Acute necrotizing large vessel arteritis in a newborn: a case report and review of the literature.

Acute arteritis of the aorta and the main pulmonary arteries is unusual in a newborn. This type of vasculitis should be described as a separate entity. There are many differences between this entity and polyarteritis nodosa or Takayasu disease. Moreover, neither Takayasu disease nor polyarteritis nodosa and other forms of classic primary large vessels vasculitis have been reported in a neonate until now. The presence of chronic inflammation, fibrosis, and calcification would suggest that this process had been present before birth.We report a 27-day-old newborn with acute necrotizing aortitis. The feature of this entity is not those of any of the classic entities described in infants or children.

Statistical Analysis of Organ Morphometric Parameters and Weights in South Iranian Adult Autopsies.

Organ weight is one important indicator to discern normal from abnormal condition in forensic pathology as well as in clinical medicine. The present study aimed to investigate morphometric parameters and organ weights of southern Iranian adults, which can be fundamental sources to be compared to abnormal cases.Morphometric parameters and weights of 6 organs (heart, liver, kidney, spleen, appendix, and brain), which were harvested from 501 southern Iranian adults (385 males and 116 females) during ordinary postmortem examination, were measured.All the organs were heavier in males than in females. Heart, brain, spleen, and right kidney were significantly heavier in males compared to females, but no significant difference was observed between the 2 sexes regarding the weights of the rest of the organs. Moreover, brain and heart became heavier as one got older and most organs were heavier in middle-aged individuals compared to other age groups. Furthermore, various types of correlations were observed between different organs' weights and body parameters.These results can be useful anatomical data for autopsy investigations, clinical practices, and research in southern Iran.

Missed opportunities for diagnosis of post-traumatic thrombosis: a case series and literature review.

Thrombosis is caused by abnormalities in the composition of the blood, the quality of the vessel wall, and the nature of the blood flow. Herein, we present four cases of fatal thrombus formation after a trauma, which were missed at clinical diagnosis as the symptoms were misinterpreted. We stress that a blunt trauma can be fatal because of its direct and indirect kinetic energy effects at the subacute phase. This report highlights the importance of considering thrombosis in the diagnosis of closed trauma, which is usually missed because of lack of awareness for early diagnosis and treatment or is detected too late for any therapeutic intervention, which can result in avoidable morbidity and mortality.