1.
CMAJ
; 191(10): E286, 2019 03 11.
Artículo
en Inglés
| MEDLINE
| ID: mdl-30858185
Asunto(s)
Glucagón/sangre , Glucagonoma/etiología , Eritema Necrolítico Migratorio/etiología , Anciano , Glucagonoma/sangre , Glucagonoma/diagnóstico por imagen , Glucagonoma/terapia , Humanos , Masculino , Eritema Necrolítico Migratorio/sangre , Eritema Necrolítico Migratorio/terapia , Neoplasias Pancreáticas/sangre , Neoplasias Pancreáticas/diagnóstico por imagen , Tomografía Computarizada por Rayos X
2.
J Gen Intern Med
; 28(11): 1525-9, 2013 Nov.
Artículo
en Inglés
| MEDLINE
| ID: mdl-23681843
RESUMEN
Glucagonomas are slow-growing, rare pancreatic neuroendocrine tumors. They may present with paraneoplastic phenomena known together as the "glucagonoma syndrome." A hallmark sign of this syndrome is a rash known as necrolytic migratory erythema (NME). In this paper, the authors describe a patient with NME and other features of the glucagonoma syndrome. The diagnosis of this rare tumor requires an elevated serum glucagon level and imaging confirming a pancreatic tumor. Surgical and medical treatment options are reviewed. When detected early, a glucagonoma is surgically curable. It is therefore imperative that clinicians recognize the glucagonoma syndrome in order to make an accurate diagnosis and refer for treatment.