Cytomegalovirus colitis in a patient with AIDS was diagnosed by endoscopy and colonic biopsy. The clinical was diagnosed by endoscopy and colonic biopsy. The clinical picture consisted of abdominal pain, without the findings of fever and diarrhea described in almost 80% and 100% respectively of the cases published in the literature. The barium enema carried out showed a stenotic appearance, like serviette ring, in the ascending colon, which suggested neoplasia of the colon. RESULTS: Induction therapy with ganciclovir was effective. However, the patient was readmitted one year later for chorioretinitis due to cytomegalovirus, without any evidence of gastro-intestinal involvement. CONCLUSIONS: Although unusual, cytomegalovirus colitis can be present with an abdominal clinical picture without diarrhea. Radiological and/or endoscopic pseudotumoral forms which this entity can adopt are often described. Endoscopy with digestive biopsy in essential for diagnosis. Therapy with ganciclovir can be effective although the reappearance of findings from cytomegalovirus can occur at another area, or as a gastrointestinal recurrence.