Do Orthopaedic Oncologists Agree on the Diagnosis and Treatment of Cartilage Tumors of the Appendicular Skeleton?

BACKGROUND: Distinguishing a benign enchondroma from a low-grade chondrosarcoma is a common diagnostic challenge for orthopaedic oncologists. Low interrater agreement has been observed for the diagnosis of cartilaginous neoplasms among radiologists and pathologists, but, to our knowledge, no study has evaluated inter- and intraobserver agreement among orthopaedic oncologists grading these lesions using initial clinical and imaging information. Determining such agreement is important since it reflects the certainty in the diagnosis by orthopaedic oncologists. Agreement also is important as it will guide future treatment and prognosis, considering that there is no gold standard for diagnosis of these lesions. QUESTIONS/PURPOSES: (1) to determine inter- and intraobserver agreement among a multinational panel of expert orthopaedic oncologists in diagnosing cartilaginous neoplasms based on their assessment of clinical symptoms and imaging at diagnosis. (2) To describe the most important clinical and imaging features that experts use during the initial diagnostic process. (3) To determine interobserver agreement for proposed initial treatment strategies for cartilaginous neoplasms by this panel of evaluators. METHODS: Thirty-nine patients with intramedullary cartilaginous neoplasms of the appendicular skeleton of various histopathologic grades were selected and classified as having benign, low-grade malignant, or intermediate- or high-grade malignant neoplasms by 10 experienced orthopaedic oncologists based on clinical and imaging information. Additionally, they chose the three most important clinical or imaging features for the diagnosis of these neoplasms, and they proposed a treatment strategy for each patient. The Kappa coefficient (κ) was used to determine inter- and intraobserver agreement. RESULTS: Inter- and intraobserver agreements were only fair to good, κ = 0.44(95% CI, 0.41-0.48) and κ = 0.62 (95% CI, 0.52-0.72), respectively. The three factors most frequently identified as helpful in making the diagnosis by our panel were cortical involvement in 65% of evaluations (253/390), neoplasm size in 51% (198/390), and pain in 50% (194/390). The interobserver agreement for the proposed initial treatment strategy after diagnosis was poor (κ = 0.21; 95% CI, 0.18-0.24). CONCLUSIONS: This study showed barely fair interobserver and fair to good intraobserver agreement for grading of intramedullary cartilaginous neoplasms by orthopaedic oncologists using initial clinical and imaging findings. These results reflect the insufficient guidance interpreting clinical and imaging features, and the limitations of the systems we use today when making these diagnoses. In the same way, they generate concern for the implications that this may have on different treatment strategies and the future prognosis of our patients. Future studies should build on these observations and focus on clarifying our criteria of diagnosis so that treatment recommendations are standardized regardless of the treating institution or oncologist. LEVEL OF EVIDENCE: Level III, diagnostic study.

[Perioperative care of older patients with hip fractures]. / Optimización perioperatoria del paciente anciano con fractura osteoporótica de cadera.

The number of osteoporotic fractures is increasing along with population aging. Most patients with these type of fractures are older than 65 years, with multiple chronic conditions and different degrees of disability. Hip fracture is the most relevant osteoporotic fracture due to its frequency, costs, severity and complications. Multidisciplinary management is of the utmost importance to obtain good therapeutic results. We herein review the management of this fracture. Orthogeriatric joint management should be incorporated in fragility fracture treatment. We contribute with general recommendations for the perioperative management, which can be homologated for the management of older patients with other type of fragility fractures.

[Vitamin D levels among Chilean older subjects with low energy hip fracture]. / Prevalencia de insuficiencia y deficiencia de vitamina D en adultos mayores con fractura de cadera en Chile.

BACKGROUND: Vitamin D deficiency is a common condition affecting 40-100% of geriatric population. AIM: To determine the prevalence of vitamin D insufficiency and deficiency in geriatric population surgically treated for hip fracture. PATIENTS AND METHODS: Analysis of a database of patients aged over 60 years operated for a low energy hip fracture in a three years period. Vitamin D was measured in identified patients, using a blood sample obtained on admission to the hospital. A logistic regression was carried out to evaluate age, gender, morbidity index and season as predictors of vitamin D deficiency. RESULTS: Two hundred and twenty-eight patients aged 84 ± 7 years (82% females), were included in the analysis. One hundred eighty-three patients (80%) presented vitamin D levels below 20 ng/dl (deficiency) and 39 patients (18%) presented with levels between 20 and 30 ng/dl (insufficiency), totaling 98% of patients with hypovitaminosis D. Vitamin D deficiency was especially common among patients with higher American Society of Anesthesiologists (ASA) Physical Status Classification System and during winter-spring period. A negative correlation between age and the proportion of subjects with vitamin D deficiency was found. There was no relation between gender and vitamin D levels. CONCLUSIONS: Vitamin D deficiency is especially prevalent in older subjects with hip fracture, reaching 98% in the studied population.

Surgical dislocation of the hip without trochanteric osteotomy.

BACKGROUND: Surgical dislocation of the hip remains an important alternative in hip preservation surgery, especially when a dynamic access to the hip is needed and arthroscopy is not a suitable option. We describe a novel technique for operative dislocation of the hip without trochanteric osteotomy and the clinical results of our patients. METHODS: Surgical dislocation of the hip without trochanteric osteotomy was done through a modified lateral approach in all of the cases. A review of demographic, clinical, and radiological data was done in all of the patients operated with this technique between 2010 and 2015. Complications, walking aids, weight-bearing status, and modified Harris Hip Score (mHHS) were also recorded. RESULTS: Six surgical dislocations of the hip were carried out. Indications were tumor resection in five and bulletectomy in one hip. There were two women (four hips) and two men. Mean age was 19 ± 3.8 years. Median follow-up was 2.5 years (range 2-4.5 years). Median mHHS was 92 (90-96). There were no intraoperative nor postoperative complications. CONCLUSIONS: Surgical dislocation of the hip without trochanteric osteotomy through a modified lateral approach appears to be a safe, simpler, and effective alternative.

Surgical light handles: a source of contamination in the surgical field.

OBJECTIVE: Total hip arthroplasty (THA) is a common and generally safe procedure; however, among the most devastating complications associated with THA is periprosthetic infection (PPI). The origin of bacteria causing PPI is not completely understood. The aims of the present study were to identify bacterial contamination of light handles with up-to-date culture methods and to determine the safety in using these handles in hip arthroplasty surgery. METHODS: A total of 36 surgical handles randomly selected from primary hip arthroplasty procedures were screened for bacterial contamination using 2 different culture methods, including 1 with high sensitivity. Two types of controls were used. Cultures were kept for up to 10 days, and retrieved bacteria were identified. RESULTS: Fifty percent of the light handles yielded positive cultures, demonstrating a bacterial presence on surgical light handles during hip arthroplasty. The most frequently identified bacteria were Staphylococcus epidermidis and Staphylococcus aureus. CONCLUSION: A large number of positive bacterial cultures were found in manipulated light handles during hip replacement surgery, representing a potential contamination source that could eventually lead to infection in hip arthroplasty.

Optimización perioperatoria del paciente anciano con fractura osteoporótica de cadera / Perioperative care of older patients with hip fractures

The number of osteoporotic fractures is increasing along with population aging. Most patients with these type of fractures are older than 65 years, with multiple chronic conditions and different degrees of disability. Hip fracture is the most relevant osteoporotic fracture due to its frequency, costs, severity and complications. Multidisciplinary management is of the utmost importance to obtain good therapeutic results. We herein review the management of this fracture. Orthogeriatric joint management should be incorporated in fragility fracture treatment. We contribute with general recommendations for the perioperative management, which can be homologated for the management of older patients with other type of fragility fractures.

Prevalencia de insuficiencia y deficiencia de vitamina D en adultos mayores con fractura de cadera en Chile / Vitamin D levels among Chilean older subjects with low energy hip fracture

Background: Vitamin D deficiency is a common condition affecting 40-100% of geriatric population. Aim: To determine the prevalence of vitamin D insufficiency and deficiency in geriatric population surgically treated for hip fracture. Patients and Methods: Analysis of a database of patients aged over 60 years operated for a low energy hip fracture in a three years period. Vitamin D was measured in identified patients, using a blood sample obtained on admission to the hospital. A logistic regression was carried out to evaluate age, gender, morbidity index and season as predictors of vitamin D deficiency. Results: Two hundred and twenty-eight patients aged 84 ± 7 years (82% females), were included in the analysis. One hundred eighty-three patients (80%) presented vitamin D levels below 20 ng/dl (deficiency) and 39 patients (18%) presented with levels between 20 and 30 ng/dl (insufficiency), totaling 98% of patients with hypovitaminosis D. Vitamin D deficiency was especially common among patients with higher American Society of Anesthesiologists (ASA) Physical Status Classification System and during winter-spring period. A negative correlation between age and the proportion of subjects with vitamin D deficiency was found. There was no relation between gender and vitamin D levels. Conclusions: Vitamin D deficiency is especially prevalent in older subjects with hip fracture, reaching 98% in the studied population.

[Total knee arthroplasty in patients with rheumatoid arthritis]. / Artroplastia total de rodilla en pacientes con artritis reumatoide.

BACKGROUND: Approximately 90% of patients with rheumatoid arthritis (RA) will have one or both knees involved during the course of the disease. Total knee arthroplasty (TKA) allows restoring function and relieving pain satisfactorily, but these patients perform in a different way than those with primary knee osteoarthritis. AIM: To evaluate the clinical and radiographic results of TKA in patients with RA. PATIENTS AND METHODS: We analyzed retrospectively the data of 25 posterior stabilized total knee prostheses in 19 patients, available to an average follow-up of 6 years. The scores of Hospital for Special Surgery and of the Knee Society were used for clinical assessment. RESULTS: The mean Hospital for Special Surgery score increased from 44 points (range 27-58) preoperatively to 80 points (range 58-91) at the final follow-up examination. Two prostheses required revision and removal of the implants because of deep infection, and two had clinical failure as defined by the Knee Society score. There were no cases of implant loosening. DISCUSSION: Even though it is not free of complications, TKA is a good choice in patients with RA in the medium term follow up, with 80% of excellent and good results in our series.

[Bone marrow edema syndrome of the hip]. / Síndrome de edema de la médula ósea de cadera.

BACKGROUND: Bone marrow edema syndrome (BMES) is a rare clinical condition. Its etiology is unknown and it can be seen in different locations. In the case of the hip, avascular necrosis is the main differential diagnosis. AIM: To present our experience of BMES of the hip and a review of the literature. PATIENTS AND METHODS: Retrospective analysis of clinical records of patients with hip pain that met clinical, radiological, and magnetic resonance imaging criteria for BMES. Clinical outcome and clinical and radiological follow up are presented. RESULTS: Two men and two women (one of them pregnant) aged 42, 48, 36 and 26 years old, fulfilled criteria. Treatment included limited weight bearing, non steroidal antiinflammatory drugs, intranasal calcitonin and physical therapy. Complete remission of symptoms was observed within five to seven months. At an average follow up of 36 months, all patients presented complete function of the hip, returning to their previous activity levels, with no new episodes of BMES. CONCLUSIONS: It is important to be aware of this condition as part of the differential diagnosis of hip pain to avoid aggressive and unnecessary diagnostic and therapeutic procedures.