RESUMO
BACKGROUND: Since the criteria for the diagnosis of Behçet's disease was established several isolated cases have been reported to the literature with clinical manifestations associated. We tried to analyze the clinical parameters associated to this disease in 24 patients in our hospital. METHODS: A retrospective analysis was made of the patients diagnosed of Behçet's disease at Hospital General of Valencia since 1990 to 2000. The diagnosis of Behçet's disease was made by the criteria of the International Study Group for Behçet disease. Data regarding personal, clinical manifestations and clinical course were collected. RESULTS: Of the 24 cases, fourteen (58%) were men and ten (42%) were women. The median of the diagnosed was 33 years. All of them had oral recidivant ulcers. The genital ulcers appeared in twenty (83%) cases. Thirteen cases (54%) had ocular manifestations, and the skin lesions appear in 10 cases (42%). We review other clinical manifestations associated to Behçet disease: articular clinical appear in 17 cases (70%), digestive manifestations in six cases (25%), neurological manifestations three cases (12%), vascular clinical two cases (8%). CONCLUSIONS: Our results are similar to the Mediterranean expression of Behçet's disease. We must study the clinical manifestations associated to this disease that are not include in the criteria of diagnosis.
Assuntos
Síndrome de Behçet/diagnóstico , Adulto , Síndrome de Behçet/epidemiologia , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , EspanhaRESUMO
The development and activity of the nasal mucosa are influenced by many hormonal substances. In this work we realize a bibliographical review about the effect of adrenaline, thyroid hormones, corticosteroids and sex hormones on the nasal respiratory mucous membrane. We emphasize the clinic consequences.
Assuntos
Hormônios/fisiologia , Mucosa Nasal/fisiologia , Animais , Epistaxe/etiologia , Feminino , Hormônios Esteroides Gonadais/fisiologia , Hormônios/farmacologia , Humanos , Masculino , Menstruação/fisiologia , Mucosa Nasal/efeitos dos fármacos , Pólipos Nasais/fisiopatologia , Gravidez , Complicações na Gravidez/fisiopatologia , Priapismo/etiologia , Priapismo/fisiopatologia , Pseudogravidez/etiologia , Pseudogravidez/fisiopatologia , Rinite/etiologia , Espirro/fisiologiaRESUMO
Presenting a case of nasal Melanoma, in a patient previously diagnosed and treated from Rhabdomyosarcoma of the same nasal cavity. In our Department has been treated with surgery plus thymostimulin (TP-1 Serono) after surgery. Subject reviewed and clinic features, diagnostic difficulties and nowadays immunotherapy commented.
Assuntos
Melanoma/diagnóstico , Cavidade Nasal/patologia , Segunda Neoplasia Primária , Neoplasias Nasais/diagnóstico , Anticorpos Monoclonais , Tratamento Farmacológico , Humanos , Imunoterapia , Masculino , Melanoma/patologia , Melanoma/cirurgia , Pessoa de Meia-Idade , Cavidade Nasal/cirurgia , Recidiva Local de Neoplasia , Neoplasias Nasais/patologia , Neoplasias Nasais/cirurgia , Rabdomiossarcoma/patologiaRESUMO
In this paper we present a follow up of 24 patients that underwent total laryngectomy with Herrmann's technique of phonatory voice prosthesis. We discuss the complications and the facts that provoqued the removal of the prosthesis.