Detalhe da pesquisa
1.
Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.
Proc Natl Acad Sci U S A
; 118(26)2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34172583
2.
Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb.
Proc Natl Acad Sci U S A
; 112(24): 7551-6, 2015 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26034288
3.
Deciphering CD137 (4-1BB) signaling in T-cell costimulation for translation into successful cancer immunotherapy.
Eur J Immunol
; 46(3): 513-22, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26773716
4.
Anti-CD137 monoclonal antibodies and adoptive T cell therapy: a perfect marriage?
Cancer Immunol Immunother
; 65(5): 493-7, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26970765
5.
Low-dose ionizing γ-radiation elicits the extrusion of neutrophil extracellular traps.
Clin Cancer Res
; 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38630754
6.
Pilot clinical trial of type 1 dendritic cells loaded with autologous tumor lysates combined with GM-CSF, pegylated IFN, and cyclophosphamide for metastatic cancer patients.
J Immunol
; 187(11): 6130-42, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22048768
7.
Interleukin-18 in cancer immunology and immunotherapy.
Expert Opin Ther Targets
; 27(11): 1035-1042, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37993172
8.
Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-ß antagonists.
Mol Ther Nucleic Acids
; 33: 668-682, 2023 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37650116
9.
mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy.
Cell Rep Med
; : 100978, 2023 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36933554
10.
Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimetic.
Oncoimmunology
; 12(1): 2197370, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37035637
11.
Intratumoral Gene Transfer of mRNAs Encoding IL12 in Combination with Decoy-Resistant IL18 Improves Local and Systemic Antitumor Immunity.
Cancer Immunol Res
; 11(2): 184-198, 2023 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36478221
12.
Intratumoral injection of IL-12-encoding mRNA targeted to CSFR1 and PD-L1 exerts potent anti-tumor effects without substantial systemic exposure.
Mol Ther Nucleic Acids
; 33: 599-616, 2023 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37637207
13.
Advances in mRNA-based drug discovery in cancer immunotherapy.
Expert Opin Drug Discov
; 17(1): 41-53, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34496689
14.
Novel strategies exploiting interleukin-12 in cancer immunotherapy.
Pharmacol Ther
; 239: 108189, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35430292
15.
A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα, and IL-1ß.
Cancer Discov
; 12(9): 2140-2157, 2022 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35771565
16.
Synergistic effects of CTLA-4 blockade with tremelimumab and elimination of regulatory T lymphocytes in vitro and in vivo.
Int J Cancer
; 129(2): 374-86, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20853321
17.
Characterization of herpes simplex virus 1 strains as platforms for the development of oncolytic viruses against liver cancer.
Liver Int
; 31(10): 1542-53, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22093330
18.
CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation.
Nat Commun
; 12(1): 7296, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34911975
19.
Engineering bionic T cells: signal 1, signal 2, signal 3, reprogramming and the removal of inhibitory mechanisms.
Cell Mol Immunol
; 17(6): 576-586, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32433539
20.
Exploiting TCR Recognition of Shared Hotspot Oncogene-encoded Neoantigens.
Clin Cancer Res
; 26(6): 1203-1204, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32001482