Detalhe da pesquisa
1.
Clinical Pharmacology of RNA Interference-Based Therapeutics: A Summary Based on Food and Drug Administration-Approved Small Interfering RNAs.
Drug Metab Dispos
; 51(2): 193-198, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36332914
2.
Innovations, Opportunities, and Challenges for Predicting Alteration in Drug-Metabolizing Enzyme and Transporter Activity in Specific Populations.
Drug Metab Dispos
; 51(12): 1547-1550, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37775331
3.
Long-Acting Formulations for the Prevention and Treatment of Human Immunodeficiency Virus (HIV)-1 Infection: Strategic Leveraging and Integration of Multidisciplinary Knowledge to Advance Public Health.
Clin Infect Dis
; 75(Suppl 4): S498-S501, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36410378
4.
Do differences in cell lines and methods used for calculation of IC50 values influence categorisation of drugs as P-glycoprotein substrates and inhibitors?
Xenobiotica
; 52(7): 751-757, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-36218364
5.
Why did the FDA approve efavirenz 800 mg when co-administered with rifampin?
Int J Clin Pharmacol Ther
; 52(6): 446-53, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24755134
6.
Food-Drug Effects and Pediatric Drug Development Studies Submitted to the US Food and Drug Administration, 2012-2022.
J Clin Pharmacol
; 64(6): 697-703, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38294346
7.
Considerations and Challenges in the Remdesivir COVID-19 Pediatric Development Program.
J Clin Pharmacol
; 63(2): 259-265, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36149807
8.
Using Endogenous Biomarkers to Derisk Assessment of Transporter-Mediated Drug-Drug Interactions: A Scientific Perspective.
J Clin Pharmacol
; 62(12): 1501-1506, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35778968
9.
Whole Body PBPK Modeling of Remdesivir and Its Metabolites to Aid in Estimating Active Metabolite Exposure in the Lung and Liver in Patients With Organ Dysfunction.
Clin Pharmacol Ther
; 111(3): 624-634, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34656075
10.
Considerations and challenges in developing novel long-acting antiretrovirals modalities for treatment and prevention of HIV-1 infection: a regulatory perspective.
Curr Opin HIV AIDS
; 15(1): 61-65, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31483323
11.
Mechanistic Models as Framework for Understanding Biomarker Disposition: Prediction of Creatinine-Drug Interactions.
CPT Pharmacometrics Syst Pharmacol
; 9(5): 282-293, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32410382
12.
A Novel Physiologically Based Model of Creatinine Renal Disposition to Integrate Current Knowledge of Systems Parameters and Clinical Observations.
CPT Pharmacometrics Syst Pharmacol
; 9(6): 310-321, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32441889
13.
A Comprehensive Updated Review on SARS-CoV-2 and COVID-19.
J Clin Pharmacol
; 60(8): 954-975, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32469437
14.
Comparing Various In Vitro Prediction Methods to Assess the Potential of a Drug to Inhibit P-glycoprotein (P-gp) Transporter In Vivo.
J Clin Pharmacol
; 59(8): 1049-1060, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30924955
15.
The Vision for Expanding the Visibility of the Journal of Clinical Pharmacology: Meet the New Editor-in-Chief and the 3 New Associate Editors!
J Clin Pharmacol
; 64(1): 7-9, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38017359
16.
Cobicistat-containing antiretroviral regimens are not recommended during pregnancy: viewpoint.
AIDS
; 33(6): 1089-1093, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30946163
17.
Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium.
Clin Pharmacol Ther
; 104(5): 836-864, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30347454
18.
Laser-ablated nanofunctional polymers for the formulation of slow-release powders for dry powder inhalers: physicochemical characterization and slow-release characteristics.
J Pharm Pharmacol
; 59(11): 1473-84, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17976257
19.
Evaluation of transporters in drug development: Current status and contemporary issues.
Adv Drug Deliv Rev
; 116: 100-118, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28760687
20.
Physiologically Based Pharmacokinetic Modeling for Predicting the Effect of Intrinsic and Extrinsic Factors on Darunavir or Lopinavir Exposure Coadministered With Ritonavir.
J Clin Pharmacol
; 57(10): 1295-1304, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28569994