Detalhe da pesquisa
1.
Mutated Toll-like receptor 9 increases Alzheimer's disease risk by compromising innate immunity protection.
Mol Psychiatry
; 2023 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37433968
2.
Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays.
J Biol Chem
; 295(12): 4001-4013, 2020 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32034092
3.
The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES.
J Biol Chem
; 291(25): 13175-93, 2016 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27129267
4.
Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.
Acta Neuropathol
; 133(5): 731-749, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28083634
5.
Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo.
Acta Neuropathol
; 131(4): 549-69, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26739002
6.
Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.
Acta Neuropathol
; 129(6): 875-94, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25862635
7.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Stem Cell Reports
; 11(2): 363-379, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30057263
8.
Using Human iPSC-Derived Neurons to Model TAU Aggregation.
PLoS One
; 10(12): e0146127, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26720731
9.
Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation.
Cell Rep
; 11(8): 1176-83, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25981034
10.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Stem Cell Reports
; 13(2): 434-435, 2019 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31412287
11.
Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule.
Proc Natl Acad Sci U S A
; 99(13): 8573-8, 2002 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-12084918