Pesquisa | BVS Violência e Saúde

1.

Implementing Genome-Driven Oncology.

Hyman, David M; Taylor, Barry S; Baselga, José.

Cell ; 168(4): 584-599, 2017 02 09.

Artigo em Inglês | MEDLINE | ID: mdl-28187282

2.

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

Bruna, Alejandra; Rueda, Oscar M; Greenwood, Wendy; Batra, Ankita Sati; Callari, Maurizio; Batra, Rajbir Nath; Pogrebniak, Katherine; Sandoval, Jose; Cassidy, John W; Tufegdzic-Vidakovic, Ana; Sammut, Stephen-John; Jones, Linda; Provenzano, Elena; Baird, Richard; Eirew, Peter; Hadfield, James; Eldridge, Matthew; McLaren-Douglas, Anne; Barthorpe, Andrew; Lightfoot, Howard; O'Connor, Mark J; Gray, Joe; Cortes, Javier; Baselga, Jose; Marangoni, Elisabetta; Welm, Alana L; Aparicio, Samuel; Serra, Violeta; Garnett, Mathew J; Caldas, Carlos.

Cell ; 167(1): 260-274.e22, 2016 09 22.

Artigo em Inglês | MEDLINE | ID: mdl-27641504

3.

The evolving war on cancer.

Haber, Daniel A; Gray, Nathanael S; Baselga, Jose.

Cell ; 145(1): 19-24, 2011 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-21458664

4.

Author Correction: Tumour lineage shapes BRCA-mediated phenotypes.

Jonsson, Philip; Bandlamudi, Chaitanya; Cheng, Michael L; Srinivasan, Preethi; Chavan, Shweta S; Friedman, Noah D; Rosen, Ezra Y; Richards, Allison L; Bouvier, Nancy; Selcuklu, S Duygu; Bielski, Craig M; Abida, Wassim; Mandelker, Diana; Birsoy, Ozge; Zhang, Liying; Zehir, Ahmet; Donoghue, Mark T A; Baselga, José; Offit, Kenneth; Scher, Howard I; O'Reilly, Eileen M; Stadler, Zsofia K; Schultz, Nikolaus; Socci, Nicholas D; Viale, Agnes; Ladanyi, Marc; Robson, Mark E; Hyman, David M; Berger, Michael F; Solit, David B; Taylor, Barry S.

Nature ; 577(7789): E1, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31822847

5.

A view on drug resistance in cancer.

Vasan, Neil; Baselga, José; Hyman, David M.

Nature ; 575(7782): 299-309, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31723286

6.

Tumour lineage shapes BRCA-mediated phenotypes.

Jonsson, Philip; Bandlamudi, Chaitanya; Cheng, Michael L; Srinivasan, Preethi; Chavan, Shweta S; Friedman, Noah D; Rosen, Ezra Y; Richards, Allison L; Bouvier, Nancy; Selcuklu, S Duygu; Bielski, Craig M; Abida, Wassim; Mandelker, Diana; Birsoy, Ozge; Zhang, Liying; Zehir, Ahmet; Donoghue, Mark T A; Baselga, José; Offit, Kenneth; Scher, Howard I; O'Reilly, Eileen M; Stadler, Zsofia K; Schultz, Nikolaus; Socci, Nicholas D; Viale, Agnes; Ladanyi, Marc; Robson, Mark E; Hyman, David M; Berger, Michael F; Solit, David B; Taylor, Barry S.

Nature ; 571(7766): 576-579, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31292550

7.

Author Correction: HER kinase inhibition in patients with HER2- and HER3-mutant cancers.

Hyman, David M; Piha-Paul, Sarina A; Won, Helen; Rodon, Jordi; Saura, Cristina; Shapiro, Geoffrey I; Juric, Dejan; Quinn, David I; Moreno, Victor; Doger, Bernard; Mayer, Ingrid A; Boni, Valentina; Calvo, Emiliano; Loi, Sherene; Lockhart, Albert C; Erinjeri, Joseph P; Scaltriti, Maurizio; Ulaner, Gary A; Patel, Juber; Tang, Jiabin; Beer, Hannah; Selcuklu, S Duygu; Hanrahan, Aphrothiti J; Bouvier, Nancy; Melcer, Myra; Murali, Rajmohan; Schram, Alison M; Smyth, Lillian M; Jhaveri, Komal; Li, Bob T; Drilon, Alexander; Harding, James J; Iyer, Gopa; Taylor, Barry S; Berger, Michael F; Cutler, Richard E; Xu, Feng; Butturini, Anna; Eli, Lisa D; Mann, Grace; Farrell, Cynthia; Lalani, Alshad S; Bryce, Richard P; Arteaga, Carlos L; Meric-Bernstam, Funda; Baselga, José; Solit, David B.

Nature ; 566(7745): E11-E12, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30755741

8.

HER kinase inhibition in patients with HER2- and HER3-mutant cancers.

Hyman, David M; Piha-Paul, Sarina A; Won, Helen; Rodon, Jordi; Saura, Cristina; Shapiro, Geoffrey I; Juric, Dejan; Quinn, David I; Moreno, Victor; Doger, Bernard; Mayer, Ingrid A; Boni, Valentina; Calvo, Emiliano; Loi, Sherene; Lockhart, Albert C; Erinjeri, Joseph P; Scaltriti, Maurizio; Ulaner, Gary A; Patel, Juber; Tang, Jiabin; Beer, Hannah; Selcuklu, S Duygu; Hanrahan, Aphrothiti J; Bouvier, Nancy; Melcer, Myra; Murali, Rajmohan; Schram, Alison M; Smyth, Lillian M; Jhaveri, Komal; Li, Bob T; Drilon, Alexander; Harding, James J; Iyer, Gopa; Taylor, Barry S; Berger, Michael F; Cutler, Richard E; Xu, Feng; Butturini, Anna; Eli, Lisa D; Mann, Grace; Farrell, Cynthia; Lalani, Alshad S; Bryce, Richard P; Arteaga, Carlos L; Meric-Bernstam, Funda; Baselga, José; Solit, David B.

Nature ; 554(7691): 189-194, 2018 02 08.

Artigo em Inglês | MEDLINE | ID: mdl-29420467

9.

Recurrent and functional regulatory mutations in breast cancer.

Rheinbay, Esther; Parasuraman, Prasanna; Grimsby, Jonna; Tiao, Grace; Engreitz, Jesse M; Kim, Jaegil; Lawrence, Michael S; Taylor-Weiner, Amaro; Rodriguez-Cuevas, Sergio; Rosenberg, Mara; Hess, Julian; Stewart, Chip; Maruvka, Yosef E; Stojanov, Petar; Cortes, Maria L; Seepo, Sara; Cibulskis, Carrie; Tracy, Adam; Pugh, Trevor J; Lee, Jesse; Zheng, Zongli; Ellisen, Leif W; Iafrate, A John; Boehm, Jesse S; Gabriel, Stacey B; Meyerson, Matthew; Golub, Todd R; Baselga, Jose; Hidalgo-Miranda, Alfredo; Shioda, Toshi; Bernards, Andre; Lander, Eric S; Getz, Gad.

Nature ; 547(7661): 55-60, 2017 07 06.

Artigo em Inglês | MEDLINE | ID: mdl-28658208

10.

Patient-reported function, health-related quality of life, and symptoms in APHINITY: pertuzumab plus trastuzumab and chemotherapy in HER2-positive early breast cancer.

Bines, José; Clark, Emma; Barton, Claire; Restuccia, Eleonora; Procter, Marion; Sonnenblick, Amir; Fumagalli, Debora; Parlier, Damien; Arahmani, Amal; Baselga, José; Viale, Giuseppe; Reaby, Linda L; Frank, Elizabeth; Gelber, Richard D; Piccart, Martine; Jackisch, Christian; Petersen, Jennifer A.

Br J Cancer ; 125(1): 38-47, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33828257

11.

Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.

Juric, Dejan; Castel, Pau; Griffith, Malachi; Griffith, Obi L; Won, Helen H; Ellis, Haley; Ebbesen, Saya H; Ainscough, Benjamin J; Ramu, Avinash; Iyer, Gopa; Shah, Ronak H; Huynh, Tiffany; Mino-Kenudson, Mari; Sgroi, Dennis; Isakoff, Steven; Thabet, Ashraf; Elamine, Leila; Solit, David B; Lowe, Scott W; Quadt, Cornelia; Peters, Malte; Derti, Adnan; Schegel, Robert; Huang, Alan; Mardis, Elaine R; Berger, Michael F; Baselga, José; Scaltriti, Maurizio.

Nature ; 518(7538): 240-4, 2015 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-25409150

12.

The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth.

Bago, Ruzica; Sommer, Eeva; Castel, Pau; Crafter, Claire; Bailey, Fiona P; Shpiro, Natalia; Baselga, José; Cross, Darren; Eyers, Patrick A; Alessi, Dario R.

EMBO J ; 35(17): 1902-22, 2016 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-27481935

13.

A Phase II Trial of Cabozantinib in Hormone Receptor-Positive Breast Cancer with Bone Metastases.

Xu, Jing; Higgins, Michaela J; Tolaney, Sara M; Come, Steven E; Smith, Matthew R; Fornier, Monica; Mahmood, Umar; Baselga, Jose; Yeap, Beow Y; Chabner, Bruce A; Isakoff, Steven J.

Oncologist ; 25(8): 652-660, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32463152

14.

Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer.

von Minckwitz, Gunter; Procter, Marion; de Azambuja, Evandro; Zardavas, Dimitrios; Benyunes, Mark; Viale, Giuseppe; Suter, Thomas; Arahmani, Amal; Rouchet, Nathalie; Clark, Emma; Knott, Adam; Lang, Istvan; Levy, Christelle; Yardley, Denise A; Bines, Jose; Gelber, Richard D; Piccart, Martine; Baselga, Jose.

N Engl J Med ; 377(2): 122-131, 2017 Jul 13.

Artigo em Inglês | MEDLINE | ID: mdl-28581356

15.

Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy.

Di Cosimo, Serena; Appierto, Valentina; Pizzamiglio, Sara; Silvestri, Marco; Baselga, José; Piccart, Martine; Huober, Jens; Izquierdo, Miguel; de la Pena, Lorena; Hilbers, Florentine S; de Azambuja, Evandro; Untch, Michael; Pusztai, Lajos; Pritchard, Kathleen; Nuciforo, Paolo; Vincent-Salomon, Anne; Symmans, Fraser; Apolone, Giovanni; de Braud, Filippo G; Iorio, Marilena V; Verderio, Paolo; Daidone, Maria Grazia.

Int J Mol Sci ; 21(4)2020 Feb 18.

Artigo em Inglês | MEDLINE | ID: mdl-32085669

16.

Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.

Saura, Cristina; Hlauschek, Dominik; Oliveira, Mafalda; Zardavas, Dimitrios; Jallitsch-Halper, Anita; de la Peña, Lorena; Nuciforo, Paolo; Ballestrero, Alberto; Dubsky, Peter; Lombard, Janine M; Vuylsteke, Peter; Castaneda, Carlos A; Colleoni, Marco; Santos Borges, Giuliano; Ciruelos, Eva; Fornier, Monica; Boer, Katalin; Bardia, Aditya; Wilson, Timothy R; Stout, Thomas J; Hsu, Jerry Y; Shi, Yi; Piccart, Martine; Gnant, Michael; Baselga, José; de Azambuja, Evandro.

Lancet Oncol ; 20(9): 1226-1238, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31402321

17.

MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer.

Novoplansky, Ofra; Fury, Matthew; Prasad, Manu; Yegodayev, Ksenia; Zorea, Jonathan; Cohen, Limor; Pelossof, Raphael; Cohen, Liz; Katabi, Nora; Cecchi, Fabiola; Joshua, Ben-Zion; Popovtzer, Aron; Baselga, Jose; Scaltriti, Maurizio; Elkabets, Moshe.

Int J Cancer ; 145(3): 748-762, 2019 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-30694565

18.

Pregnancies during and after trastuzumab and/or lapatinib in patients with human epidermal growth factor receptor 2-positive early breast cancer: Analysis from the NeoALTTO (BIG 1-06) and ALTTO (BIG 2-06) trials.

Lambertini, Matteo; Martel, Samuel; Campbell, Christine; Guillaume, Sébastien; Hilbers, Florentine S; Schuehly, Uwe; Korde, Larissa; Azim, Hatem A; Di Cosimo, Serena; Tenglin, Richard C; Huober, Jens; Baselga, José; Moreno-Aspitia, Alvaro; Piccart-Gebhart, Martine; Gelber, Richard D; de Azambuja, Evandro; Ignatiadis, Michail.

Cancer ; 125(2): 307-316, 2019 01 15.

Artigo em Inglês | MEDLINE | ID: mdl-30335191

19.

Everolimus plus Exemestane for Hormone Receptor-Positive Advanced Breast Cancer: A PAM50 Intrinsic Subtype Analysis of BOLERO-2.

Prat, Aleix; Brase, Jan Christoph; Cheng, Yuan; Nuciforo, Paolo; Paré, Laia; Pascual, Tomás; Martínez, Débora; Galván, Patricia; Vidal, Maria; Adamo, Barbara; Hortobagyi, Gabriel N; Baselga, José; Ciruelos, Eva.

Oncologist ; 24(7): 893-900, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30679318

20.

Immunohistochemical analysis of estrogen receptor in breast cancer with ESR1 mutations detected by hybrid capture-based next-generation sequencing.

Ross, Dara S; Zehir, Ahmet; Brogi, Edi; Konno, Fumiko; Krystel-Whittemore, Melissa; Edelweiss, Marcia; Berger, Michael F; Toy, Weiyi; Chandarlapaty, Sarat; Razavi, Pedram; Baselga, José; Wen, Hannah Y.

Mod Pathol ; 32(1): 81-87, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30158597

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