Detalhe da pesquisa
1.
A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions.
Blood
; 140(16): 1774-1789, 2022 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35714307
2.
Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.
Nature
; 557(7706): 580-584, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29769727
3.
NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy.
Proc Natl Acad Sci U S A
; 116(10): 4538-4547, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30787185
4.
Lineage restriction analyses in CHIP indicate myeloid bias for TET2 and multipotent stem cell origin for DNMT3A.
Blood
; 132(3): 277-280, 2018 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29764839
5.
DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions.
Blood
; 130(6): 753-762, 2017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28655780
6.
Concise Review: Age-Related Clonal Hematopoiesis: Stem Cells Tempting the Devil.
Stem Cells
; 36(9): 1287-1294, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29883022
7.
Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance.
Blood
; 123(11): 1720-8, 2014 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24478402
8.
The BAF53a subunit of SWI/SNF-like BAF complexes is essential for hemopoietic stem cell function.
Blood
; 120(24): 4720-32, 2012 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23018638
9.
Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results.
Nat Med
; 30(2): 443-454, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38321220
10.
Interplay between hereditary and acquired factors determines the neutrophil counts in older individuals.
Blood Adv
; 7(13): 3232-3243, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36930802
11.
Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life.
J Clin Invest
; 133(4)2023 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36787231
12.
Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity.
Sci Rep
; 11(1): 15767, 2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34344941
13.
COCO/DAND5 inhibits developmental and pathological ocular angiogenesis.
EMBO Mol Med
; 13(3): e12005, 2021 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33587337
14.
Myeloid-resident neuropilin-1 promotes choroidal neovascularization while mitigating inflammation.
EMBO Mol Med
; 13(5): e11754, 2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33876574
15.
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.
Cell Metab
; 33(4): 818-832.e7, 2021 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33548171
16.
60 Years of clonal hematopoiesis research: From X-chromosome inactivation studies to the identification of driver mutations.
Exp Hematol
; 83: 2-11, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32001340
17.
High-sensitivity C-reactive protein is associated with clonal hematopoiesis of indeterminate potential.
Blood Adv
; 4(11): 2430-2438, 2020 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32492156
18.
Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy.
Science
; 369(6506)2020 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32820093
19.
Human blood cell levels of 5-hydroxymethylcytosine (5hmC) decline with age, partly related to acquired mutations in TET2.
Exp Hematol
; 44(11): 1072-1084, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27475703
20.
Cofactor-activated phosphorylation is required for inhibition of cortical neuron differentiation by Groucho/TLE1.
PLoS One
; 4(12): e8107, 2009 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19956621