Detalhe da pesquisa
1.
Biomarker Qualification for Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: Theory and Practice.
Ann Neurol
; 95(2): 211-216, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110839
2.
G2C4 targeting antisense oligonucleotides potently mitigate TDP-43 dysfunction in human C9orf72 ALS/FTD induced pluripotent stem cell derived neurons.
Acta Neuropathol
; 147(1): 1, 2023 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38019311
3.
Continuous Commitment: Long-Term Care RNs' Experience Communicating With Residents and Their Families About End-of-Life Care Preferences.
J Gerontol Nurs
; 48(11): 29-36, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36286502
4.
End-Of-Life Care Communication in Long-Term Care Among Nurses, Residents, and Families: A Critical Review of Qualitative Research.
J Gerontol Nurs
; 47(7): 43-49, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34191654
5.
Late-Stage 18 O Labeling of Primary Sulfonamides via a Degradation-Reconstruction Pathway.
Chemistry
; 26(19): 4251-4255, 2020 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32003092
6.
Long-Term Care Nurses and Their Experiences With Patients' and Families' End-of-Life Preferences: A Focus Group Study.
J Gerontol Nurs
; 46(12): 23-29, 2020 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33232494
7.
Concise syntheses and HCV NS5B polymerase inhibition of (2'R)-3 and (2'S)-2'-ethynyluridine-10 and related nucleosides.
Bioorg Med Chem Lett
; 27(23): 5349-5352, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29056248
8.
Optimization of potency and pharmacokinetics of tricyclic indole derived inhibitors of HCV NS5B polymerase. Identification of ester prodrugs with improved oral pharmacokinetics.
Bioorg Med Chem
; 22(1): 447-58, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24275348
9.
Structure Guided Discovery of Novel Pan Metallo-ß-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration.
J Med Chem
; 67(5): 3400-3418, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38387069
10.
Discovery of an irreversible HCV NS5B polymerase inhibitor.
Bioorg Med Chem Lett
; 23(24): 6585-7, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24252545
11.
Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymerase.
Bioorg Med Chem
; 21(7): 2007-17, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23434368
12.
Pyridofuran substituted pyrimidine derivatives as HCV replication (replicase) inhibitors.
Bioorg Med Chem Lett
; 22(15): 5144-9, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22814211
13.
II. Novel HCV NS5B polymerase inhibitors: discovery of indole C2 acyl sulfonamides.
Bioorg Med Chem Lett
; 22(1): 713-7, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22104146
14.
Synthesis and SAR of geminal substitutions at the C5' carbosugar position of pyrimidine-derived HCV inhibitors.
Bioorg Med Chem Lett
; 22(22): 6967-73, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23036957
15.
Synthesis and SAR of pyridothiazole substituted pyrimidine derived HCV replication inhibitors.
Bioorg Med Chem Lett
; 22(17): 5652-7, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22858143
16.
5-Benzothiazole substituted pyrimidine derivatives as HCV replication (replicase) inhibitors.
Bioorg Med Chem Lett
; 22(9): 3229-34, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22472692
17.
Enhanced Delivery of Ligand-Conjugated Antisense Oligonucleotides (C16-HA-ASO) Targeting Dystrophia Myotonica Protein Kinase Transcripts for the Treatment of Myotonic Dystrophy Type 1.
Hum Gene Ther
; 33(15-16): 810-820, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35794764
18.
I. Novel HCV NS5B polymerase inhibitors: discovery of indole 2-carboxylic acids with C3-heterocycles.
Bioorg Med Chem Lett
; 21(18): 5336-41, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21840715
19.
Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS.
Sci Transl Med
; 13(604)2021 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34321318
20.
The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor.
Bioorg Med Chem Lett
; 20(8): 2617-21, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20303756