RESUMO
OBJECTIVES: To calculate the hepatitis B surface antigen (HBsAg) reactive rate for 2011 blood donors (BD) across Morocco. In addition, to monitor the profile of donors bearing the HBsAg during 2000 and 2011, we calculated the percentage of the prevalence in both sexes, in different age groups and in first-time replacement and regular BD from the Rabat Regional Blood Transfusion Centre. BACKGROUND: Hepatitis B is a viral infection that spreads through blood and other biological fluids. The hepatitis B virus remains one of the most common serious complications of transfusion. No information exists on the real prevalence of hepatitis B in Moroccan BD. METHODS: For the 2011 national HBsAg reactive rate, the percentage was calculated based on enzyme-linked immunosorbent assay (ELISA) results of the 232 190 blood donations collected around the country. For the Rabat blood Centre, we calculated the hepatitis B sero-prevalence from donations made at the donors' suite during 2000 and 2011. RESULTS: The national prevalence of HBsAg was 1·34%. The HBsAg variations among different regions was between 0·43 and 2·86%. The Rabat donors' suite hepatitis B prevalence decreased from 2·47% in 2000 to 0·91% in 2011 (P < 0·001). In both years, family/replacement donors were found as safe as first-time BD and female donors were the safest. CONCLUSIONS: These results, presented for the first time in the country, mapped the hepatitis B distribution across Morocco in a healthy population. The findings of this study could be of great importance in setting up strategies for the recruitment of the BD and keeping blood safety at the highest level.
Assuntos
Doadores de Sangue , Transfusão de Sangue , Antígenos de Superfície da Hepatite B/sangue , Hepatite B , Adolescente , Adulto , Feminino , Hepatite B/sangue , Hepatite B/epidemiologia , Hepatite B/transmissão , Humanos , Masculino , Marrocos/epidemiologia , Estudos Retrospectivos , Estudos SoroepidemiológicosAssuntos
Armazenamento de Sangue/métodos , Fatores de Coagulação Sanguínea/normas , Segurança do Sangue/normas , Transfusão de Sangue/métodos , Fracionamento Químico/métodos , Plasma/química , Bancos de Sangue/economia , Transfusão de Sangue/normas , Hemofilia A/tratamento farmacológico , Hemofilia B/tratamento farmacológico , Humanos , Marrocos , Preparações Farmacêuticas/normas , Estudos RetrospectivosRESUMO
The aim of this research is to search for the distribution of blood groups in all the regions of Morocco. This study, done for the first time, aimed to provide the frequency of the Rhesus system and Kell (K) in more than 55000 blood donors from nine different regions around the country. In addition, the frequency of the Cellano, Duffy, Kidd, and MNS blood antigens was searched for 500 blood donors from the Rabat's region. Frequency of blood donors with rare blood groups was characterized for the first time in the country and compared to results found from other populations.