Detalhe da pesquisa
1.
Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence.
EMBO Rep
; 23(2): e54384, 2022 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34914165
2.
Author Correction: Rapid and efficient induction of functional astrocytes from human pluripotent stem cells.
Nat Methods
; 16(1): 134, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514884
3.
Rapid and efficient induction of functional astrocytes from human pluripotent stem cells.
Nat Methods
; 15(9): 693-696, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30127505
4.
Sanfilippo Syndrome: Molecular Basis, Disease Models and Therapeutic Approaches.
Int J Mol Sci
; 21(21)2020 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33105639
5.
Mitochondrial Dysfunction and Calcium Dysregulation in Leigh Syndrome Induced Pluripotent Stem Cell Derived Neurons.
Int J Mol Sci
; 21(9)2020 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32366037
6.
Transcription Factor-Forced Astrocytic Differentiation Impairs Human Glioblastoma Growth In Vitro and In Vivo.
Mol Cancer Ther
; 22(2): 274-286, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36508391
7.
Astrocyte dysfunction and neuronal network hyperactivity in a CRISPR engineered pluripotent stem cell model of frontotemporal dementia.
Brain Commun
; 5(3): fcad158, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37274831
8.
Genome Editing Using Cas9-gRNA Ribonucleoprotein in Human Pluripotent Stem Cells for Disease Modeling.
Methods Mol Biol
; 2549: 409-425, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-33755903
9.
FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis.
Front Cell Dev Biol
; 10: 1039636, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36313554
10.
Transcription factor-based direct conversion of human fibroblasts to functional astrocytes.
Stem Cell Reports
; 17(7): 1620-1635, 2022 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35750047
11.
CRISPR/Cas9 Genome Engineering in Human Pluripotent Stem Cells for Modeling of Neurological Disorders.
Methods Mol Biol
; 2352: 237-251, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34324191
12.
Transcription Factor-Based Strategies to Generate Neural Cell Types from Human Pluripotent Stem Cells.
Cell Reprogram
; 23(4): 206-220, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34388027
13.
Transcription Factor Programming of Human Pluripotent Stem Cells to Functionally Mature Astrocytes for Monocultures and Cocultures with Neurons.
Methods Mol Biol
; 2352: 133-148, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34324185
14.
NGN2 mmRNA-Based Transcriptional Programming in Microfluidic Guides hiPSCs Toward Neural Fate With Multiple Identities.
Front Cell Neurosci
; 15: 602888, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33679325
15.
Neuronal and Astrocytic Differentiation from Sanfilippo C Syndrome iPSCs for Disease Modeling and Drug Development.
J Clin Med
; 9(3)2020 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32121121
16.
In Vitro Functional Characterization of Human Neurons and Astrocytes Using Calcium Imaging and Electrophysiology.
Methods Mol Biol
; 1919: 73-88, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30656622
17.
EXTL2 and EXTL3 inhibition with siRNAs as a promising substrate reduction therapy for Sanfilippo C syndrome.
Sci Rep
; 5: 13654, 2015 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26347037
18.
Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome.
Stem Cell Res
; 42: 101668, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31825816
19.
Activity and High-Order Effective Connectivity Alterations in Sanfilippo C Patient-Specific Neuronal Networks.
Stem Cell Reports
; 5(4): 546-57, 2015 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26411903
20.
Generation of two compound heterozygous HGSNAT-mutated lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo C syndrome.
Stem Cell Res
; 41: 101616, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31731183