Detalhe da pesquisa
1.
Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo.
Int J Cancer
; 144(8): 1983-1995, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30230537
2.
Characterization of distinct immunophenotypes across pediatric brain tumor types.
J Immunol
; 191(9): 4880-8, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24078694
3.
MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma.
J Biol Chem
; 288(3): 1918-28, 2013 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23212916
4.
Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.
Mol Cancer
; 13: 72, 2014 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24661910
5.
Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma.
Acta Neuropathol
; 127(5): 731-45, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24240813
6.
Increased immune gene expression and immune cell infiltration in high-grade astrocytoma distinguish long-term from short-term survivors.
J Immunol
; 189(4): 1920-7, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22802421
7.
Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells.
J Neurooncol
; 111(2): 113-21, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23138228
8.
Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes.
Pediatr Blood Cancer
; 60(7): 1095-102, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382118
9.
Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.
BMC Cancer
; 12: 80, 2012 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22390279
10.
Pediatric brainstem gangliogliomas show overexpression of neuropeptide prepronociceptin (PNOC) by microarray and immunohistochemistry.
Pediatr Blood Cancer
; 59(7): 1173-9, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22706982
11.
Survey of MicroRNA expression in pediatric brain tumors.
Pediatr Blood Cancer
; 56(2): 211-6, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21157891
12.
Immune gene and cell enrichment is associated with a good prognosis in ependymoma.
J Immunol
; 183(11): 7428-40, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19917695
13.
Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma.
Blood
; 112(3): 822-9, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18483394
14.
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Cell Rep
; 33(3): 108286, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33086074
15.
Targeting Polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor.
Oncotarget
; 8(57): 97290-97303, 2017 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29228610
16.
Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors.
Elife
; 62017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28094001
17.
Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma.
Oncotarget
; 7(33): 53881-53894, 2016 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27449089
18.
Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.
Cancer Cell
; 30(6): 891-908, 2016 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27960086
19.
Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma.
Cancer Immunol Res
; 3(10): 1165-74, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25968456
20.
Identification of targets for rational pharmacological therapy in childhood craniopharyngioma.
Acta Neuropathol Commun
; 3: 30, 2015 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25990246