Detalhe da pesquisa
1.
Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies.
Arch Toxicol
; 95(6): 1867-1897, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851225
2.
Assessment of developmental neurotoxicity induced by chemical mixtures using an adverse outcome pathway concept.
Environ Health
; 19(1): 23, 2020 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32093744
3.
Development and analysis of an adverse outcome pathway network for human neurotoxicity.
Arch Toxicol
; 93(10): 2759-2772, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31444508
4.
Development of the Adverse Outcome Pathway (AOP): Chronic binding of antagonist to N-methyl-d-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities of children.
Toxicol Appl Pharmacol
; 354: 153-175, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29524501
5.
Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods.
Toxicol Appl Pharmacol
; 354: 7-18, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29476865
6.
Early life exposure to air pollution particulate matter (PM) as risk factor for attention deficit/hyperactivity disorder (ADHD): Need for novel strategies for mechanisms and causalities.
Toxicol Appl Pharmacol
; 354: 196-214, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29550511
7.
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes.
Toxicol Appl Pharmacol
; 354: 3-6, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29447839
8.
An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition.
Arch Toxicol
; 92(1): 41-82, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29209747
9.
Putative adverse outcome pathways relevant to neurotoxicity.
Crit Rev Toxicol
; 45(1): 83-91, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605028
10.
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.
Arch Toxicol
; 89(2): 269-87, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25618548
11.
Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox.
Int J Mol Sci
; 15(1): 905-26, 2014 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24413757
12.
Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps.
Front Toxicol
; 6: 1285768, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38523647
13.
Editorial: Developmental neurotoxicity.
Toxicol Appl Pharmacol
; 354: 1-2, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30030094
14.
miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing.
Cell Biol Toxicol
; 29(4): 239-57, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23903816
15.
Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death.
J Immunol
; 186(8): 4973-83, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21402900
16.
Prediction of in vivo prenatal chlorpyrifos exposure leading to developmental neurotoxicity in humans based on in vitro toxicity data by quantitative in vitro-in vivo extrapolation.
Front Pharmacol
; 14: 1136174, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36959852
17.
Assessment of neurotransmitter release in human iPSC-derived neuronal/glial cells: a missing in vitro assay for regulatory developmental neurotoxicity testing.
Reprod Toxicol
; 117: 108358, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36863571
18.
Upscaling biological complexity to boost neuronal and oligodendroglia maturation and improve in vitro developmental neurotoxicity (DNT) evaluation.
Reprod Toxicol
; 110: 124-140, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35378221
19.
Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells.
Reprod Toxicol
; 112: 36-50, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35697279
20.
Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network.
Comput Toxicol
; 21: 100206, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35211661