Pesquisa | BVS Violência e Saúde

1.

Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging.

Silva-Cayetano, Alyssa; Fra-Bido, Sigrid; Robert, Philippe A; Innocentin, Silvia; Burton, Alice R; Watson, Emily M; Lee, Jia Le; Webb, Louise M C; Foster, William S; McKenzie, Ross C J; Bignon, Alexandre; Vanderleyden, Ine; Alterauge, Dominik; Lemos, Julia P; Carr, Edward J; Hill, Danika L; Cinti, Isabella; Balabanian, Karl; Baumjohann, Dirk; Espeli, Marion; Meyer-Hermann, Michael; Denton, Alice E; Linterman, Michelle A.

Nat Immunol ; 24(7): 1124-1137, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37217705

2.

Tissue CD14⁺CD8⁺ T cells reprogrammed by myeloid cells and modulated by LPS.

Pallett, Laura J; Swadling, Leo; Diniz, Mariana; Maini, Alexander A; Schwabenland, Marius; Gasull, Adrià Dalmau; Davies, Jessica; Kucykowicz, Stephanie; Skelton, Jessica K; Thomas, Niclas; Schmidt, Nathalie M; Amin, Oliver E; Gill, Upkar S; Stegmann, Kerstin A; Burton, Alice R; Stephenson, Emily; Reynolds, Gary; Whelan, Matt; Sanchez, Jenifer; de Maeyer, Roel; Thakker, Clare; Suveizdyte, Kornelija; Uddin, Imran; Ortega-Prieto, Ana M; Grant, Charlotte; Froghi, Farid; Fusai, Giuseppe; Lens, Sabela; Pérez-Del-Pulgar, Sofia; Al-Akkad, Walid; Mazza, Giuseppe; Noursadeghi, Mahdad; Akbar, Arne; Kennedy, Patrick T F; Davidson, Brian R; Prinz, Marco; Chain, Benjamin M; Haniffa, Muzlifah; Gilroy, Derek W; Dorner, Marcus; Bengsch, Bertram; Schurich, Anna; Maini, Mala K.

Nature ; 614(7947): 334-342, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36697826

3.

Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19.

Burton, Alice R; Maini, Mala K.

Immunol Rev ; 299(1): 108-117, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33559128

4.

Fine needle aspirates comprehensively sample intrahepatic immunity.

Gill, Upkar S; Pallett, Laura J; Thomas, Niclas; Burton, Alice R; Patel, Amit A; Yona, Simon; Kennedy, Patrick T F; Maini, Mala K.

Gut ; 68(8): 1493-1503, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-30487267

5.

IL-2 leaves its mark in cirrhosis.

Burton, Alice R; Pallett, Laura J.

J Hepatol ; 74(3): 505-507, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33422337

6.

B cell-intrinsic changes with age do not impact antibody-secreting cell formation but delay B cell participation in the germinal centre reaction.

Lee, Jia Le; Fra-Bido, Sigrid C; Burton, Alice R; Innocentin, Silvia; Hill, Danika L; Linterman, Michelle A.

Aging Cell ; 21(9): e13692, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35980826

7.

The memory B cell response to influenza vaccination is impaired in older persons.

Burton, Alice R; Guillaume, Stephane M; Foster, William S; Wheatley, Adam K; Hill, Danika L; Carr, Edward J; Linterman, Michelle A.

Cell Rep ; 41(6): 111613, 2022 11 08.

Artigo em Inglês | MEDLINE | ID: mdl-36351385

8.

Isolation of human intrahepatic leukocytes for phenotypic and functional characterization by flow cytometry.

Kucykowicz, Stephanie; Amin, Oliver E; Burton, Alice R; Swadling, Leo; Schmidt, Nathalie M; Zakeri, Nekisa; Davies, Jessica; Aidoo-Micah, Gloryanne; Stegmann, Kerstin A; Easom, Nicholas J; Jeffery-Smith, Anna; Maini, Mala K; Pallett, Laura J.

STAR Protoc ; 3(2): 101356, 2022 06 17.

Artigo em Inglês | MEDLINE | ID: mdl-35516846

9.

SARS-CoV-2-specific memory B cells can persist in the elderly who have lost detectable neutralizing antibodies.

Jeffery-Smith, Anna; Burton, Alice R; Lens, Sabela; Rees-Spear, Chloe; Davies, Jessica; Patel, Monika; Gopal, Robin; Muir, Luke; Aiano, Felicity; Doores, Katie J; Chow, J Yimmy; Ladhani, Shamez N; Zambon, Maria; McCoy, Laura E; Maini, Mala K.

J Clin Invest ; 132(2)2022 01 18.

Artigo em Inglês | MEDLINE | ID: mdl-34843448

10.

Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections.

Chandran, Aneesh; Rosenheim, Joshua; Nageswaran, Gayathri; Swadling, Leo; Pollara, Gabriele; Gupta, Rishi K; Burton, Alice R; Guerra-Assunção, José Afonso; Woolston, Annemarie; Ronel, Tahel; Pade, Corinna; Gibbons, Joseph M; Sanz-Magallon Duque De Estrada, Blanca; Robert de Massy, Marc; Whelan, Matthew; Semper, Amanda; Brooks, Tim; Altmann, Daniel M; Boyton, Rosemary J; McKnight, Áine; Captur, Gabriella; Manisty, Charlotte; Treibel, Thomas Alexander; Moon, James C; Tomlinson, Gillian S; Maini, Mala K; Chain, Benjamin M; Noursadeghi, Mahdad.

Cell Rep Med ; 3(3): 100557, 2022 03 15.

Artigo em Inglês | MEDLINE | ID: mdl-35474751

11.

Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.

Schmidt, Nathalie M; Wing, Peter A C; Diniz, Mariana O; Pallett, Laura J; Swadling, Leo; Harris, James M; Burton, Alice R; Jeffery-Smith, Anna; Zakeri, Nekisa; Amin, Oliver E; Kucykowicz, Stephanie; Heemskerk, Mirjam H; Davidson, Brian; Meyer, Tim; Grove, Joe; Stauss, Hans J; Pineda-Torra, Ines; Jolly, Clare; Jury, Elizabeth C; McKeating, Jane A; Maini, Mala K.

Nat Commun ; 12(1): 2814, 2021 05 14.

Artigo em Inglês | MEDLINE | ID: mdl-33990561

12.

Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes.

Pallett, Laura J; Burton, Alice R; Amin, Oliver E; Rodriguez-Tajes, Sergio; Patel, Amit A; Zakeri, Nekisa; Jeffery-Smith, Anna; Swadling, Leo; Schmidt, Nathalie M; Baiges, Anna; Gander, Amir; Yu, Dominic; Nasralla, David; Froghi, Farid; Iype, Satheesh; Davidson, Brian R; Thorburn, Douglas; Yona, Simon; Forns, Xavier; Maini, Mala K.

J Exp Med ; 217(9)2020 09 07.

Artigo em Inglês | MEDLINE | ID: mdl-32602903

13.

Human Liver Memory CD8⁺ T Cells Use Autophagy for Tissue Residence.

Swadling, Leo; Pallett, Laura J; Diniz, Mariana O; Baker, Josephine M; Amin, Oliver E; Stegmann, Kerstin A; Burton, Alice R; Schmidt, Nathalie M; Jeffery-Smith, Anna; Zakeri, Nekisa; Suveizdyte, Kornelija; Froghi, Farid; Fusai, Giuseppe; Rosenberg, William M; Davidson, Brian R; Schurich, Anna; Simon, A Katharina; Maini, Mala K.

Cell Rep ; 30(3): 687-698.e6, 2020 01 21.

Artigo em Inglês | MEDLINE | ID: mdl-31968246

14.

Restoring, releasing or replacing adaptive immunity in chronic hepatitis B.

Maini, Mala K; Burton, Alice R.

Nat Rev Gastroenterol Hepatol ; 16(11): 662-675, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31548710

15.

The memory B cell response to influenza vaccination is impaired in older persons.

Burton, Alice R; Guillaume, Stephane M; Foster, William S; Wheatley, Adam K; Hill, Danika L; Carr, Edward J; Linterman, Michelle A.

Cell Rep ; 43(2): 113745, 2024 Feb 27.

Artigo em Inglês | MEDLINE | ID: mdl-38281131

16.

IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction.

Easom, Nicholas J W; Stegmann, Kerstin A; Swadling, Leo; Pallett, Laura J; Burton, Alice R; Odera, Dennis; Schmidt, Nathalie; Huang, Wei-Chen; Fusai, Giuseppe; Davidson, Brian; Maini, Mala K.

Front Immunol ; 9: 1009, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29867983

17.

Circulating and intrahepatic antiviral B cells are defective in hepatitis B.

Burton, Alice R; Pallett, Laura J; McCoy, Laura E; Suveizdyte, Kornelija; Amin, Oliver E; Swadling, Leo; Alberts, Elena; Davidson, Brian R; Kennedy, Patrick Tf; Gill, Upkar S; Mauri, Claudia; Blair, Paul A; Pelletier, Nadege; Maini, Mala K.

J Clin Invest ; 128(10): 4588-4603, 2018 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-30091725

18.

IL-2^high tissue-resident T cells in the human liver: Sentinels for hepatotropic infection.

Pallett, Laura J; Davies, Jessica; Colbeck, Emily J; Robertson, Francis; Hansi, Navjyot; Easom, Nicholas J W; Burton, Alice R; Stegmann, Kerstin A; Schurich, Anna; Swadling, Leo; Gill, Upkar S; Male, Victoria; Luong, TuVinh; Gander, Amir; Davidson, Brian R; Kennedy, Patrick T F; Maini, Mala K.

J Exp Med ; 214(6): 1567-1580, 2017 06 05.

Artigo em Inglês | MEDLINE | ID: mdl-28526759

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Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging.

Tissue CD14⁺CD8⁺ T cells reprogrammed by myeloid cells and modulated by LPS.

Human antiviral B cell responses: Emerging lessons from hepatitis B and COVID-19.

Fine needle aspirates comprehensively sample intrahepatic immunity.

IL-2 leaves its mark in cirrhosis.

B cell-intrinsic changes with age do not impact antibody-secreting cell formation but delay B cell participation in the germinal centre reaction.

The memory B cell response to influenza vaccination is impaired in older persons.

Isolation of human intrahepatic leukocytes for phenotypic and functional characterization by flow cytometry.

SARS-CoV-2-specific memory B cells can persist in the elderly who have lost detectable neutralizing antibodies.

Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections.

Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint.

Longevity and replenishment of human liver-resident memory T cells and mononuclear phagocytes.

Human Liver Memory CD8⁺ T Cells Use Autophagy for Tissue Residence.

Restoring, releasing or replacing adaptive immunity in chronic hepatitis B.

The memory B cell response to influenza vaccination is impaired in older persons.

IL-15 Overcomes Hepatocellular Carcinoma-Induced NK Cell Dysfunction.

Circulating and intrahepatic antiviral B cells are defective in hepatitis B.

IL-2^high tissue-resident T cells in the human liver: Sentinels for hepatotropic infection.