Detalhe da pesquisa
1.
DAXX safeguards heterochromatin formation in embryonic stem cells.
J Cell Sci
; 136(19)2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37655670
2.
A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation.
Nucleic Acids Res
; 51(19): 10292-10308, 2023 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37650637
3.
Advances in Chemical Probing Concepts for Chemical Biology Applications.
Chembiochem
; 24(17): e202300319, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37501334
4.
EFMC: Trends in Medicinal Chemistry and Chemical Biology.
Chembiochem
; 24(7): e202200690, 2023 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36704975
5.
PSL Chemical Biology Symposia Third Edition: A Branch of Science in its Explosive Phase.
Chembiochem
; 24(8): e202300093, 2023 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36942862
6.
Inhibitors of DNA Methylation.
Adv Exp Med Biol
; 1389: 471-513, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36350520
7.
Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein.
Molecules
; 26(17)2021 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34500733
8.
The DNMT3A R882H mutant displays altered flanking sequence preferences.
Nucleic Acids Res
; 46(6): 3130-3139, 2018 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29518238
9.
Assembly of the Entire Carbon Backbone of a Stereoisomer of the Antitumor Marine Natural Product Hemicalide.
Chemistry
; 25(11): 2745-2749, 2019 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30600846
10.
Natural Products and Chemical Biology Tools: Alternatives to Target Epigenetic Mechanisms in Cancers.
Chem Rec
; 18(12): 1854-1876, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30537358
11.
Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches.
J Comput Aided Mol Des
; 32(3): 435-458, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29335872
12.
New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors.
J Biol Chem
; 290(10): 6293-302, 2015 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25525263
13.
Identification of epigenetic factors regulating the mesenchyme to epithelium transition by RNA interference screening in breast cancer cells.
BMC Cancer
; 16: 700, 2016 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-27581651
14.
DNA Methyltransferase Inhibitors: Development and Applications.
Adv Exp Med Biol
; 945: 431-473, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27826847
15.
Design and synthesis of new non nucleoside inhibitors of DNMT3A.
Bioorg Med Chem
; 23(17): 5946-53, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26220519
16.
Development of a universal radioactive DNA methyltransferase inhibition test for high-throughput screening and mechanistic studies.
Nucleic Acids Res
; 41(19): e185, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23980028
17.
DNA methylation associated with polycomb repression in retinoic acid receptor ß silencing.
FASEB J
; 27(4): 1468-78, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23299856
18.
Correction: Zwergel et al. Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation. Cancers 2020, 12, 447.
Cancers (Basel)
; 16(6)2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38539577
19.
Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells.
Nat Commun
; 15(1): 2960, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38580649
20.
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization.
J Cell Biol
; 223(4)2024 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38376465