Detalhe da pesquisa
1.
Commentary: Value of information case study strongly supports use of the Threshold of Toxicological Concern (TTC).
Regul Toxicol Pharmacol
; 149: 105594, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38555099
2.
Best practices for exposure model peer review - A SciPinion advisory panel report.
Regul Toxicol Pharmacol
; 138: 105316, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36528271
3.
Quantitative Structure Use Relationships: Highlights from a technical summit meeting.
Regul Toxicol Pharmacol
; 145: 105516, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37838348
4.
The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay.
Toxicol Appl Pharmacol
; 387: 114774, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31783037
5.
Recommendations for further revisions to improve the International Agency for Research on Cancer (IARC) Monograph program.
Regul Toxicol Pharmacol
; 113: 104639, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32147291
6.
21st Century Approaches for Evaluating Exposures, Biological Activity, and Risks of Complex Substances: Workshop highlights.
Regul Toxicol Pharmacol
; 111: 104583, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31935484
7.
Development of an adverse outcome pathway for chemically induced hepatocellular carcinoma: case study of AFB1, a human carcinogen with a mutagenic mode of action.
Crit Rev Toxicol
; 48(4): 312-337, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29431554
8.
How well can carcinogenicity be predicted by high throughput "characteristics of carcinogens" mechanistic data?
Regul Toxicol Pharmacol
; 90: 185-196, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28866267
9.
Quantitative weight of evidence to assess confidence in potential modes of action.
Regul Toxicol Pharmacol
; 86: 205-220, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28232103
10.
How well can in vitro data predict in vivo effects of chemicals? Rodent carcinogenicity as a case study.
Regul Toxicol Pharmacol
; 77: 54-64, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26879462
11.
Modernizing problem formulation for risk assessment necessitates articulation of mode of action.
Regul Toxicol Pharmacol
; 72(3): 538-51, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25929618
12.
Challenges in using the ToxRefDB as a resource for toxicity prediction modeling.
Regul Toxicol Pharmacol
; 72(3): 610-4, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26003516
13.
The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor.
Regul Toxicol Pharmacol
; 73(1): 172-90, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26145830
14.
An exposure:activity profiling method for interpreting high-throughput screening data for estrogenic activity--proof of concept.
Regul Toxicol Pharmacol
; 71(3): 398-408, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25656492
15.
Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes.
Regul Toxicol Pharmacol
; 71(3): 463-77, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25707856
16.
Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence.
Regul Toxicol Pharmacol
; 72(3): 514-37, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25863193
17.
Interpreting estrogen screening assays in the context of potency and human exposure relative to natural exposures to phytoestrogens.
Birth Defects Res B Dev Reprod Toxicol
; 101(1): 114-24, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24391076
18.
Relevance weighting of tier 1 endocrine screening endpoints by rank order.
Birth Defects Res B Dev Reprod Toxicol
; 101(1): 90-113, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24510745
19.
Developing scientific confidence in HTS-derived prediction models: lessons learned from an endocrine case study.
Regul Toxicol Pharmacol
; 69(3): 443-50, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24845243
20.
Advancing human health risk assessment: integrating recent advisory committee recommendations.
Crit Rev Toxicol
; 43(6): 467-92, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23844697