Detalhe da pesquisa
1.
Design, synthesis, and antitumor efficacy of novel 5-deazaflavin derivatives backed by kinase screening, docking, and ADME studies.
J Enzyme Inhib Med Chem
; 38(1): 2220570, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37341389
2.
Surfactant protein D is a useful biomarker for monitoring acute lung injury in rats.
Exp Lung Res
; 42(6): 314-21, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27541374
3.
The protective effects of ß-cryptoxanthin on inflammatory bone resorption in a mouse experimental model of periodontitis.
Biosci Biotechnol Biochem
; 77(4): 860-2, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23615426
4.
Mechanism of inhibition of HIV-1 reverse transcriptase by 4'-Ethynyl-2-fluoro-2'-deoxyadenosine triphosphate, a translocation-defective reverse transcriptase inhibitor.
J Biol Chem
; 284(51): 35681-91, 2009 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19837673
5.
Synthesis and antiviral evaluation of α-D-2',3'-didehydro-2',3'-dideoxy-3'-C-hydroxymethyl nucleosides.
Bioorg Med Chem Lett
; 20(20): 6013-6, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20833044
6.
Potent activity of a nucleoside reverse transcriptase inhibitor, 4'-ethynyl-2-fluoro-2'-deoxyadenosine, against human immunodeficiency virus type 1 infection in a model using human peripheral blood mononuclear cell-transplanted NOD/SCID Janus kinase 3 knockout mice.
Antimicrob Agents Chemother
; 53(9): 3887-93, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19546363
7.
2'-deoxy-4'-C-ethynyl-2-halo-adenosines active against drug-resistant human immunodeficiency virus type 1 variants.
Int J Biochem Cell Biol
; 40(11): 2410-20, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18487070
8.
Antitumor studies. Part 4: Design, synthesis, antitumor activity, and molecular docking study of novel 2-substituted 2-deoxoflavin-5-oxides, 2-deoxoalloxazine-5-oxides, and their 5-deaza analogs.
Bioorg Med Chem
; 16(2): 922-40, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17962027
9.
Synthesis, biological active molecular design, and molecular docking study of novel deazaflavin-cholestane hybrid compounds.
Bioorg Med Chem
; 16(18): 8685-96, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18723355
10.
Antitumor studies. Part 5: Synthesis, antitumor activity, and molecular docking study of 5-(monosubstituted amino)-2-deoxo-2-phenyl-5-deazaflavins.
Bioorg Med Chem
; 16(20): 9161-70, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18819815
11.
Antithyroid Drugs Inactivate TSH Binding to the TSH Receptor by their Reducing Action.
Endocr Metab Immune Disord Drug Targets
; 18(5): 508-512, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29468987
12.
Enzyme-linked immunosorbent assay for S100A9 in the stool of rats with dextran sulfate sodium-induced colitis.
J Immunol Methods
; 439: 44-49, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693389
13.
Potential of 4'-C-substituted nucleosides for the treatment of HIV-1.
Antivir Chem Chemother
; 15(4): 169-87, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15457679
14.
Attempt to reduce cytotoxicity by synthesizing the L-enantiomer of 4'-C-ethynyl-2'-deoxypurine nucleosides as antiviral agents against HIV and HBV.
Antivir Chem Chemother
; 15(3): 161-7, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15266898
15.
Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides.
Nucleosides Nucleotides Nucleic Acids
; 23(4): 671-90, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15200030
16.
Antitumor studies. part 3: design, synthesis, antitumor activity, and molecular docking study of novel 2-methylthio-, 2-amino-, and 2-(N-substituted amino)-10-alkyl-2-deoxo-5-deazaflavins.
Bioorg Med Chem
; 15(19): 6336-52, 2007 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17644399
17.
Antitumor studies. Part 1: design, synthesis, antitumor activity, and AutoDock study of 2-deoxo-2-phenyl-5-deazaflavins and 2-deoxo-2-phenylflavin-5-oxides as a new class of antitumor agents.
Bioorg Med Chem
; 15(1): 242-56, 2007 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17049252
18.
Synthesis and antiviral activities of 1'-carbon-substituted 4'-thiothymidines.
Bioorg Med Chem
; 12(20): 5309-16, 2004 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15388158