Pesquisa | BVS Violência e Saúde

1.

The impact of AI on research.

Weigel, Aubrey; Caldas, Carlos; Meyer, Axel; Morris, Samantha A.

Cell ; 185(15): 2621-2622, 2022 07 21.

Artigo em Inglês | MEDLINE | ID: mdl-35868265

2.

Predictability of B cell clonal persistence and immunosurveillance in breast cancer.

Sammut, Stephen-John; Galson, Jacob D; Minter, Ralph; Sun, Bo; Chin, Suet-Feung; De Mattos-Arruda, Leticia; Finch, Donna K; Schätzle, Sebastian; Dias, Jorge; Rueda, Oscar M; Seoane, Joan; Osbourn, Jane; Caldas, Carlos; Bashford-Rogers, Rachael J M.

Nat Immunol ; 25(5): 916-924, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38698238

3.

Cancer Treatment in the Genomic Era.

Doherty, Gary J; Petruzzelli, Michele; Beddowes, Emma; Ahmad, Saif S; Caldas, Carlos; Gilbertson, Richard J.

Annu Rev Biochem ; 88: 247-280, 2019 06 20.

Artigo em Inglês | MEDLINE | ID: mdl-30901264

4.

Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element.

Cho, Seung Woo; Xu, Jin; Sun, Ruping; Mumbach, Maxwell R; Carter, Ava C; Chen, Y Grace; Yost, Kathryn E; Kim, Jeewon; He, Jing; Nevins, Stephanie A; Chin, Suet-Feung; Caldas, Carlos; Liu, S John; Horlbeck, Max A; Lim, Daniel A; Weissman, Jonathan S; Curtis, Christina; Chang, Howard Y.

Cell ; 173(6): 1398-1412.e22, 2018 05 31.

Artigo em Inglês | MEDLINE | ID: mdl-29731168

5.

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

Bruna, Alejandra; Rueda, Oscar M; Greenwood, Wendy; Batra, Ankita Sati; Callari, Maurizio; Batra, Rajbir Nath; Pogrebniak, Katherine; Sandoval, Jose; Cassidy, John W; Tufegdzic-Vidakovic, Ana; Sammut, Stephen-John; Jones, Linda; Provenzano, Elena; Baird, Richard; Eirew, Peter; Hadfield, James; Eldridge, Matthew; McLaren-Douglas, Anne; Barthorpe, Andrew; Lightfoot, Howard; O'Connor, Mark J; Gray, Joe; Cortes, Javier; Baselga, Jose; Marangoni, Elisabetta; Welm, Alana L; Aparicio, Samuel; Serra, Violeta; Garnett, Mathew J; Caldas, Carlos.

Cell ; 167(1): 260-274.e22, 2016 09 22.

Artigo em Inglês | MEDLINE | ID: mdl-27641504

6.

Multi-omic machine learning predictor of breast cancer therapy response.

Sammut, Stephen-John; Crispin-Ortuzar, Mireia; Chin, Suet-Feung; Provenzano, Elena; Bardwell, Helen A; Ma, Wenxin; Cope, Wei; Dariush, Ali; Dawson, Sarah-Jane; Abraham, Jean E; Dunn, Janet; Hiller, Louise; Thomas, Jeremy; Cameron, David A; Bartlett, John M S; Hayward, Larry; Pharoah, Paul D; Markowetz, Florian; Rueda, Oscar M; Earl, Helena M; Caldas, Carlos.

Nature ; 601(7894): 623-629, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34875674

7.

Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups.

Rueda, Oscar M; Sammut, Stephen-John; Seoane, Jose A; Chin, Suet-Feung; Caswell-Jin, Jennifer L; Callari, Maurizio; Batra, Rajbir; Pereira, Bernard; Bruna, Alejandra; Ali, H Raza; Provenzano, Elena; Liu, Bin; Parisien, Michelle; Gillett, Cheryl; McKinney, Steven; Green, Andrew R; Murphy, Leigh; Purushotham, Arnie; Ellis, Ian O; Pharoah, Paul D; Rueda, Cristina; Aparicio, Samuel; Caldas, Carlos; Curtis, Christina.

Nature ; 567(7748): 399-404, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30867590

8.

Clustering of HR + /HER2- breast cancer in an Asian cohort is driven by immune phenotypes.

Pan, Jia-Wern; Ragu, Mohana; Chan, Wei-Qin; Hasan, Siti Norhidayu; Islam, Tania; Teoh, Li-Ying; Jamaris, Suniza; See, Mee-Hoong; Yip, Cheng-Har; Rajadurai, Pathmanathan; Looi, Lai-Meng; Taib, Nur Aishah Mohd; Rueda, Oscar M; Caldas, Carlos; Chin, Suet-Feung; Lim, Joanna; Teo, Soo-Hwang.

Breast Cancer Res ; 26(1): 67, 2024 Apr 22.

Artigo em Inglês | MEDLINE | ID: mdl-38649964

9.

Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype.

Madsen, Ralitsa R; Erickson, Emily C; Rueda, Oscar M; Robin, Xavier; Caldas, Carlos; Toker, Alex; Semple, Robert K; Vanhaesebroeck, Bart.

PLoS Genet ; 17(11): e1009876, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34762647

10.

Clinical interpretation of whole-genome and whole-transcriptome sequencing for precision oncology.

Jobanputra, Vaidehi; Wrzeszczynski, Kazimierz O; Buttner, Reinhard; Caldas, Carlos; Cuppen, Edwin; Grimmond, Sean; Haferlach, Torsten; Mullighan, Charles; Schuh, Anna; Elemento, Olivier.

Semin Cancer Biol ; 84: 23-31, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-34256129

11.

Clinical utility of whole-genome sequencing in precision oncology.

Rosenquist, Richard; Cuppen, Edwin; Buettner, Reinhard; Caldas, Carlos; Dreau, Helene; Elemento, Olivier; Frederix, Geert; Grimmond, Sean; Haferlach, Torsten; Jobanputra, Vaidehi; Meggendorfer, Manja; Mullighan, Charles G; Wordsworth, Sarah; Schuh, Anna.

Semin Cancer Biol ; 84: 32-39, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-34175442

12.

Analytical demands to use whole-genome sequencing in precision oncology.

Meggendorfer, Manja; Jobanputra, Vaidehi; Wrzeszczynski, Kazimierz O; Roepman, Paul; de Bruijn, Ewart; Cuppen, Edwin; Buttner, Reinhard; Caldas, Carlos; Grimmond, Sean; Mullighan, Charles G; Elemento, Olivier; Rosenquist, Richard; Schuh, Anna; Haferlach, Torsten.

Semin Cancer Biol ; 84: 16-22, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-34119643

13.

Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer.

São José, Celina; Garcia-Pelaez, José; Ferreira, Marta; Arrieta, Oscar; André, Ana; Martins, Nelson; Solís, Samantha; Martínez-Benítez, Braulio; Ordóñez-Sánchez, María Luisa; Rodríguez-Torres, Maribel; Sommer, Anna K; Te Paske, Iris B A W; Caldas, Carlos; Tischkowitz, Marc; Tusié, Maria Teresa; Hoogerbrugge, Nicoline; Demidov, German; de Voer, Richarda M; Laurie, Steve; Oliveira, Carla.

Gastric Cancer ; 26(5): 653-666, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37249750

14.

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo.

Ju, Young Seok; Martincorena, Inigo; Gerstung, Moritz; Petljak, Mia; Alexandrov, Ludmil B; Rahbari, Raheleh; Wedge, David C; Davies, Helen R; Ramakrishna, Manasa; Fullam, Anthony; Martin, Sancha; Alder, Christopher; Patel, Nikita; Gamble, Steve; O'Meara, Sarah; Giri, Dilip D; Sauer, Torril; Pinder, Sarah E; Purdie, Colin A; Borg, Åke; Stunnenberg, Henk; van de Vijver, Marc; Tan, Benita K T; Caldas, Carlos; Tutt, Andrew; Ueno, Naoto T; van 't Veer, Laura J; Martens, John W M; Sotiriou, Christos; Knappskog, Stian; Span, Paul N; Lakhani, Sunil R; Eyfjörd, Jórunn Erla; Børresen-Dale, Anne-Lise; Richardson, Andrea; Thompson, Alastair M; Viari, Alain; Hurles, Matthew E; Nik-Zainal, Serena; Campbell, Peter J; Stratton, Michael R.

Nature ; 543(7647): 714-718, 2017 03 30.

Artigo em Inglês | MEDLINE | ID: mdl-28329761

15.

Imaging breast cancer using hyperpolarized carbon-13 MRI.

Gallagher, Ferdia A; Woitek, Ramona; McLean, Mary A; Gill, Andrew B; Manzano Garcia, Raquel; Provenzano, Elena; Riemer, Frank; Kaggie, Joshua; Chhabra, Anita; Ursprung, Stephan; Grist, James T; Daniels, Charlie J; Zaccagna, Fulvio; Laurent, Marie-Christine; Locke, Matthew; Hilborne, Sarah; Frary, Amy; Torheim, Turid; Boursnell, Chris; Schiller, Amy; Patterson, Ilse; Slough, Rhys; Carmo, Bruno; Kane, Justine; Biggs, Heather; Harrison, Emma; Deen, Surrin S; Patterson, Andrew; Lanz, Titus; Kingsbury, Zoya; Ross, Mark; Basu, Bristi; Baird, Richard; Lomas, David J; Sala, Evis; Wason, James; Rueda, Oscar M; Chin, Suet-Feung; Wilkinson, Ian B; Graves, Martin J; Abraham, Jean E; Gilbert, Fiona J; Caldas, Carlos; Brindle, Kevin M.

Proc Natl Acad Sci U S A ; 117(4): 2092-2098, 2020 01 28.

Artigo em Inglês | MEDLINE | ID: mdl-31964840

16.

Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients.

Yau, Christina; Osdoit, Marie; van der Noordaa, Marieke; Shad, Sonal; Wei, Jane; de Croze, Diane; Hamy, Anne-Sophie; Laé, Marick; Reyal, Fabien; Sonke, Gabe S; Steenbruggen, Tessa G; van Seijen, Maartje; Wesseling, Jelle; Martín, Miguel; Del Monte-Millán, Maria; López-Tarruella, Sara; Boughey, Judy C; Goetz, Matthew P; Hoskin, Tanya; Gould, Rebekah; Valero, Vicente; Edge, Stephen B; Abraham, Jean E; Bartlett, John M S; Caldas, Carlos; Dunn, Janet; Earl, Helena; Hayward, Larry; Hiller, Louise; Provenzano, Elena; Sammut, Stephen-John; Thomas, Jeremy S; Cameron, David; Graham, Ashley; Hall, Peter; Mackintosh, Lorna; Fan, Fang; Godwin, Andrew K; Schwensen, Kelsey; Sharma, Priyanka; DeMichele, Angela M; Cole, Kimberly; Pusztai, Lajos; Kim, Mi-Ok; van 't Veer, Laura J; Esserman, Laura J; Symmans, W Fraser.

Lancet Oncol ; 23(1): 149-160, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34902335

17.

Androgen receptor function and targeted therapeutics across breast cancer subtypes.

Kolyvas, Emily A; Caldas, Carlos; Kelly, Kathleen; Ahmad, Saif S.

Breast Cancer Res ; 24(1): 79, 2022 11 14.

Artigo em Inglês | MEDLINE | ID: mdl-36376977

18.

Copy number heterogeneity identifies ER+ breast cancer patients that do not benefit from adjuvant endocrine therapy.

van den Bosch, Tom; Rueda, Oscar M; Caldas, Carlos; Vermeulen, Louis; Miedema, Daniël M.

Br J Cancer ; 127(7): 1332-1339, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-35864159

19.

Modeling the Prognostic Impact of Circulating Tumor Cells Enumeration in Metastatic Breast Cancer for Clinical Trial Design Simulation.

Gerratana, Lorenzo; Pierga, Jean-Yves; Reuben, James M; Davis, Andrew A; Wehbe, Firas H; Dirix, Luc; Fehm, Tanja; Nolé, Franco; Gisbert-Criado, Rafael; Mavroudis, Dimitrios; Grisanti, Salvatore; Garcia-Saenz, Jose A; Stebbing, Justin; Caldas, Carlos; Gazzaniga, Paola; Manso, Luis; Zamarchi, Rita; Bonotto, Marta; Fernandez de Lascoiti, Angela; De Mattos-Arruda, Leticia; Ignatiadis, Michail; Sandri, Maria-Teresa; Generali, Daniele; De Angelis, Carmine; Dawson, Sarah-Jane; Janni, Wolfgang; Carañana, Vicente; Riethdorf, Sabine; Solomayer, Erich-Franz; Puglisi, Fabio; Giuliano, Mario; Pantel, Klaus; Bidard, François-Clément; Cristofanilli, Massimo.

Oncologist ; 27(7): e561-e570, 2022 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-35278078

20.

The circular RNome of primary breast cancer.

Smid, Marcel; Wilting, Saskia M; Uhr, Katharina; Rodríguez-González, F Germán; de Weerd, Vanja; Prager-Van der Smissen, Wendy J C; van der Vlugt-Daane, Michelle; van Galen, Anne; Nik-Zainal, Serena; Butler, Adam; Martin, Sancha; Davies, Helen R; Staaf, Johan; van de Vijver, Marc J; Richardson, Andrea L; MacGrogan, Gaëten; Salgado, Roberto; van den Eynden, Gert G G M; Purdie, Colin A; Thompson, Alastair M; Caldas, Carlos; Span, Paul N; Sweep, Fred C G J; Simpson, Peter T; Lakhani, Sunil R; Van Laere, Steven; Desmedt, Christine; Paradiso, Angelo; Eyfjord, Jorunn; Broeks, Annegien; Vincent-Salomon, Anne; Futreal, Andrew P; Knappskog, Stian; King, Tari; Viari, Alain; Børresen-Dale, Anne-Lise; Stunnenberg, Hendrik G; Stratton, Mike; Foekens, John A; Sieuwerts, Anieta M; Martens, John W M.

Genome Res ; 29(3): 356-366, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30692147

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