Detalhe da pesquisa
1.
Synthesis of Novel Acyl Derivatives of 3-(4,5,6,7-Tetrabromo-1H-benzimidazol-1-yl)propan-1-ols-Intracellular TBBi-Based CK2 Inhibitors with Proapoptotic Properties.
Int J Mol Sci
; 22(12)2021 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34200807
2.
A competition between hydrophobic and electrostatic interactions in protein-ligand systems. Binding of heterogeneously halogenated benzotriazoles by the catalytic subunit of human protein kinase CK2.
IUBMB Life
; 72(6): 1211-1219, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32162783
3.
New insight into nucleo α-amino acids - Synthesis and SAR studies on cytotoxic activity of ß-pyrimidine alanines.
Bioorg Chem
; 100: 103864, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32446118
4.
Human dihydrofolate reductase is a substrate of protein kinase CK2α.
Biochem Biophys Res Commun
; 513(2): 368-373, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30961929
5.
Potential bioisosteres of ß-uracilalanines derived from 1H-1,2,3-triazole-C-carboxylic acids.
Bioorg Chem
; 83: 500-510, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30453142
6.
Synthesis, in vitro antiproliferative activity and kinase profile of new benzimidazole and benzotriazole derivatives.
Bioorg Chem
; 72: 1-10, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28340404
7.
Synthesis of novel polybrominated benzimidazole derivatives-potential CK2 inhibitors with anticancer and proapoptotic activity.
Bioorg Med Chem
; 24(4): 735-41, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26778657
8.
Lipase-Catalyzed Kinetic Resolution of Novel Antifungal N-Substituted Benzimidazole Derivatives.
Chirality
; 28(4): 347-54, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26922853
9.
Thermodynamic parameters for binding of some halogenated inhibitors of human protein kinase CK2.
Biochem Biophys Res Commun
; 456(1): 282-7, 2015 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25450618
10.
[The specific enzyme inhibitors for potential therapeutic use]. / Specyficzne inhibitory enzymów o potencjalnym zastosowaniu terapeutycznym.
Postepy Biochem
; 61(3): 292-7, 2015.
Artigo
em Polonês
| MEDLINE | ID: mdl-26677576
11.
Chemical proteomics and functional proteomics strategies for protein kinase inhibitor validation and protein kinase substrate identification: applications to protein kinase CK2.
Biochim Biophys Acta
; 1834(7): 1352-8, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23416530
12.
Casein kinase II-mediated phosphorylation of general repressor Maf1 triggers RNA polymerase III activation.
Proc Natl Acad Sci U S A
; 108(12): 4926-31, 2011 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21383183
13.
Unbiased functional proteomics strategy for protein kinase inhibitor validation and identification of bona fide protein kinase substrates: application to identification of EEF1D as a substrate for CK2.
J Proteome Res
; 10(11): 4887-901, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21936567
14.
Enzymatic activity with an incomplete catalytic spine: insights from a comparative structural analysis of human CK2α and its paralogous isoform CK2α'.
Mol Cell Biochem
; 356(1-2): 57-65, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21739153
15.
Design and synthesis of CK2 inhibitors.
Mol Cell Biochem
; 356(1-2): 91-6, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21750983
16.
Studies on the anti-hepatitis C virus activity of newly synthesized tropolone derivatives: identification of NS3 helicase inhibitors that specifically inhibit subgenomic HCV replication.
Bioorg Med Chem
; 18(14): 5129-36, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20579888
17.
An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets.
Mol Cell Proteomics
; 7(6): 1077-88, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18258654
18.
Formylation of a metathesis-derived ansa[4]-ferrocene: a simple route to anticancer organometallics.
Dalton Trans
; 49(33): 11504-11511, 2020 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32627790
19.
Synthesis of new analogs of benzotriazole, benzimidazole and phthalimide--potential inhibitors of human protein kinase CK2.
Bioorg Med Chem
; 17(4): 1573-8, 2009 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19168362
20.
Simultaneous Inhibition of Protein Kinase CK2 and Dihydrofolate Reductase Results in Synergistic Effect on Acute Lymphoblastic Leukemia Cells.
Anticancer Res
; 39(7): 3531-3542, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31262877