Detalhe da pesquisa
1.
Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Cell
; 173(2): 430-442.e17, 2018 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29606353
2.
Improving prime editing with an endogenous small RNA-binding protein.
Nature
; 628(8008): 639-647, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38570691
3.
Epitope editing enables targeted immunotherapy of acute myeloid leukaemia.
Nature
; 621(7978): 404-414, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37648862
4.
Dictys: dynamic gene regulatory network dissects developmental continuum with single-cell multiomics.
Nat Methods
; 20(9): 1368-1378, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37537351
5.
Ex vivo culture resting time impacts transplantation outcomes of genome-edited human hematopoietic stem and progenitor cells in xenograft mouse models.
Cytotherapy
; 26(6): 641-648, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38506770
6.
Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat ß-hemoglobinopathies.
Mol Ther
; 30(8): 2693-2708, 2022 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35526095
7.
Motif-Raptor: a cell type-specific and transcription factor centric approach for post-GWAS prioritization of causal regulators.
Bioinformatics
; 37(15): 2103-2111, 2021 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33532840
8.
Editing outside the body: Ex vivo gene-modification for ß-hemoglobinopathy cellular therapy.
Mol Ther
; 29(11): 3163-3178, 2021 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34628053
9.
Emerging Genetic Therapy for Sickle Cell Disease.
Annu Rev Med
; 70: 257-271, 2019 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355263
10.
Editing aberrant splice sites efficiently restores ß-globin expression in ß-thalassemia.
Blood
; 133(21): 2255-2262, 2019 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30704988
11.
CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML.
Nat Chem Biol
; 15(5): 529-539, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30992567
12.
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Nature
; 527(7577): 192-7, 2015 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26375006
13.
14q32 and let-7 microRNAs regulate transcriptional networks in fetal and adult human erythroblasts.
Hum Mol Genet
; 27(8): 1411-1420, 2018 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29432581
14.
DrugThatGene: integrative analysis to streamline the identification of druggable genes, pathways and protein complexes from CRISPR screens.
Bioinformatics
; 35(11): 1981-1984, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30395160
15.
A viable alternative for editor delivery.
Blood
; 142(9): 755-756, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37651157
16.
Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.
PLoS Genet
; 13(4): e1006760, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28453575
17.
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.
Genes Dev
; 26(18): 2075-87, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22929040
18.
FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity.
J Biol Chem
; 293(51): 19797-19811, 2018 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30366982
19.
Quantitative assessment of timing, efficiency, specificity and genetic mosaicism of CRISPR/Cas9-mediated gene editing of hemoglobin beta gene in rhesus monkey embryos.
Hum Mol Genet
; 26(14): 2678-2689, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28444193
20.
AmpUMI: design and analysis of unique molecular identifiers for deep amplicon sequencing.
Bioinformatics
; 34(13): i202-i210, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29949956