RESUMO
We investigated the ultrastructure of Birbeck granules which are found in some malignant histiocytoses such as histiocytosis X, Letterer-Siwe disease, Hand-Schüller-Christian disease, eosinophilic granuloma of the bone and self-healing reticulohistiocytosis. The research is based on the systemic study of Birbeck granules, from their formation to intracytoplasmic development, examining with the electron microscope at regular intervals ultrathin sections derived from biopsies of two cases of Langerhans cell histiocytosis.
Assuntos
Grânulos Citoplasmáticos/ultraestrutura , Histiocitose de Células de Langerhans/patologia , Células de Langerhans/ultraestrutura , Adolescente , Adulto , Evolução Biológica , Feminino , Humanos , MasculinoAssuntos
Síndrome da Imunodeficiência Adquirida/complicações , Anemia Hemolítica/induzido quimicamente , Ceftriaxona/efeitos adversos , Cefalosporinas/efeitos adversos , HIV-1 , Hemólise/efeitos dos fármacos , Ceftriaxona/administração & dosagem , Cefalosporinas/administração & dosagem , Criança , Evolução Fatal , Humanos , Infusões Intravenosas , MasculinoRESUMO
Two children with extensive ileal resection are reported. They developed gross haematuria of "non-glomerular origin", without stones or nephrocalcinosis. Previous reports indicate that acquired hyperoxaluria is common in children with a variety of intestinal disorders. Our patients had hyperoxaluria. We think that hyperoxaluria may be the cause of haematuria through a pathogenetic mechanism similar to the one ascribed to haematuria secondary to hypercalciuria and hyperuricosuria.
Assuntos
Hematúria/etiologia , Hiperoxalúria/etiologia , Adolescente , Pré-Escolar , Feminino , Humanos , Hiperoxalúria/complicações , Íleo/cirurgia , Masculino , Complicações Pós-Operatórias/etiologiaRESUMO
Renal clearances of transeferrin, IgG and C'3 were determined by the immunodiffusion method in 51 healthy children. Statistical elaboration shows the great dispersion around the mean values. The results of other Authors in healthy adults are confirmed.