Detalhe da pesquisa
1.
Chirality matters: stereo-defined phosphorothioate linkages at the termini of small interfering RNAs improve pharmacology in vivo.
Nucleic Acids Res
; 50(3): 1221-1240, 2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34268578
2.
siRNAs containing 2'-fluorinated Northern-methanocarbacyclic (2'-F-NMC) nucleotides: in vitro and in vivo RNAi activity and inability of mitochondrial polymerases to incorporate 2'-F-NMC NTPs.
Nucleic Acids Res
; 49(5): 2435-2449, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33577685
3.
Kinetic study of the binding of triplex-forming oligonucleotides containing partial cationic modifications to double-stranded DNA.
Bioorg Med Chem Lett
; 24(14): 3046-9, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24865415
4.
Synthesis of oligonucleotides containing N,N-disubstituted 3-deazacytosine nucleobases by post-elongation modification and their triplex-forming ability with double-stranded DNA.
Org Biomol Chem
; 12(44): 9011-5, 2014 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25285418
5.
Synthesis and Biophysical Properties of Phosphorodiamidate Piperidino Oligomers.
Org Lett
; 25(6): 901-906, 2023 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36734846
6.
RNAs Containing Carbocyclic Ribonucleotides.
Org Lett
; 24(2): 525-530, 2022 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34958225
7.
Synthesis of 2'-Fluorinated Northern Methanocarbacyclic (2'-F-NMC) Nucleosides and Their Incorporation Into Oligonucleotides.
Curr Protoc Nucleic Acid Chem
; 80(1): e103, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31985895
8.
Synthesis and Biophysical Characterization of RNAs Containing 2'-Fluorinated Northern Methanocarbacyclic Nucleotides.
Org Lett
; 21(7): 1963-1967, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30892051
9.
Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the ß-Lactam Antibiotics.
ACS Infect Dis
; 4(6): 860-867, 2018 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29716193