Impact of workflow-integrated corollary orders on aminoglycoside monitoring in children.

Computerized provider order entry (CPOE) and clinical decision support improve medication prescribing safety in adults. However, effective therapy for children requires dosing based on circulating medication levels. We examined the introduction of a computerized corollary order for aminoglycoside blood level monitoring. The study was divided into baseline (BP) and corollary order (CP) periods. In the CP, we implemented a workflow-integrated reminder to order blood levels and presented this to the clinician during each aminoglycoside ordering session. Appropriate laboratory monitoring was 128/159 (80.5%) courses in the BP and 146/177 (82.5%) courses in the CP. Thus introduction of the order did not significantly improve laboratory monitoring rates, nor did it result in a reduction in the rate of either toxic or subtherapeutic levels. However, aminoglycoside corollary orders may have an important role in institutions where pharmacists are not actively involved in monitoring therapy.

Inpatient verbal orders and the impact of computerized provider order entry.

OBJECTIVE: To describe the characteristics of verbal orders at a tertiary care children's hospital. STUDY DESIGN: Between August 2003 and January 2004, the computerized provider order entry (CPOE) system was evaluated for the characteristics of verbal orders. The rate of total orders represented by verbal orders and the rate of unsigned verbal orders were examined before, during, and after CPOE implementation. RESULTS: After CPOE implementation, a mean of 19,996 +/- 521 orders were generated weekly; of these, 2094 +/- 65 (10%) were verbal orders. The greatest rates of verbal orders were from psychiatry (74%) units and involved medication orders (38%; 790/2094). The greatest rates of medication verbal orders were psychotherapeutics (24%; 662/2697). Medical physicians had a larger rate of verbal orders than surgical physicians. The rates of verbal orders and unsigned verbal orders were reduced from 23% and 43% before CPOE implementation to 10% and 9% after implementation, respectively. CONCLUSIONS: Medication orders from physicians to nurses are the primary source of verbal orders in this tertiary care children's hospital. CPOE implementation significantly affected both verbal orders and the rate of unsigned verbal orders. This type of data is important for institutions aiming to decrease verbal orders and associated medical errors.