Detalhe da pesquisa
1.
Genome-wide analysis of mammalian promoter architecture and evolution.
Nat Genet
; 38(6): 626-35, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16645617
2.
Saturation mutagenesis reveals the importance of residues alphaR145 and alphaF146 of penicillin acylase in the synthesis of beta-lactam antibiotics.
J Biotechnol
; 133(1): 18-26, 2008 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17933411
3.
MSCAN: identification of functional clusters of transcription factor binding sites.
Nucleic Acids Res
; 32(Web Server issue): W195-8, 2004 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15215379
4.
Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase.
Protein Eng Des Sel
; 17(5): 473-80, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15254299
5.
Regulog analysis: detection of conserved regulatory networks across bacteria: application to Staphylococcus aureus.
Genome Res
; 14(7): 1362-73, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15231752
6.
The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase.
Eur J Biochem
; 269(8): 2093-100, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11985586
7.
Quantifying the accessibility of the metagenome by random expression cloning techniques.
Environ Microbiol
; 6(9): 879-86, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15305913
8.
Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics.
Eur J Biochem
; 270(18): 3675-83, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12950251
9.
Role of alphaArg145 and betaArg263 in the active site of penicillin acylase of Escherichia coli.
Biochem J
; 365(Pt 1): 303-9, 2002 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12071857