Detalhe da pesquisa
1.
Selective homing of CAR-CIK cells to the bone marrow niche enhances control of the acute myeloid leukemia burden.
Blood
; 141(21): 2587-2598, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36787509
2.
dCas9-Based Scn1a Gene Activation Restores Inhibitory Interneuron Excitability and Attenuates Seizures in Dravet Syndrome Mice.
Mol Ther
; 28(1): 235-253, 2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31607539
3.
Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease.
Neurobiol Dis
; 139: 104818, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32087289
4.
AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy.
Mol Ther
; 25(12): 2727-2742, 2017 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28882452
5.
Targeting ß-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's disease.
Proc Natl Acad Sci U S A
; 112(19): E2517-26, 2015 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25918399
6.
Striatal NELF-mediated RNA polymerase II stalling controls L-dopa induced dyskinesia.
Neurobiol Dis
; 85: 93-98, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26480869
7.
Genetic and pharmacological evidence that endogenous nociceptin/orphanin FQ contributes to dopamine cell loss in Parkinson's disease.
Neurobiol Dis
; 89: 55-64, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26804029
8.
D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly.
Neurobiol Dis
; 78: 77-87, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25766677
9.
New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets.
iScience
; 27(5): 109777, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38711458
10.
SETD5 haploinsufficiency affects mitochondrial compartment in neural cells.
Mol Autism
; 14(1): 20, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37264456
11.
In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to L-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels.
Neurobiol Dis
; 45(1): 573-82, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22001605
12.
Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome.
Nat Commun
; 13(1): 161, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35013317
13.
A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development.
Sci Adv
; 8(31): eabn3986, 2022 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35921410
14.
Amantadine attenuates levodopa-induced dyskinesia in mice and rats preventing the accompanying rise in nigral GABA levels.
J Neurochem
; 118(6): 1043-55, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21740438
15.
Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity.
Nat Commun
; 12(1): 6237, 2021 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34716339
16.
Further evidence for an involvement of nociceptin/orphanin FQ in the pathophysiology of Parkinson's disease: a behavioral and neurochemical study in reserpinized mice.
J Neurochem
; 115(6): 1543-55, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20950413
17.
Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses.
Cell Rep
; 29(13): 4646-4656.e4, 2019 12 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31875567
18.
Pharmacological Inhibition of Necroptosis Protects from Dopaminergic Neuronal Cell Death in Parkinson's Disease Models.
Cell Rep
; 22(8): 2066-2079, 2018 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29466734
19.
Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson's disease.
Sci Rep
; 7(1): 7495, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790323
20.
Author Correction: Microglia-specific overexpression of α-synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity.
Nat Commun
; 12(1): 7359, 2021 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34916524