Detalhe da pesquisa
1.
TSC2 S1365A mutation potently regulates CD8+ T cell function and differentiation and improves adoptive cellular cancer therapy.
JCI Insight
; 8(21)2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37788104
2.
Synthesis of Highly Potent N-10 Amino-Linked DNA-Alkylating Indolinobenzodiazepine Antibody-Drug Conjugates (ADCs).
ACS Med Chem Lett
; 10(8): 1211-1215, 2019 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31413807
3.
Peptide-Cleavable Self-immolative Maytansinoid Antibody-Drug Conjugates Designed To Provide Improved Bystander Killing.
ACS Med Chem Lett
; 10(10): 1393-1399, 2019 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31620224
4.
Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha-Targeting Antibody-Drug Conjugate, Potentiates the Activity of Standard of Care Therapeutics in Ovarian Cancer Models.
Neoplasia
; 18(12): 775-784, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27889646
5.
IMGN853, a Folate Receptor-α (FRα)-Targeting Antibody-Drug Conjugate, Exhibits Potent Targeted Antitumor Activity against FRα-Expressing Tumors.
Mol Cancer Ther
; 14(7): 1605-13, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25904506
6.
Tumor-specific novel taxoid-monoclonal antibody conjugates.
J Med Chem
; 45(26): 5620-3, 2002 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-12477344
7.
SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies.
Clin Cancer Res
; 20(17): 4574-83, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24987056
8.
Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria.
Proc Natl Acad Sci U S A
; 101(21): 7988-93, 2004 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-15148411
9.
An anti-apoptotic viral protein that recruits Bax to mitochondria.
J Biol Chem
; 279(21): 22605-14, 2004 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15004026