Detalhe da pesquisa
1.
Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus.
Antimicrob Agents Chemother
; 56(3): 1208-14, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22203589
2.
Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets.
PLoS Pathog
; 6(7): e1001015, 2010 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-20661429
3.
AS03-adjuvanted H7N9 inactivated split virion vaccines induce cross-reactive and protective responses in ferrets.
NPJ Vaccines
; 6(1): 40, 2021 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33742000
4.
The stem cell marker CD133 (prominin-1) is phosphorylated on cytoplasmic tyrosine-828 and tyrosine-852 by Src and Fyn tyrosine kinases.
Biochemistry
; 48(18): 3998-4007, 2009 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19296573
5.
Impaired tyrosine phosphorylation of membrane type 1-matrix metalloproteinase reduces tumor cell proliferation in three-dimensional matrices and abrogates tumor growth in mice.
Carcinogenesis
; 29(8): 1655-64, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18621744
6.
Delphinidin, a dietary anthocyanidin, inhibits platelet-derived growth factor ligand/receptor (PDGF/PDGFR) signaling.
Carcinogenesis
; 29(5): 1033-41, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18339683
7.
Tissue factor pathway inhibitor (TFPI) interferes with endothelial cell migration by inhibition of both the Erk pathway and focal adhesion proteins.
Thromb Haemost
; 99(3): 576-85, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18327407
8.
Proteomic analysis of human plasma proteins by two-dimensional gel electrophoresis and by antibody arrays following depletion of high-abundance proteins.
Cell Biochem Biophys
; 49(3): 182-95, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17952643
9.
VEGF increases the fibrinolytic activity of endothelial cells within fibrin matrices: involvement of VEGFR-2, tissue type plasminogen activator and matrix metalloproteinases.
Thromb Res
; 121(2): 203-12, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17512973
10.
Low hemagglutinin antigen dose influenza vaccines adjuvanted with AS03 alter the long-term immune responses in BALB/c mice.
Hum Vaccin Immunother
; 13(3): 561-571, 2017 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27768511
11.
Comparison of AS03 and Alum on immune responses elicited by A/H3N2 split influenza vaccine in young, mature and aged BALB/c mice.
Vaccine
; 34(12): 1444-51, 2016 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26873056
12.
A chimeric haemagglutinin-based influenza split virion vaccine adjuvanted with AS03 induces protective stalk-reactive antibodies in mice.
NPJ Vaccines
; 12016.
Artigo
em Inglês
| MEDLINE | ID: mdl-29250436
13.
Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets.
Influenza Other Respir Viruses
; 10(2): 122-6, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26526406
14.
The E119D neuraminidase mutation identified in a multidrug-resistant influenza A(H1N1)pdm09 isolate severely alters viral fitness in vitro and in animal models.
Antiviral Res
; 132: 6-12, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27185624
15.
Direct-acting fibrinolytic enzymes in shark cartilage extract: potential therapeutic role in vascular disorders.
Thromb Res
; 115(1-2): 143-52, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15567466
16.
The antiangiogenic agent neovastat (AE-941) inhibits vascular endothelial growth factor-mediated biological effects.
Clin Cancer Res
; 8(4): 1242-50, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11948139
17.
The antiangiogenic agent Neovastat (AE-941) induces endothelial cell apoptosis.
Mol Cancer Ther
; 1(10): 795-802, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12492112
18.
AS03-adjuvanted H7N1 detergent-split virion vaccine is highly immunogenic in unprimed mice and induces cross-reactive antibodies to emerged H7N9 and additional H7 subtypes.
Vaccine
; 33(32): 3784-7, 2015 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26100923
19.
AS03-Adjuvanted, Very-Low-Dose Influenza Vaccines Induce Distinctive Immune Responses Compared to Unadjuvanted High-Dose Vaccines in BALB/c Mice.
Front Immunol
; 6: 207, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25972874
20.
Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines.
Vaccine
; 32(43): 5730-9, 2014 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25173481