RESUMO
Odontogenic keratocysts (OKCs) are aggressive lesions that have been variously classified as neoplasms or cysts according to the World Health Organisation (WHO). They can be challenging to surgically remove and the cysts can exhibit locally aggressive behaviour if incompletely excised. We describe a case of recurrent OKC invading the orbit requiring multidisciplinary approach for extended surgical excision, and review the current literature regarding this condition.
Assuntos
Cistos Odontogênicos , Tumores Odontogênicos , Humanos , Cistos Odontogênicos/diagnóstico por imagem , Cistos Odontogênicos/patologia , Cistos Odontogênicos/cirurgiaRESUMO
Salivary gland cancers are a complex group of tumours with variations in location, type and grade, all of which influence their biological behaviour. The understanding of salivary gland pathology has evolved at the molecular level in the last decade leading to identification of distinct entities, development of improved methods of diagnosis as well as identifying therapeutic targets for selected high-grade tumours. This article focuses on these advances and their impact on the management of primary salivary gland cancers.
Assuntos
Patologia Molecular/métodos , Neoplasias das Glândulas Salivares/epidemiologia , Neoplasias das Glândulas Salivares/patologia , Biomarcadores Tumorais/metabolismo , Carcinoma Mucoepidermoide/metabolismo , Carcinoma Mucoepidermoide/patologia , Carcinoma Mucoepidermoide/cirurgia , Evolução Molecular , Feminino , Humanos , Masculino , Carcinoma Secretor Análogo ao Mamário/metabolismo , Carcinoma Secretor Análogo ao Mamário/patologia , Carcinoma Secretor Análogo ao Mamário/cirurgia , Neoplasias das Glândulas Salivares/metabolismo , Neoplasias das Glândulas Salivares/cirurgia , Cirurgia Bucal/tendênciasRESUMO
Metastases to the parotid gland are the commonest cause of parotid malignancies in many regions of the world including Australia. The most common etiology of these metastases is head and neck cutaneous squamous cell carcinoma (HNcSCC) followed by melanoma of the head and neck. This article focuses on the management of the aforementioned pathologies including Merkel cell carcinoma (MCC).