Detalhe da pesquisa
1.
Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate.
Biochem J
; 477(21): 4263-4280, 2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33057580
2.
Metastable HIV-1 Surface Protein Env Sensitizes Cell Membranes to Transformation and Poration by Dual-Acting Virucidal Entry Inhibitors.
Biochemistry
; 59(6): 818-828, 2020 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31942789
3.
Restricted HIV-1 Env glycan engagement by lectin-reengineered DAVEI protein chimera is sufficient for lytic inactivation of the virus.
Biochem J
; 475(5): 931-957, 2018 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29343613
4.
Recognition of HIV-inactivating peptide triazoles by the recombinant soluble Env trimer, BG505 SOSIP.664.
Proteins
; 85(5): 843-851, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28056499
5.
Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring.
Org Biomol Chem
; 15(37): 7770-7782, 2017 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28770939
6.
Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer.
Biochemistry
; 55(44): 6100-6114, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27731975
7.
Computational Evaluation of HIV-1 gp120 Conformations of Soluble Trimeric gp140 Structures as Targets for de Novo Docking of First- and Second-Generation Small-Molecule CD4 Mimics.
J Chem Inf Model
; 56(10): 2069-2079, 2016 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27602436
8.
Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 Envelope gp120 and the Host-Cell CCR5 Coreceptor at the Virus-Cell Interface.
J Med Chem
; 61(11): 5020-5033, 2018 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29767965