Detalhe da pesquisa
1.
International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023.
Pharmacol Rev
; 75(6): 1233-1318, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37586884
2.
Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function.
Circulation
; 149(3): 227-250, 2024 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961903
3.
A Synthetic ERR Agonist Alleviates Metabolic Syndrome.
J Pharmacol Exp Ther
; 388(2): 232-240, 2024 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37739806
4.
Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney.
Am J Pathol
; 193(12): 1969-1987, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37717940
5.
Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity.
Bioorg Chem
; 119: 105554, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923243
6.
RORγ regulates the NLRP3 inflammasome.
J Biol Chem
; 294(1): 10-19, 2019 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455347
7.
Modulation of estrogen-related receptors subtype selectivity: Conversion of an ERRß/γ selective agonist to ERRα/ß/γ pan agonists.
Bioorg Chem
; 102: 104079, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32683181
8.
Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice.
Gastroenterology
; 154(5): 1449-1464.e20, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29277561
9.
Estrogen-related receptor α decreases RHOA stability to induce orientated cell migration.
Proc Natl Acad Sci U S A
; 111(42): 15108-13, 2014 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288732
10.
Suppression of atherosclerosis by synthetic REV-ERB agonist.
Biochem Biophys Res Commun
; 460(3): 566-71, 2015 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25800870
11.
Fluorescent push-pull pH-responsive probes for ratiometric detection of intracellular pH.
Org Biomol Chem
; 12(22): 3641-8, 2014 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24756609
12.
Synthetic ERRα/ß/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity.
ACS Chem Biol
; 18(4): 756-771, 2023 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36988910
13.
Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915.
Eur J Med Chem
; 258: 115582, 2023 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37421886
14.
Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH.
Metabolites
; 12(3)2022 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35323681
15.
Thyroid hormone receptor beta (TRbeta) and liver X receptor (LXR) regulate carbohydrate-response element-binding protein (ChREBP) expression in a tissue-selective manner.
J Biol Chem
; 285(36): 28156-63, 2010 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-20615868
16.
Rev-erbα heterozygosity produces a dose-dependent phenotypic advantage in mice.
PLoS One
; 15(5): e0227720, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407314
17.
A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells.
ACS Chem Biol
; 15(9): 2338-2345, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32897058
18.
The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids.
Cell Chem Biol
; 27(10): 1272-1284.e4, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32763139
19.
Doubled lifespan and patient-like pathologies in progeria mice fed high-fat diet.
Aging Cell
; 18(1): e12852, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30548460
20.
Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells.
Sci Immunol
; 4(40)2019 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586012