RESUMO
Having excluded common structural, inflammatory and vascular causes of a spastic paraparesis, the diagnostic yield of further clinical investigations is low. Here, we show that testing for rare metabolic and genetic causes can have important implications for both the patient and their family.
Assuntos
Transportadores de Cassetes de Ligação de ATP/genética , Paraparesia Espástica/genética , Membro 1 da Subfamília D de Transportadores de Cassetes de Ligação de ATP , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Mutação , LinhagemRESUMO
We present a case of spontaneous regression of a neuroendocrine tumor following pregnancy in the absence of chemotherapy, radiotherapy, or alternative medicine (including herbal medicine). The diagnosis of a nonsecretory carcinoid tumor was confirmed using CT imaging, octreotide scan, and histology. Furthermore, serial imaging has demonstrated spontaneous regression of the carcinoid suggesting that pregnancy did not worsen the course of the disease but instead may have contributed to tumour regression. We discuss mechanisms underlying tumour regression and the possible effect of pregnancy on these processes.