Pesquisa | BVS Violência e Saúde

1.

New balance in pluripotency: reprogramming with lineage specifiers.

Ben-David, Uri; Nissenbaum, Jonathan; Benvenisty, Nissim.

Cell ; 153(5): 939-40, 2013 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-23706730

2.

Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition.

Cohen-Sharir, Yael; McFarland, James M; Abdusamad, Mai; Marquis, Carolyn; Bernhard, Sara V; Kazachkova, Mariya; Tang, Helen; Ippolito, Marica R; Laue, Kathrin; Zerbib, Johanna; Malaby, Heidi L H; Jones, Andrew; Stautmeister, Lisa-Marie; Bockaj, Irena; Wardenaar, René; Lyons, Nicholas; Nagaraja, Ankur; Bass, Adam J; Spierings, Diana C J; Foijer, Floris; Beroukhim, Rameen; Santaguida, Stefano; Golub, Todd R; Stumpff, Jason; Storchová, Zuzana; Ben-David, Uri.

Nature ; 590(7846): 486-491, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33505028

3.

CKAP5 stabilizes CENP-E at kinetochores by regulating microtubule-chromosome attachments.

Lakshmi, R Bhagya; Nayak, Pinaki; Raz, Linoy; Sarkar, Apurba; Saroha, Akshay; Kumari, Pratibha; Nair, Vishnu M; Kombarakkaran, Delvin P; Sajana, S; M G, Sanusha; Agasti, Sarit S; Paul, Raja; Ben-David, Uri; Manna, Tapas K.

EMBO Rep ; 25(4): 1909-1935, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38424231

4.

Context is everything: aneuploidy in cancer.

Ben-David, Uri; Amon, Angelika.

Nat Rev Genet ; 21(1): 44-62, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31548659

5.

Genetic and transcriptional evolution alters cancer cell line drug response.

Ben-David, Uri; Siranosian, Benjamin; Ha, Gavin; Tang, Helen; Oren, Yaara; Hinohara, Kunihiko; Strathdee, Craig A; Dempster, Joshua; Lyons, Nicholas J; Burns, Robert; Nag, Anwesha; Kugener, Guillaume; Cimini, Beth; Tsvetkov, Peter; Maruvka, Yosef E; O'Rourke, Ryan; Garrity, Anthony; Tubelli, Andrew A; Bandopadhayay, Pratiti; Tsherniak, Aviad; Vazquez, Francisca; Wong, Bang; Birger, Chet; Ghandi, Mahmoud; Thorner, Aaron R; Bittker, Joshua A; Meyerson, Matthew; Getz, Gad; Beroukhim, Rameen; Golub, Todd R.

Nature ; 560(7718): 325-330, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-30089904

6.

Immunosignatures associated with TP53 status and co-mutations classify prognostically head and neck cancer patients.

Sacconi, Andrea; Muti, Paola; Pulito, Claudio; Urbani, Giulia; Allegretti, Matteo; Pellini, Raul; Mehterov, Nikolay; Ben-David, Uri; Strano, Sabrina; Bossi, Paolo; Blandino, Giovanni.

Mol Cancer ; 22(1): 192, 2023 11 30.

Artigo em Inglês | MEDLINE | ID: mdl-38031025

7.

Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells.

Wang, Ruoxi W; Viganò, Sonia; Ben-David, Uri; Amon, Angelika; Santaguida, Stefano.

EMBO Rep ; 22(8): e52032, 2021 08 04.

Artigo em Inglês | MEDLINE | ID: mdl-34105235

8.

Genome doubling causes double trouble.

Eliezer, Yonatan; Ben-David, Uri.

Nature ; 604(7904): 44-45, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35354975

9.

Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division.

Replogle, John Michael; Zhou, Wen; Amaro, Adrianna E; McFarland, James M; Villalobos-Ortiz, Mariana; Ryan, Jeremy; Letai, Anthony; Yilmaz, Omer; Sheltzer, Jason; Lippard, Stephen J; Ben-David, Uri; Amon, Angelika.

Proc Natl Acad Sci U S A ; 117(48): 30566-30576, 2020 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-33203674

10.

Genomic instability, driver genes and cell selection: Projections from cancer to stem cells.

Ben-David, Uri.

Biochim Biophys Acta ; 1849(4): 427-35, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25132386

11.

Brief reports: Controlling the survival of human pluripotent stem cells by small molecule-based targeting of topoisomerase II alpha.

Ben-David, Uri; Cowell, Ian G; Austin, Caroline A; Benvenisty, Nissim.

Stem Cells ; 33(3): 1013-9, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25377277

12.

Elevated expression of ACE2 in tumor-adjacent normal tissues of cancer patients.

Winkler, Tom; Ben-David, Uri.

Int J Cancer ; 147(11): 3264-3266, 2020 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-32525565

13.

Machine-learning analysis reveals an important role for negative selection in shaping cancer aneuploidy landscapes.

Jubran, Juman; Slutsky, Rachel; Rozenblum, Nir; Rokach, Lior; Ben-David, Uri; Yeger-Lotem, Esti.

Genome Biol ; 25(1): 95, 2024 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-38622679

14.

Chromosome 7 to the rescue: overcoming chromosome 10 loss in gliomas.

Nair, Nishanth Ulhas; Schäffer, Alejandro A; Gertz, E Michael; Cheng, Kuoyuan; Zerbib, Johanna; Sahu, Avinash Das; Leor, Gil; Shulman, Eldad D; Aldape, Kenneth D; Ben-David, Uri; Ruppin, Eytan.

bioRxiv ; 2024 Jan 22.

Artigo em Inglês | MEDLINE | ID: mdl-38313282

15.

High prevalence of evolutionarily conserved and species-specific genomic aberrations in mouse pluripotent stem cells.

Ben-David, Uri; Benvenisty, Nissim.

Stem Cells ; 30(4): 612-22, 2012 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-22328490

16.

Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations.

Chang, Tian-Gen; Cao, Yingying; Shulman, Eldad D; Ben-David, Uri; Schäffer, Alejandro A; Ruppin, Eytan.

NPJ Precis Oncol ; 7(1): 54, 2023 Jun 03.

Artigo em Inglês | MEDLINE | ID: mdl-37270587

17.

Acute expression of human APOBEC3B in mice results in RNA editing and lethality.

Alonso de la Vega, Alicia; Temiz, Nuri Alpay; Tasakis, Rafail; Somogyi, Kalman; Salgueiro, Lorena; Zimmer, Eleni; Ramos, Maria; Diaz-Jimenez, Alberto; Chocarro, Sara; Fernández-Vaquero, Mirian; Stefanovska, Bojana; Reuveni, Eli; Ben-David, Uri; Stenzinger, Albrecht; Poth, Tanja; Heikenwälder, Mathias; Papavasiliou, Nina; Harris, Reuben S; Sotillo, Rocio.

Genome Biol ; 24(1): 267, 2023 Nov 24.

Artigo em Inglês | MEDLINE | ID: mdl-38001542

18.

Short-term molecular consequences of chromosome mis-segregation for genome stability.

Garribba, Lorenza; De Feudis, Giuseppina; Martis, Valentino; Galli, Martina; Dumont, Marie; Eliezer, Yonatan; Wardenaar, René; Ippolito, Marica Rosaria; Iyer, Divya Ramalingam; Tijhuis, Andréa E; Spierings, Diana C J; Schubert, Michael; Taglietti, Silvia; Soriani, Chiara; Gemble, Simon; Basto, Renata; Rhind, Nick; Foijer, Floris; Ben-David, Uri; Fachinetti, Daniele; Doksani, Ylli; Santaguida, Stefano.

Nat Commun ; 14(1): 1353, 2023 03 11.

Artigo em Inglês | MEDLINE | ID: mdl-36906648

19.

Spectrum of Response to Platinum and PARP Inhibitors in Germline BRCA-Associated Pancreatic Cancer in the Clinical and Preclinical Setting.

Stossel, Chani; Raitses-Gurevich, Maria; Atias, Dikla; Beller, Tamar; Glick Gorman, Yulia; Halperin, Sharon; Peer, Eyal; Denroche, Robert E; Zhang, Amy; Notta, Faiyaz; Wilson, Julie M; O'Kane, Grainne M; Haimov Talmoud, Elina; Amison, Nora; Schvimer, Michael; Salpeter, Seth J; Bar, Vered; Zundelevich, Adi; Tirosh, Itay; Tal, Rotem; Dinstag, Gal; Kinar, Yaron; Eliezer, Yonatan; Ben-David, Uri; Gavert, Nancy S; Straussman, Ravid; Gallinger, Steven J; Berger, Raanan; Golan, Talia.

Cancer Discov ; 13(8): 1826-1843, 2023 08 04.

Artigo em Inglês | MEDLINE | ID: mdl-37449843

20.

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling.

Altea-Manzano, Patricia; Doglioni, Ginevra; Liu, Yawen; Cuadros, Alejandro M; Nolan, Emma; Fernández-García, Juan; Wu, Qi; Planque, Mélanie; Laue, Kathrin Julia; Cidre-Aranaz, Florencia; Liu, Xiao-Zheng; Marin-Bejar, Oskar; Van Elsen, Joke; Vermeire, Ines; Broekaert, Dorien; Demeyer, Sofie; Spotbeen, Xander; Idkowiak, Jakub; Montagne, Aurélie; Demicco, Margherita; Alkan, H Furkan; Rabas, Nick; Riera-Domingo, Carla; Richard, François; Geukens, Tatjana; De Schepper, Maxim; Leduc, Sophia; Hatse, Sigrid; Lambrechts, Yentl; Kay, Emily Jane; Lilla, Sergio; Alekseenko, Alisa; Geldhof, Vincent; Boeckx, Bram; de la Calle Arregui, Celia; Floris, Giuseppe; Swinnen, Johannes V; Marine, Jean-Christophe; Lambrechts, Diether; Pelechano, Vicent; Mazzone, Massimiliano; Zanivan, Sara; Cools, Jan; Wildiers, Hans; Baud, Véronique; Grünewald, Thomas G P; Ben-David, Uri; Desmedt, Christine; Malanchi, Ilaria; Fendt, Sarah-Maria.

Nat Cancer ; 4(3): 344-364, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36732635

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