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1.
Nature ; 609(7926): 269-275, 2022 09.
Artigo em Inglês | MEDLINE | ID: mdl-36071190

RESUMO

Nuclear fusion is one of the most attractive alternatives to carbon-dependent energy sources1. Harnessing energy from nuclear fusion in a large reactor scale, however, still presents many scientific challenges despite the many years of research and steady advances in magnetic confinement approaches. State-of-the-art magnetic fusion devices cannot yet achieve a sustainable fusion performance, which requires a high temperature above 100 million kelvin and sufficient control of instabilities to ensure steady-state operation on the order of tens of seconds2,3. Here we report experiments at the Korea Superconducting Tokamak Advanced Research4 device producing a plasma fusion regime that satisfies most of the above requirements: thanks to abundant fast ions stabilizing the core plasma turbulence, we generate plasmas at a temperature of 100 million kelvin lasting up to 20 seconds without plasma edge instabilities or impurity accumulation. A low plasma density combined with a moderate input power for operation is key to establishing this regime by preserving a high fraction of fast ions. This regime is rarely subject to disruption and can be sustained reliably even without a sophisticated control, and thus represents a promising path towards commercial fusion reactors.

2.
Int J Biol Macromol ; 264(Pt 1): 130600, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38442829

RESUMO

We explored the rheological and tribological properties of potato starch agglomerated with a sugar binder (maltodextrin or lactose) at various concentrations by using a fluidized bed granulator. The magnitudes of consistency index and apparent viscosity of agglomerated potato starch (APS) decreased as the binder concentration was increased. Moreover, APS with a sugar binder showed lower viscoelastic moduli and higher tan δ values compared to APS with water as the binder (the control). The gel strength of all agglomerates decreased as the sugar concentration was increased. All samples showed anti-thixotropic behavior, and especially, APS with 20 % lactose showed a small anti-thixotropic area. Utilizing the Arrhenius equation clearly elucidated the effect of temperature on the apparent viscosity of all the samples. Although the maltodextrin concentration had little influence on the activation energy of APS, it increased as the lactose concentration was increased. APS samples with a sugar binder showed greater friction coefficient values compared to the control, with maltodextrin having a significant impact. The findings indicate that the rheological and tribological properties of APS rely on the type and concentration of sugar binder.


Assuntos
Solanum tuberosum , Lactose , Amido , Açúcares , Temperatura , Reologia , Viscosidade
3.
Rev Sci Instrum ; 95(7)2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-38949464

RESUMO

We developed a diamagnetic loop for the estimation of plasma stored energy in the KAIST Magnetic Mirror magnetic mirror device [Oh et al., J. Plasma Phys. 90, 975900202 (2024)]. Diamagnetic loops are used to estimate the plasma stored energy from measurements of the diamagnetic flux in plasma with an applied external magnetic field. However, diamagnetic flux measurements are accompanied by the vacuum flux, which generally exceeds the diamagnetic flux by over 10 000 times. Therefore, it is critical to attain a high signal-to-noise ratio with minimized noise in diamagnetic flux measurements. In this study, we employed a novel method to reduce background noise and improve the signal-to-noise ratio. Using two identical loops with opposite polarities, we successfully removed parasitic capacitive noise from the external insulation while amplifying the inductive signal two times. To eliminate the vacuum flux, we utilized two coaxial loops with different radii positioned at the same axial location. Results obtained from six paired loops confirmed the successful removal of the vacuum flux. The plasma stored energy was also found to agree well with Langmuir probe measurements, which verifies the diamagnetic flux measurements using the developed loop.

4.
Int J Biol Macromol ; 253(Pt 2): 126559, 2023 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-37657581

RESUMO

Our goal was to investigate the effects of various conditions of media (NaCl, sucrose, pH, and temperature) on the steady and dynamic shear rheological properties of a concentrated ternary gum mixture system (1.0 wt%) containing xanthan gum (XG), guar gum (GG), and carboxymethyl cellulose (CMC). Regardless of the media conditions, all gum mixtures exhibited a high shear-thinning behavior with a low flow behavior index (<0.30). NaCl addition resulted in a decrease in the consistency index (K, 32.8-16.1 Pa·sn) and apparent viscosity at 50 s-1 (ηa,50, 1.00-0.75 Pa·s), as well as the elastic modulus (G') and viscous modulus (G″) due to the charge screening effect. Similar result was observed with an increase in acidity of media. The presence of sucrose also induced the decrease in the ηa,50, K, G', and G″ values of the ternary gum, but tan δ (G″/G') decreased, indicative of higher weak gel-like properties. No effect of NaCl or sucrose addition on the temperature dependence of G' values was observed, whereas pH adjustment was impacted. These results demonstrated that the presence of co-solute, the acidity of media, and temperature influenced the rheological properties of ternary gum, and in particular acid condition gave a great impact.


Assuntos
Carboximetilcelulose Sódica , Cloreto de Sódio , Temperatura , Sacarose , Polissacarídeos Bacterianos/química , Gomas Vegetais/química , Concentração de Íons de Hidrogênio , Reologia , Viscosidade
5.
Rev Sci Instrum ; 94(2): 023003, 2023 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-36859064

RESUMO

Laser light scattering systems with volume Bragg grating (VBG) filters, which act as spectral/angular filters, have often been used as a point measurement technique, with spatial resolution as low as a few hundred µm, defined by the beam waist. In this work, we demonstrate how VBG filters can be leveraged for spatially resolved measurements with several µm resolution over a few millimeters along the beam propagation axis. The rejection ring, as determined by the angular acceptance criteria of the filter, is derived analytically, and the use of the ring for 1D laser line rejection is explained. For the example cases presented,i.e., for a focused probe beam waist with a diameter of ∼150 µm, the rejection ring can provide resolution up to several millimeter length along the beam propagation axis for a 1D measurement, which is also tunable. Additionally, methods to further extend the measurable region are proposed and demonstrated, using a collimation lens with a different focal length or using multiple VBG filters. The latter case can minimize the scattering signal loss, without the tradeoff of the solid angle. Such use of multiple VBGs is to extend the measurable region along the beam axis, which differs from the commonly known application of multiple filters, to improve the suppression of elastic interferences. 1D rotational Raman and Thomson scattering measurements are carried out on pulsed and DC discharges to verify this method. The system features compactness, simple implementation, high throughput, and flexibility, to accommodate various experimental conditions.

6.
Sci Rep ; 13(1): 15799, 2023 Sep 22.
Artigo em Inglês | MEDLINE | ID: mdl-37737481

RESUMO

The force-balanced state of magnetically confined plasmas heated up to 100 million degrees Celsius must be sustained long enough to achieve a burning-plasma state, such as in the case of ITER, a fusion reactor that promises a net energy gain. This force balance between the Lorentz force and the pressure gradient force, known as a plasma equilibrium, can be theoretically portrayed together with Maxwell's equations as plasmas are collections of charged particles. Nevertheless, identifying the plasma equilibrium in real time is challenging owing to its free-boundary and ill-posed conditions, which conventionally involves iterative numerical approach with a certain degree of subjective human decisions such as including or excluding certain magnetic measurements to achieve numerical convergence on the solution as well as to avoid unphysical solutions. Here, we introduce GS-DeepNet, which learns plasma equilibria through solely unsupervised learning, without using traditional numerical algorithms. GS-DeepNet includes two neural networks and teaches itself. One neural network generates a possible candidate of an equilibrium following Maxwell's equations and is taught by the other network satisfying the force balance under the equilibrium. Measurements constrain both networks. Our GS-DeepNet achieves reliable equilibria with uncertainties in contrast with existing methods, leading to possible better control of fusion-grade plasmas.

7.
Sci Rep ; 11(1): 3662, 2021 Feb 11.
Artigo em Inglês | MEDLINE | ID: mdl-33574460

RESUMO

Experimental observations assisted by 2-D imaging diagnostics on the KSTAR tokamak show that a solitary perturbation (SP) emerges prior to a boundary burst of magnetized toroidal plasmas, which puts forward SP as a potential candidate for the burst trigger. We have constructed a machine learning (ML) model based on a convolutional deep neural network architecture for a statistical study to identify the SP as a boundary burst trigger. The ML model takes sequential signals detected from 19 toroidal Mirnov coils as input and predicts whether each temporal frame corresponds to an SP. We trained the network in a supervised manner on a training set consisting of real signals with manually annotated SP locations and synthetic burst signals. The trained model achieves high performances in various metrics on a test data set. We also demonstrated the reliability of the model by visualizing the discriminative parts of the input signals that the model recognizes. Finally, we applied the trained model to new data from KSTAR experiments, which were never seen during training, and confirmed that the large burst at the plasma boundary that can fatally damage the fusion device always involves the emergence of SP. This result suggests that the SP is a key to understanding and controlling of the boundary burst in magnetized toroidal plasmas.

8.
Int J Biol Macromol ; 121: 424-428, 2019 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-30321634

RESUMO

Physical and rheological properties of agglomerated xanthan gum (XG), commonly used as a food thickener for the management of the patients with dysphagia (swallowing difficulty), were investigated at different concentrations (0, 2, 4, and 6% w/w) of hydroxypropyl methylcellulose (HPMC) as a binder in the fluidized bed agglomeration process. Flow characteristics of agglomerated XG powder were evaluated using Carr index (CI) and Hausner ratio (HR). The agglomerated XG powders obtained by HPMC binder exhibited a better flowability and higher porosity than the agglomerated powder without binder due to the size enlargement of XG powder. Dynamic moduli (G' and G") of agglomerated XG powders at 2% and 4% HPMC were significantly higher than those of other powders. The tan δ values of agglomerated powders with HPMC binder were much lower than that of an agglomerated powder without HPMC, indicating that their elastic properties were enhanced because of the addition of HPMC binder. Results suggest that the use of HPMC in agglomeration process could considerably enhance the flow characteristics and rheological properties of XG powder.


Assuntos
Derivados da Hipromelose/química , Polissacarídeos Bacterianos/química , Reologia , Porosidade
9.
Rev Sci Instrum ; 79(1): 013501, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18248028

RESUMO

An x-ray imaging crystal spectrometer was designed for the Hanbit magnetic mirror device to observe spectra of heliumlike neon at 13.4474 A. The spectrometer consists of a spherically bent mica crystal and an x-ray sensitive vacuum charge coupled device camera. This spectrometer can provide spatially resolved spectra, making it possible to obtain profiles of the ion charge state distribution from line ratios and profiles of the plasma rotation velocity from Doppler shift measurements. The paper describes measurements of spectral resolution of this instrument for low x-ray energies.

10.
Int J Biol Macromol ; 111: 77-81, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29289667

RESUMO

The intrinsic viscosity ([η]) values of binary gum mixtures with xanthan gum (XG) and guar gum (GG) mixed with NaCl and sucrose at different concentrations as well as in the presence of different pH levels were examined in dilute solution as a function of XG/GG mixing ratio (100/0, 75/25, 50/50, and 0/100). Experimental values of concentration (C) and relative viscosity (ηrel) or specific viscosity (ηsp) of gums in dilute solution were fitted to five models to determine [η] values of binary gum mixtures including individual gums. A [η] model (ηrel=1+[η]C) of Tanglertpaibul and Rao is recommended as the best model to estimate [η] values for the binary gum mixtures with XG and GG as affected by NaCl, sucrose, and pH. Overall, the synergistic interaction of XG-GG mixtures in the presence of NaCl and sucrose showed a greatly positive variation between measured and calculated values of [η]. In contrast, the binary gum mixtures showed synergy only under an acidic condition (pH3). These results suggest that the NaCl and sucrose addition or acidic condition appears to affect the intermolecular interaction occurred between XG and GG at different gum mixing ratios.


Assuntos
Galactanos/química , Mananas/química , Gomas Vegetais/química , Polissacarídeos Bacterianos/química , Reologia , Viscosidade , Concentração de Íons de Hidrogênio , Cloreto de Sódio/farmacologia , Sacarose/farmacologia
11.
Int J Biol Macromol ; 115: 124-128, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-29654858

RESUMO

The effect of CMC on the steady and dynamic shear rheological properties of binary mixtures of XG and GG was examined at different mixing ratios. All XG-GG-CMC ternary mixtures had high shear-thinning behavior and the n value of the sample with 5% CMC was the smallest compared with those of other samples. A marked increase in K and ηa,50 values was observed for ternary mixtures at a lower content (5%) of CMC, indicating that the synergistic interactions of the XG-GG binary mixture were affected by the content of CMC. The effect of temperature on the ηa,50 was well described by the Arrhenius equation for all samples. The activation energy values of all ternary gum mixtures are higher than that of binary gum mixture, and these values also decreased with an increase in CMC content from 5 to 15%. The dynamic moduli of ternary gum mixtures decreased with an increase in CMC content. The tan δ value of the ternary gum mixture with 5% CMC was much lower than those of other ternary mixtures. In general, these results suggest that the flow and dynamic shear rheological properties of XG-GG binary mixtures are strongly influenced by a small addition of CMC.


Assuntos
Celulase/química , Galactanos/química , Mananas/química , Gomas Vegetais/química , Polissacarídeos Bacterianos/química , Reologia , Resistência ao Cisalhamento , Temperatura
12.
Int J Oral Maxillofac Surg ; 47(12): 1596-1603, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30017572

RESUMO

Coronectomy is a widely accepted treatment for mandibular third molars that are in close relationship to the mandibular canal. However, long-term studies on morbidity following this procedure have not been presented. The aim of this study was to examine the long-term morbidity after coronectomy, with sensory disturbances of the inferior alveolar nerve (IAN) and root migration as the primary outcome variables. A total of 231 mandibular third molar coronectomies were performed in 191 patients with a mean follow-up period of 5.7years (range 1-12years). The prevalence of IAN injury was 1.3%, and 3.5% of the retained roots were removed. None of the reoperations to remove the retained roots caused IAN impairment. Infections occurred in 11.7% of the cases and all were treated with antibiotics. Overall, 97% of the retained roots showed signs of migration and 65% showed signs of rotation. Therefore, coronectomy of the mandibular third molars with an intimate relationship to the mandibular canal seems to be a safe treatment modality with a good long-term prognosis.


Assuntos
Dente Serotino/cirurgia , Coroa do Dente/cirurgia , Dente Impactado/cirurgia , Adolescente , Adulto , Idoso , Feminino , Seguimentos , Humanos , Traumatismos do Nervo Lingual/etiologia , Masculino , Mandíbula , Pessoa de Meia-Idade , Estudos Prospectivos , Reoperação , Retalhos Cirúrgicos , Infecção da Ferida Cirúrgica/tratamento farmacológico , Raiz Dentária/patologia , Resultado do Tratamento , Traumatismos do Nervo Trigêmeo/etiologia
13.
Rev Sci Instrum ; 89(10): 10K106, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30399691

RESUMO

A Bayesian with Gaussian process-based numerical method to impute a few missing magnetic signals caused by impaired magnetic probes during tokamak operations is developed such that the real-time reconstruction of magnetic equilibria, whose performance strongly depends on the measured magnetic signals and their intactness, is affected minimally. Likelihood of the Bayesian model constructed with Maxwell's equations, specifically Gauss's law for magnetism and Ampère's law, results in an infinite number of solutions if two or more magnetic signals are missing. This undesirable characteristic of the Bayesian model is remediated by coupling the model with the Gaussian process. Our proposed numerical method infers nine non-consecutive missing magnetic signals correctly in less than 1 ms suitable for the real-time reconstruction of magnetic equilibria during tokamak operations.

14.
Curr Biol ; 9(14): 751-4, 1999 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-10421579

RESUMO

Mobilization of Ca2+ from intracellular stores is an important mechanism for generating cytoplasmic Ca2+ signals [1]. Two families of intracellular Ca(2+)-release channels - the inositol-1,4, 5-trisphosphate (IP3) receptors and the ryanodine receptors (RyRs) - have been described in mammalian tissues [2]. Recently, nicotinic acid adenine dinucleotide phosphate (NAADP), a molecule derived from NADP+, has been shown to trigger Ca2+ release from intracellular stores in invertebrate eggs [3] [4] [5] [6] and pancreatic acinar cells [7]. The nature of NAADP-induced Ca2+ release is unknown but it is clearly distinct from the IP3- and cyclic ADP ribose (cADPR)-sensitive mechanisms in eggs (reviewed in [8] [9]). Furthermore, mammalian cells can synthesize and degrade NAADP, suggesting that NAADP-induced Ca2+ release may be widespread and thus contribute to the complexity of Ca2+ signalling [10] [11]. Here, we show for the first time that NAADP evokes Ca2+ release from rat brain microsomes by a mechanism that is distinct from those sensitive to IP3 or cADPR, and has a remarkably similar pharmacology to the action of NAADP in sea urchin eggs [12]. Membranes prepared from the same rat brain tissues are able to support the synthesis and degradation of NAADP. We therefore suggest that NAADP-mediated Ca2+ signalling could play an important role in neuronal Ca2+ signalling.


Assuntos
Encéfalo/efeitos dos fármacos , Cálcio/metabolismo , Microssomos/efeitos dos fármacos , NAD/análogos & derivados , Animais , Relação Dose-Resposta a Droga , Concentração de Íons de Hidrogênio , Técnicas In Vitro , NAD/metabolismo , NAD/farmacologia , Ratos , Ratos Sprague-Dawley , Ouriços-do-Mar , Transdução de Sinais , Fatores de Tempo
15.
Curr Biol ; 11(12): 987-90, 2001 Jun 26.
Artigo em Inglês | MEDLINE | ID: mdl-11448777

RESUMO

Alongside the well-studied inositol 1,4,5 trisphosphate and ryanodine receptors, evidence is gathering that a new intracellular release mechanism, gated by the pyridine nucleotide nicotinic acid adenine dinucleotide phosphate (NAADP), is present in numerous organisms, ranging from plant to mammalian cells (reviewed in [1]). Most cells have been shown to express at least two Ca(2+)-release mechanisms controlled by different messengers, and this can lead to redundancy, convergence, or divergence of responses. One exception appears to be muscle and heart contractile tissues. Here, it is thought that the dominant intracellular channel is the ryanodine receptor, while IP(3) receptors are poorly expressed and their role appears to be negligible. We now report that NAADP receptors are functional and abundant in cardiac microsomes. NAADP binds specifically and with high affinity (130 pM and 4 nM) to two sites on cardiac microsomes and releases Ca(2+) with an apparent EC(50) of 323 +/- 14 nM. Furthermore, binding experiments show that this receptor displays both positive and negative cooperativity, a peculiarity unique among intracellular Ca(2+) channels. Therefore, we show that the heart possesses multiple mechanisms to increase the complexity of Ca(2+) signaling and that NAADP may be integral in the functioning of this organ.


Assuntos
Adenosina Difosfato Ribose/análogos & derivados , Cálcio/metabolismo , ADP-Ribose Cíclica/análogos & derivados , Microssomos/metabolismo , Miocárdio/metabolismo , NADP/análogos & derivados , NADP/metabolismo , Receptores de Superfície Celular/metabolismo , Adenosina Difosfato Ribose/farmacologia , Animais , Bloqueadores dos Canais de Cálcio/farmacologia , Diltiazem/farmacologia , Indicadores e Reagentes/farmacologia , Cinética , Microssomos/química , Microssomos/efeitos dos fármacos , Ligação Proteica , Ensaio Radioligante , Rutênio Vermelho/farmacologia , Rianodina/farmacologia , Verapamil/farmacologia
16.
Rev Sci Instrum ; 78(4): 043504, 2007 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17477657

RESUMO

An analog integrator, which automatically compensates an integrating drift, has been developed for the magnetic diagnostics in the Korea superconducting tokamak advanced research (KSTAR). The compensation of the drift is done by the analog to digital converter-register-digital to analog converter in the integrator. The integrator will be used in the equilibrium magnetic field measurements by using inductive magnetic sensors during a plasma discharge in the KSTAR machine. Two differential amplifiers are added to the signal path between each magnetic sensor and the integrator in order to improve the performance of the integrator because a long signal cable of 100 m will be used for the measurement in the KSTAR machine. In this work, the characteristics of the integrator with two differential amplifiers are experimentally investigated.

17.
Rev Sci Instrum ; 78(6): 063504, 2007 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17614609

RESUMO

An advanced x-ray imaging crystal spectrometer (XICS) for KSTAR tokamak has been developed by utilizing a segmented two dimensional (2D) position-sensitive multiwire proportional counter. The XICS for the KSTAR tokamak provides time-resolved measurements of the radial ion and electron temperature profiles, toroidal plasma rotation velocity, and ionization equilibrium. The segmented 2D detector with delay-line readout and supporting electronics has been adopted to improve the photon count rate capability. The current fabrication status of the XICS for the KSTAR tokamak and the first performance test results of the prototype segmented 2D detector are presented.


Assuntos
Radiometria/instrumentação , Espectrometria por Raios X/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Doses de Radiação , Radiometria/métodos , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Espectrometria por Raios X/métodos
18.
Rev Sci Instrum ; 78(10): 103504, 2007 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17979416

RESUMO

A versatile time-to-digital converter based data acquisition system for a segmented position-sensitive detector has been developed. This data acquisition system was successfully demonstrated to a two-segment position-sensitive detector. The data acquisition system will be developed further to support multisegmented position-sensitive detector to improve the photon count rate capability of the advanced x-ray imaging crystal spectrometer system.


Assuntos
Cristalografia/instrumentação , Armazenamento e Recuperação da Informação/métodos , Processamento de Sinais Assistido por Computador/instrumentação , Espectrometria por Raios X/instrumentação , Transdutores , Cristalografia/métodos , Desenho de Equipamento , Análise de Falha de Equipamento , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Espectrometria por Raios X/métodos
19.
Nanoscale Res Lett ; 12(1): 433, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28673051

RESUMO

Magnetic biochar nanocomposites were obtained by modification of biochar by zero-valent iron. The article provides information on the impact of contact time, initial Cd(II), Co(II), Zn(II), and Pb(II) ion concentrations, dose of the sorbents, solution pH and temperature on the adsorption capacity. On the basis of experiments, it was found that the optimum parameters for the sorption process are phase contact time 360 min (after this time, the equilibrium of all concentrations is reached), the dose of sorbent equal to 5 g/dm3, pH 5 and the temperature 295 K. The values of parameters calculated from the kinetic models and isotherms present the best match to the pseudo second order and Langmuir isotherm models. The calculated thermodynamic parameters ∆H 0, ∆S 0 and ∆G 0 indicate that the sorption of heavy metal ions is an exothermic and spontaneous process as well as favoured at lower temperatures, suggesting the physical character of sorption. The solution of nitric acid(V) at the concentration 0.1 mol/dm3 was the best acidic desorbing agent used for regeneration of metal-loaded magnetic sorbents. The physicochemical properties of synthesized composites were characterized by FTIR, SEM, XRD, XPS and TG analyses. The point characteristics of the double layer for biochar pHPZC and pHIEP were designated.

20.
Sci Rep ; 7: 45075, 2017 03 24.
Artigo em Inglês | MEDLINE | ID: mdl-28338046

RESUMO

Solitary perturbations (SPs) localized both poloidally and radially are detected within ~100 µs before the partial collapse of the high pressure gradient boundary region (called pedestal) of magnetized toroidal plasma in the KSTAR tokamak device. The SP develops with a low toroidal mode number (typically unity) in the pedestal ingrained with quasi-stable edge-localized mode (QSM) which commonly appears during the inter-collapse period. The SPs have smaller mode pitch and different (often opposite) rotation velocity compared to the QSMs. Similar solitary perturbations are also frequently observed before the onset of complete pedestal collapse, suggesting a strong connection between the SP generation and the pedestal collapse.

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