Detalhe da pesquisa
1.
Stromal Microenvironment Shapes the Intratumoral Architecture of Pancreatic Cancer.
Cell
; 178(1): 160-175.e27, 2019 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31155233
2.
A Landscape of Pharmacogenomic Interactions in Cancer.
Cell
; 166(3): 740-754, 2016 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27397505
3.
Effective drug combinations in breast, colon and pancreatic cancer cells.
Nature
; 603(7899): 166-173, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197630
4.
ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.
Genes Dev
; 31(3): 318-332, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28242626
5.
Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN-amplified neuroblastoma.
Proc Natl Acad Sci U S A
; 118(13)2021 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33762304
6.
Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase.
Mol Cell
; 59(6): 1011-24, 2015 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26365377
7.
Author Correction: MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG.
Nat Chem Biol
; 15(12): 1249, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31645751
8.
BRAF and AXL oncogenes drive RIPK3 expression loss in cancer.
PLoS Biol
; 16(8): e2005756, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30157175
9.
Radioresistance of KRAS/TP53-mutated lung cancer can be overcome by radiation dose escalation or EGFR tyrosine kinase inhibition in vivo.
Int J Cancer
; 147(2): 472-477, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31359406
10.
Simultaneous Detection of Gene Fusions and Base Mutations in Cancer Tissue Biopsies by Sequencing Dual Nucleic Acid Templates in Unified Reaction.
Clin Chem
; 66(1): 178-187, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31810998
11.
MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG.
Nat Chem Biol
; 14(11): 1032-1042, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30297875
12.
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.
Nature
; 511(7511): 616-20, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25043025
13.
Statistical assessment and visualization of synergies for large-scale sparse drug combination datasets.
BMC Bioinformatics
; 20(1): 83, 2019 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30777010
14.
A common Chk1-dependent phenotype of DNA double-strand break suppression in two distinct radioresistant cancer types.
Breast Cancer Res Treat
; 174(3): 605-613, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30607635
15.
Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer.
Proc Natl Acad Sci U S A
; 112(11): E1288-96, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25737542
16.
PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1.
Proc Natl Acad Sci U S A
; 110(52): 21124-9, 2013 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24327733
17.
Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients.
Proc Natl Acad Sci U S A
; 110(9): 3483-8, 2013 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23378636
18.
Drug/Cell-line Browser: interactive canvas visualization of cancer drug/cell-line viability assay datasets.
Bioinformatics
; 30(22): 3289-90, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25100688
19.
Phase II study of olaparib in patients with refractory Ewing sarcoma following failure of standard chemotherapy.
BMC Cancer
; 14: 813, 2014 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25374341
20.
PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors.
Nat Cancer
; 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38637658