Detalhe da pesquisa
1.
CLDN18.2 BiTE Engages Effector and Regulatory T Cells for Antitumor Immune Response in Preclinical Models of Pancreatic Cancer.
Gastroenterology
; 165(5): 1219-1232, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37507075
2.
Rhodium Complexes Targeting DNA Mismatches as a Basis for New Therapeutics in Cancers Deficient in Mismatch Repair.
Biochemistry
; 60(26): 2055-2063, 2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34115466
3.
The serum protein transthyretin as a platform for dimerization and tetramerization of antibodies and Fab fragments to enable target clustering.
J Biol Chem
; 295(30): 10446-10455, 2020 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32518163
4.
Cell-Selective Cytotoxicity of a Fluorescent Rhodium Metalloinsertor Conjugate Results from Irreversible DNA Damage at Base Pair Mismatches.
Biochemistry
; 59(5): 717-726, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31967788
5.
Rhodium metalloinsertor binding generates a lesion with selective cytotoxicity for mismatch repair-deficient cells.
Proc Natl Acad Sci U S A
; 114(27): 6948-6953, 2017 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28634291
6.
Rapid activation of ATM on DNA flanking double-strand breaks.
Nat Cell Biol
; 9(11): 1311-8, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17952060
7.
AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer.
Cancer Discov
; 14(1): 90-103, 2024 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37861452
8.
N-substituted azaindoles as potent inhibitors of Cdc7 kinase.
Bioorg Med Chem Lett
; 23(7): 2056-60, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23481650
9.
The optimization of aminooxadiazoles as orally active inhibitors of Cdc7.
Bioorg Med Chem Lett
; 23(23): 6396-400, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24120542
10.
Emerging therapies targeting the delta-like ligand 3 (DLL3) in small cell lung cancer.
J Hematol Oncol
; 16(1): 66, 2023 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37355629
11.
Immunotherapeutic Targeting and PET Imaging of DLL3 in Small-Cell Neuroendocrine Prostate Cancer.
Cancer Res
; 83(2): 301-315, 2023 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36351060
12.
Considerations for design, manufacture, and delivery for effective and safe T-cell engager therapies.
Curr Opin Biotechnol
; 78: 102799, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36179408
13.
Hsk1-Dfp1 is required for heterochromatin-mediated cohesion at centromeres.
Nat Cell Biol
; 5(12): 1111-6, 2003 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-14625560
14.
Mesothelin/CD3 half-life extended bispecific T-cell engager molecule shows specific tumor uptake and distributes to mesothelin and CD3 expressing tissues.
J Nucl Med
; 2021 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33931466
15.
Preclinical Assessment of AMG 596, a Bispecific T-cell Engager (BiTE) Immunotherapy Targeting the Tumor-specific Antigen EGFRvIII.
Mol Cancer Ther
; 20(5): 925-933, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33632870
16.
Preclinical Assessment of a MUC12-Targeted BiTE (Bispecific T-cell Engager) Molecule.
Mol Cancer Ther
; 20(10): 1977-1987, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34376583
17.
The PSMA-targeting Half-life Extended BiTE Therapy AMG 160 has Potent Antitumor Activity in Preclinical Models of Metastatic Castration-resistant Prostate Cancer.
Clin Cancer Res
; 27(10): 2928-2937, 2021 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33504551
18.
Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring SF3B1 or U2AF1 Mutations.
Cancer Res
; 81(17): 4499-4513, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34215620
19.
AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer.
Clin Cancer Res
; 27(5): 1526-1537, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33203642
20.
DLL3: an emerging target in small cell lung cancer.
J Hematol Oncol
; 12(1): 61, 2019 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31215500