Topology of megagauss magnetic fields and of heat-carrying electrons produced in a high-power laser-solid interaction.

The intricate spatial and energy distribution of magnetic fields, self-generated during high power laser irradiation (at Iλ^{2}∼10^{13}-10^{14} W.cm^{-2}.µm^{2}) of a solid target, and of the heat-carrying electron currents, is studied in inertial confinement fusion (ICF) relevant conditions. This is done by comparing proton radiography measurements of the fields to an improved magnetohydrodynamic description that fully takes into account the nonlocality of the heat transport. We show that, in these conditions, magnetic fields are rapidly advected radially along the target surface and compressed over long time scales into the dense parts of the target. As a consequence, the electrons are weakly magnetized in most parts of the plasma flow, and we observe a reemergence of nonlocality which is a crucial effect for a correct description of the energetics of ICF experiments.

Paediatric epidemiology of Pasteurella multocida meningitis in France and review of the literature.

We report on six cases of Pasteurella multocida (P. multocida) meningitis occurring between 2001 and 2011 by a French nationwide active surveillance network of paediatric bacterial meningitis (ACTIV/GPIP). The cases accounted for 0.15 % of the paediatric meningitis cases reported between 2001 and 2011 in France, all in infants <4 months old. A review of the literature allowed us to gather information on 42 other cases of P. multocida meningitis in infants <1 year old reported since 1963. Among all 48 cases, 44 % were newborns. An animal source of the infection, including 39 household dogs and cats, was suspected or identified in 42 of 48 cases. A traumatic contact between the child and a pet occurred in 8 % of cases, and a vertical transmission from mother to child during birth in 10.4 %. Most of the time, the infection resulted from non-traumatic contact between the child and the pet, through licking or sniffing. The absence of host risk factors suggests that an immature immune system is responsible, given the young age of the children. Although complications, especially neurological lesions, were not rare (37.5 %), the long-term outcome was usually good. Four infants died of meningitis. This rare disease could be prevented by reducing contact between infants and household pets, and by performing simple hygiene measures before handling babies.

A Five-Year Review of Feto-Maternal Outcome of Antepartum Haemorrhage in a Tertiary Center.

Background: Pregnancies complicated with antepartum-haemorrhage is high risk pregnancies associated with adverse maternal, fetal-and-perinatal-outcomes. It contributes significantly to fetal and maternal mortality especially in the developing countries. Proper antenatal care and prompt intervention is necessary to forestall adverse and improve outcome. Objective: To determine the prevalence, sociodemographic characteristics, risk factors, fetomaternal outcome of pregnancies with antepartum haemorrhage. Methods: The case files of the patients were retrieved from the medical records department. The total number of deliveries within the study period was obtained from the labour ward records. The feto-maternal-outcome-measures were; prevalence of caesarean-section, postpartum-haemorrhage, hysterectomy, need for blood-transfusion, maternal-death, prematurity, need for admission in intensive-care-unit and still births. The data was analysed using SPSS version 21. Chi-square was used to test for significance. Results: Within the 5-year period under review, out of a total of 6974 deliveries, 234 had antepartum-haemorrhage (3.4% prevalence rate). Abruptio-placentae was the commonest cause and accounted for 69.5% of the cases (prevalence of 2.1%) while placenta praevia accounted for 28.2% of the cases (prevalence rate of 0.9%). The mean age of the women was 31.8±5.3 years. The mean parity was 3.4±1.7 and majority (63.8%) of the women were unbooked. The commonest identifiable risk factors were multiparity and advanced maternal age. One-hundred-and sixty-six (77.9%) women were delivered through the abdominal route. Postpartum-haemorrhage occurred in 22.1% (47) of the cases while prematurity was the commonest fetal complications. Maternal mortality was 0.47% (1) while still birth was 44.1% (94). Conclusion: There is high prevalence of antepartum-haemorrhage in our environment. Abruptio-placentae was the commonest cause and associated with significant adverse fetomaternal-outcome when compared with placenta-praevia. Thus, good and quality antenatal care as well as high index of suspicion, prompt diagnosis and treatment remain the key to forestall these complications and improve fetomaternal-outcome.

A randomized clinical trial of Premaquick biomarkers versus transvaginal cervical length for pre-induction cervical assessment at term among pregnant women.

Objectives: To compare Premaquick biomarkers (combined insulin-like growth-factor binding protein 1 and interleukin-6) and cervical length measurement via transvaginal ultrasound for pre-induction cervical evaluation at term among pregnant women. Methods: A randomized clinical trial of consenting pregnant women at the Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria. The women were randomized equally into Premaquick group (n = 36) and transvaginal ultrasound group (n = 36). The cervix was adjudged 'ripe' if the Premaquick test was positive or if the trans-vaginal measured cervical length was less than 28 mm. The primary outcome measures were the proportions of women who needed prostaglandin analogue for cervical ripening and the proportion that achieved vaginal delivery after induction of labour. The trial was registered in Pan African clinical trial registry (PACTR) registry with approval number PACTR202001579275333. Results: The baseline characteristics were similar between the two groups (p > 0.05). There was no statistically significant difference between the two groups in terms of proportion of women that required prostaglandins for pre-induction cervical ripening (41.7 versus 47.2%, p = 0.427), vaginal delivery (77.8 versus 80.6%, p = 0.783), mean induction to delivery interval (22.9 ± 2.81 h versus 24.04 ± 3.20 h, p = 0.211), caesarean delivery (22.2 versus 19.4%, p = 0.783), proportion of neonate with birth asphyxia (8.30 versus 8.30%, p = 1.00) and proportion of neonate admitted into special care baby unit (16.7 versus 13.9%, p = 0.872). Subgroup analysis of participants with 'ripe' cervix at initial pre-induction assessment showed that the mean induction to active phase of labour interval and mean induction to delivery interval were significantly shorter in Premaquick than transvaginal ultrasound group. Conclusion: Pre-induction cervical assessment at term with either Premaquick biomarkers or transvaginal ultrasound for cervical length is effective, objective and safe with similar and comparable outcome. However, when compared with women with positive transvaginal ultrasound at initial assessment, women with positive Premaquick test at initial assessment showed a significantly shorter duration of onset of active phase of labour and delivery of baby following induction of labour.

Identifying Gaps in Population Health Nursing Educational Resources Through a Culture of Health Initiative Project.

BACKGROUND: To meet the health care challenges and increasing population health demands of today and the future, the Missouri Center for Nursing developed the Culture of Health Initiative Project (CHIP). METHOD: Phase one surveys examined 33 nurse leaders' responses to the population health knowledge and training needs of nurses in their organizations. In phase two, 71 nurse leaders' and practicing nurses' responses from the Population Health Nursing Skills Survey provided insight into the education needs of Missouri nurses. RESULTS: Findings identified a lack of available education and resources related to nursing, limited knowledge of concepts among nursing leaders, and a need for flexibility in the format and content to educate nurses in all types of nursing practice. CONCLUSION: Professional development practitioners must collaborate with nurses and nurse leaders, in all settings, to meet the learning needs necessary for Culture of Health competence. [J Contin Educ Nurs. 2020;51(12):568-573.].

Arch index as a predictor of pes planus: a comparative study of indigenous Kenyans and Tanzanians.

We determined the arch index of able-bodied indigenous Kenyan and Tanzanian individuals free of foot pain by using their dynamic footprints to classify the foot arch type and determine the prevalence of pes planus according to a previously described method. Males had a significantly higher arch index than females in both groups, and the prevalence of pes planus in Kenyans was 432 per 1,000 population, the highest ever documented and twice as high as that in Tanzanians (203 per 1,000 population). The arch index is useful in determining the prevalence of pes planus and possibly predicting pathologic foot conditions, and it may serve as an early warning sign of structural and functional defects of the foot in a given population.

The femoral collodiaphyseal angle in Malawian adults.

We used unilateral anteroposterior radiographs to measure the collodiaphyseal angle of the hip in 368 Malawian adults--222 men and 146 women 18 to 76 years old. The angle ranged from 105 degrees to 144 degrees (mean, 121.09 degrees; SD, 7.17 degrees). Results confirmed that the angle was wider in men than in women-indicating dimorphism based on sex--but no Malawian could be identified by sex using the recommended demarking point method of Jit and Singh (1966). The importance of the angle and its usefulness to practicing orthopedic surgeons in this part of the world are emphasized.

[Takayasu's disease: interest in methotrexate treatment]. / Maladie de Takayasu: intérêt du traitement par méthotrexate.

UNLABELLED: Takayasu's disease is a nonspecific aortic arteritis that affects mostly young women and sometimes children. Usual treatment consists of early and prolonged steroids. Some patients do not respond to this treatment, become steroid-dependent or suffer from side effects. We report a case in which methotrexate proved to be effective. CASE REPORT: A 6-year-old girl presented with Takayasu's disease with elevated blood pressure of renovascular origin. Corticosteroids controlled the inflammatory syndrome but not the renal involvement and stopped the growth. Methotrexate (10 mg/m2/week) resulted in the control of the disease, the reduction of steroids and normal growth. CONCLUSION: In Takayasu's disease, steroids should be given as first-line therapy. In case of failure, side effects or steroid dependency, small doses of methotrexate may facilitate the disease's control and weaning from the steroids.

Identification and tissue distribution of rabbit leucocyte antigens recognized by monoclonal antibodies.

Three monoclonal antibodies which recognize rabbit leucocytes have been characterized by immunofluorescence staining of a variety of cell populations and also by immunochemical techniques. The evidence obtained suggests that these antibodies recognize the rabbit equivalents of the CD58/LFA-3 (VC21), CD43/leukosialin (L11/135) and CD9 (MM2/57) antigens. A fourth antibody, RPN3/57, recognizes an antigen expressed strongly on T cells, thymocytes and neutrophils and at lower levels on platelets. It has not, however been possible to characterize the antigen recognized by RPN3/57 in molecular terms. Both L11/135 and RPN3/57 are useful reagents for the detection of T cells both by flow cytometry and by immunohistochemistry.

[Evaluation of the search for soluble antigens in the cerebrospinal fluid from 31 cases of purulent meningitis in children]. / Evaluation de la recherche des antigènes solubles dans le liquide céphalo-rachidien de 31 cas de méningites purulentes de l'enfant.

Soluble antigens were looked for in 31 cases of purulent meningitis in children aged one day to 16 years. The latex technique was used in this study. Negative cases were controlled by counter-immune electrophoresis and by ELISA. From the results of our study and after a review of the literature, it appears that the latex technique is the best method at present to identify soluble antigens in purulent meningitis. This technique is better than a direct microscopic examination (p less than 0.02), especially in cases of meningitis due to H. influenzae and to S. pneumoniae. Latex technique kits used in the identification of type B meningococcus should be improved, and additional kits are needed if a wider range of bacteria are to be identified.

Palmar and digital dermatoglyphics of indigenous black Zimbabweans.

BACKGROUND: Dermatoglyphic traits have been shown to be genetically determined, conservative in their evolution, and different between and within population groups. There have been a few reports dealing with Southern African populations, but there appears to be no published report for indigenous black Zimbabweans. MATERIAL/METHODS: Bilateral palmar and digital prints of 270 indigenous black Zimbabweans were recorded, studied and classified using standard methods. The total finger ridge count (TFRC), pattern intensity index (PII), atd angle, and a-b ridge counts were analyzed and the data compared with those of Malawians, South African Zulus and Nigerian Yorubas. RESULTS: Ulnar loops were the most predominant digital pattern type in both sexes followed by whorls in males and arches in females. Females had significantly higher atd angles than males (p<0.01). Significant differences were also demonstrated between Zimbabwean and Malawian females, and between Zimbabwean and Yoruba men in TFRC and a-b ridge counts. Similarly significant differences were observed between Zimbabwean and Malawian males, male Zimbabweans and Yoruba, and male Zulus and Yorubas in atd angle and a-b ridge counts (p<0.001). CONCLUSIONS: This study documents similarities in digital ridge patterns between Zimbabweans, Malawians, and to some extent South African Zulus, indicating their close historical and anthropological relationship. However, Zimbabweans could be differentiated from the other population groups using certain dermatoglyphic traits. Nevertheless, all the groups showed some features common to other black Africans.