Detalhe da pesquisa
1.
The Life Cycle of the Mu-Opioid Receptor.
Trends Biochem Sci
; 46(4): 315-328, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33127216
2.
Opioid-Induced Pronociceptive Signaling in the Gastrointestinal Tract Is Mediated by Delta-Opioid Receptor Signaling.
J Neurosci
; 42(16): 3316-3328, 2022 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35256532
3.
Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain.
Proc Natl Acad Sci U S A
; 117(26): 15281-15292, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32546520
4.
A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes.
J Biol Chem
; 296: 100345, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33515548
5.
Positive allosteric modulation of endogenous delta opioid receptor signaling in the enteric nervous system is a potential treatment for gastrointestinal motility disorders.
Am J Physiol Gastrointest Liver Physiol
; 322(1): G66-G78, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34755545
6.
A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor.
Proc Natl Acad Sci U S A
; 116(44): 22353-22358, 2019 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611414
7.
Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer.
Proc Natl Acad Sci U S A
; 116(9): 3863-3872, 2019 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30733293
8.
Phosphoproteomic characterization of the signaling network resulting from activation of the chemokine receptor CCR2.
J Biol Chem
; 295(19): 6518-6531, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32241914
9.
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome.
Proc Natl Acad Sci U S A
; 115(31): E7438-E7447, 2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012612
10.
Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10.
Int J Mol Sci
; 22(8)2021 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33921794
11.
Opioid Pharmacology under the Microscope.
Mol Pharmacol
; 98(4): 425-432, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32198210
12.
Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1.
J Biol Chem
; 294(10): 3464-3475, 2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30567735
13.
Ligand-dependent spatiotemporal signaling profiles of the µ-opioid receptor are controlled by distinct protein-interaction networks.
J Biol Chem
; 294(44): 16198-16213, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515267
14.
G-Protein-Coupled Receptors Are Dynamic Regulators of Digestion and Targets for Digestive Diseases.
Gastroenterology
; 156(6): 1600-1616, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30771352
15.
Agonist-dependent development of delta opioid receptor tolerance in the colon.
Cell Mol Life Sci
; 76(15): 3033-3050, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-30904952
16.
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission.
Proc Natl Acad Sci U S A
; 114(46): 12309-12314, 2017 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29087309
17.
Clathrin and GRK2/3 inhibitors block δ-opioid receptor internalization in myenteric neurons and inhibit neuromuscular transmission in the mouse colon.
Am J Physiol Gastrointest Liver Physiol
; 317(2): G79-G89, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31091149
18.
Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs.
Nature
; 503(7475): 295-9, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24121438
19.
Influence of Chemokine N-Terminal Modification on Biased Agonism at the Chemokine Receptor CCR1.
Int J Mol Sci
; 20(10)2019 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31096719
20.
Proteomic Identification of Interferon-Induced Proteins with Tetratricopeptide Repeats as Markers of M1 Macrophage Polarization.
J Proteome Res
; 17(4): 1485-1499, 2018 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29508616