Pesquisa | BVS Violência e Saúde

1.

A Randomized Controlled Trial of OPT-302, a VEGF-C/D Inhibitor for Neovascular Age-Related Macular Degeneration.

Jackson, Timothy L; Slakter, Jason; Buyse, Marc; Wang, Kun; Dugel, Pravin U; Wykoff, Charles C; Boyer, David S; Gerometta, Michael; Baldwin, Megan E; Price, Clare F.

Ophthalmology ; 130(6): 588-597, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36754174

2.

Differential expression of VEGF ligands and receptors in prostate cancer.

Woollard, David J; Opeskin, Kenneth; Coso, Sanja; Wu, Di; Baldwin, Megan E; Williams, Elizabeth D.

Prostate ; 73(6): 563-72, 2013 May.

Artigo em Inglês | MEDLINE | ID: mdl-23038639

3.

Lymphangiogenesis and cancer metastasis.

Stacker, Steven A; Achen, Marc G; Jussila, Lotta; Baldwin, Megan E; Alitalo, Kari.

Nat Rev Cancer ; 2(8): 573-83, 2002 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-12154350

4.

Corneal avascularity is due to soluble VEGF receptor-1.

Ambati, Balamurali K; Nozaki, Miho; Singh, Nirbhai; Takeda, Atsunobu; Jani, Pooja D; Suthar, Tushar; Albuquerque, Romulo J C; Richter, Elizabeth; Sakurai, Eiji; Newcomb, Michael T; Kleinman, Mark E; Caldwell, Ruth B; Lin, Qing; Ogura, Yuichiro; Orecchia, Angela; Samuelson, Don A; Agnew, Dalen W; St Leger, Judy; Green, W Richard; Mahasreshti, Parameshwar J; Curiel, David T; Kwan, Donna; Marsh, Helene; Ikeda, Sakae; Leiper, Lucy J; Collinson, J Martin; Bogdanovich, Sasha; Khurana, Tejvir S; Shibuya, Masabumi; Baldwin, Megan E; Ferrara, Napoleone; Gerber, Hans-Peter; De Falco, Sandro; Witta, Jassir; Baffi, Judit Z; Raisler, Brian J; Ambati, Jayakrishna.

Nature ; 443(7114): 993-7, 2006 Oct 26.

Artigo em Inglês | MEDLINE | ID: mdl-17051153

5.

Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D.

McColl, Bradley K; Baldwin, Megan E; Roufail, Sally; Freeman, Craig; Moritz, Robert L; Simpson, Richard J; Alitalo, Kari; Stacker, Steven A; Achen, Marc G.

J Exp Med ; 198(6): 863-8, 2003 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-12963694

6.

Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells.

Shojaei, Farbod; Wu, Xiumin; Malik, Ajay K; Zhong, Cuiling; Baldwin, Megan E; Schanz, Stefanie; Fuh, Germaine; Gerber, Hans-Peter; Ferrara, Napoleone.

Nat Biotechnol ; 25(8): 911-20, 2007 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-17664940

7.

Phase 1 Study of OPT-302 Inhibition of Vascular Endothelial Growth Factors C and D for Neovascular Age-Related Macular Degeneration.

Dugel, Pravin U; Boyer, David S; Antoszyk, Andrew N; Steinle, Nathan C; Varenhorst, Michael P; Pearlman, Joel A; Gillies, Mark C; Finger, Robert P; Baldwin, Megan E; Leitch, Ian M.

Ophthalmol Retina ; 4(3): 250-263, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31924544

8.

Vascular endothelial growth factor D is dispensable for development of the lymphatic system.

Baldwin, Megan E; Halford, Michael M; Roufail, Sally; Williams, Richard A; Hibbs, Margaret L; Grail, Dianne; Kubo, Hajime; Stacker, Steven A; Achen, Marc G.

Mol Cell Biol ; 25(6): 2441-9, 2005 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-15743836

9.

Molecular pathways for lymphangiogenesis and their role in human disease.

Stacker, Steven A; Farnsworth, Rae H; Karnezis, Tara; Shayan, Ramin; Smith, Darrin P; Paavonen, Karri; Davydova, Natalia; Caesar, Carol; Inder, Rachael; Baldwin, Megan E; McColl, Bradley K; Roufail, Sally; Williams, Richard A; Hughes, Richard A; Alitalo, Kari; Achen, Marc G.

Novartis Found Symp ; 281: 38-43; discussion 44-53, 208-9, 2007.

Artigo em Inglês | MEDLINE | ID: mdl-17534064

10.

The role of tumor lymphangiogenesis in metastatic spread.

Stacker, Steven A; Baldwin, Megan E; Achen, Marc G.

FASEB J ; 16(9): 922-34, 2002 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-12087053

11.

Regenerating lizard tails: a new model for investigating lymphangiogenesis.

Daniels, Christopher B; Lewis, Benjamin C; Tsopelas, Chris; Munns, Suzanne L; Orgeig, Sandra; Baldwin, Megan E; Stacker, Steven A; Achen, Marc G; Chatterton, Barry E; Cooter, Rodney D.

FASEB J ; 17(3): 479-81, 2003 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-12514111

12.

Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer.

Zeng, Yiping; Opeskin, Kenneth; Baldwin, Megan E; Horvath, Lisa G; Achen, Marc G; Stacker, Steven A; Sutherland, Robert L; Williams, Elizabeth D.

Clin Cancer Res ; 10(15): 5137-44, 2004 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-15297417

13.

VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium.

Karnezis, Tara; Shayan, Ramin; Caesar, Carol; Roufail, Sally; Harris, Nicole C; Ardipradja, Kathryn; Zhang, You Fang; Williams, Steven P; Farnsworth, Rae H; Chai, Ming G; Rupasinghe, Thusitha W T; Tull, Dedreia L; Baldwin, Megan E; Sloan, Erica K; Fox, Stephen B; Achen, Marc G; Stacker, Steven A.

Cancer Cell ; 21(2): 181-95, 2012 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-22340592

14.

Deletion of vascular endothelial growth factor C (VEGF-C) and VEGF-D is not equivalent to VEGF receptor 3 deletion in mouse embryos.

Haiko, Paula; Makinen, Taija; Keskitalo, Salla; Taipale, Jussi; Karkkainen, Marika J; Baldwin, Megan E; Stacker, Steven A; Achen, Marc G; Alitalo, Kari.

Mol Cell Biol ; 28(15): 4843-50, 2008 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-18519586

15.

Redundant roles of VEGF-B and PlGF during selective VEGF-A blockade in mice.

Malik, Ajay K; Baldwin, Megan E; Peale, Franklin; Fuh, Germaine; Liang, Wei-Ching; Lowman, Henry; Meng, Gloria; Ferrara, Napoleone; Gerber, Hans-Peter.

Blood ; 107(2): 550-7, 2006 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-16189273

16.

Molecular control of lymphangiogenesis.

Baldwin, Megan E; Stacker, Steven A; Achen, Marc G.

Bioessays ; 24(11): 1030-40, 2002 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-12386934

17.

The angiogenic and lymphangiogenic factor vascular endothelial growth factor-D exhibits a paracrine mode of action in cancer.

Achen, Marc G; Williams, Richard A; Baldwin, Megan E; Lai, Patricia; Roufail, Sally; Alitalo, Kari; Stacker, Steven A.

Growth Factors ; 20(2): 99-107, 2002 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-12148568

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