Detalhe da pesquisa
1.
Cerebrospinal fluid mutant huntingtin is a biomarker for huntingtin lowering in the striatum of Huntington disease mice.
Neurobiol Dis
; 166: 105652, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143966
2.
Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease.
Nucleic Acids Res
; 48(1): 36-54, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31745548
3.
Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein A-I nanodisks.
J Control Release
; 360: 913-927, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37468110
4.
Reliable Resolution of Full-Length Huntingtin Alleles by Quantitative Immunoblotting.
J Huntingtons Dis
; 10(3): 355-365, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34092649
5.
Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies.
Lancet Neurol
; 19(11): 930-939, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33098802