Detalhe da pesquisa
1.
Repeatability of MRI Biomarkers in Nonalcoholic Fatty Liver Disease: The NIMBLE Consortium.
Radiology
; 309(1): e231092, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37815451
2.
The effects of ertugliflozin on ß-cell function: Pooled analysis from four phase 3 randomized controlled studies.
Diabetes Obes Metab
; 22(12): 2267-2275, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32700393
3.
Decreased VMAT2 in the pancreas of humans with type 2 diabetes mellitus measured in vivo by PET imaging.
Diabetologia
; 61(12): 2598-2607, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29721633
4.
Efficacy and safety of the glucagon receptor antagonist PF-06291874: A 12-week, randomized, dose-response study in patients with type 2 diabetes mellitus on background metformin therapy.
Diabetes Obes Metab
; 20(11): 2608-2616, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29923286
5.
Once-weekly administration of a long-acting fibroblast growth factor 21 analogue modulates lipids, bone turnover markers, blood pressure and body weight differently in obese people with hypertriglyceridaemia and in non-human primates.
Diabetes Obes Metab
; 19(12): 1762-1772, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28573777
6.
Mechanistic investigation of the preclinical pharmacokinetics and interspecies scaling of PF-05231023, a fibroblast growth factor 21-antibody protein conjugate.
Drug Metab Dispos
; 43(6): 803-11, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25805881
7.
Pharmacokinetics and pharmacodynamics of PF-05231023, a novel long-acting FGF21 mimetic, in a first-in-human study.
Br J Clin Pharmacol
; 80(5): 1051-63, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25940675
8.
Arginine is preferred to glucagon for stimulation testing of ß-cell function.
Am J Physiol Endocrinol Metab
; 307(8): E720-7, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25159323
9.
Investigation of pharmacokinetic drug interaction between clesacostat and DGAT2 inhibitor ervogastat in healthy adult participants.
Clin Transl Sci
; 17(2): e13687, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38362827
10.
The relationship between weight gain during chemotherapy and outcomes in patients with advanced non-small cell lung cancer.
J Cachexia Sarcopenia Muscle
; 15(3): 1030-1040, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38468440
11.
A Phase Ib First-In-Patient Study Assessing the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ponsegromab in Participants with Cancer and Cachexia.
Clin Cancer Res
; 30(3): 489-497, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37982848
12.
Clinical and scientific value in the pursuit of quantification of beta cells in the pancreas by PET imaging.
Diabetologia
; 61(12): 2671-2673, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30136144
13.
Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans.
Am J Physiol Gastrointest Liver Physiol
; 304(11): G958-69, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23558010
14.
Diagnostic performance of circulating biomarkers for non-alcoholic steatohepatitis.
Nat Med
; 29(10): 2656-2664, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679433
15.
Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).
J Lipid Res
; 53(5): 1000-1011, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22368281
16.
The prevalence of low muscle mass associated with obesity in the USA.
Skelet Muscle
; 12(1): 26, 2022 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36539856
17.
Inhibition of ketohexokinase in adults with NAFLD reduces liver fat and inflammatory markers: A randomized phase 2 trial.
Med
; 2(7): 800-813.e3, 2021 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35590219
18.
ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a trials.
Nat Med
; 27(10): 1836-1848, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635855
19.
Effects of Ertugliflozin on Liver Enzymes in Patients with Type 2 Diabetes: A Post-Hoc Pooled Analysis of Phase 3 Trials.
Diabetes Ther
; 11(8): 1849-1860, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32648108
20.
GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates.
Cell Metab
; 32(6): 938-950.e6, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33207247