Detalhe da pesquisa
1.
Structural basis of specific inhibition of extracellular activation of pro- or latent myostatin by the monoclonal antibody SRK-015.
J Biol Chem
; 295(16): 5404-5418, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32075906
2.
Characterization of binding mode of action of a blocking anti-platelet-derived growth factor (PDGF)-B monoclonal antibody, MOR8457, reveals conformational flexibility and avidity needed for PDGF-BB to bind PDGF receptor-ß.
Biochemistry
; 54(10): 1918-29, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25707433
3.
Risk-Based Control Strategies of Recombinant Monoclonal Antibody Charge Variants.
Antibodies (Basel)
; 11(4)2022 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36412839
4.
A Sensitive and Selective Immunoassay for the Quantitation of Serum Latent Myostatin after In Vivo Administration of SRK-015, a Selective Inhibitor of Myostatin Activation.
SLAS Discov
; 25(1): 95-103, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31347449
5.
Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design.
PLoS One
; 15(5): e0232713, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32379792
6.
Selective inhibition of TGFß1 activation overcomes primary resistance to checkpoint blockade therapy by altering tumor immune landscape.
Sci Transl Med
; 12(536)2020 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32213632
7.
Biophysical and Immunological Characterization and In Vivo Pharmacokinetics and Toxicology in Nonhuman Primates of the Anti-PD-1 Antibody Pembrolizumab.
Mol Cancer Ther
; 19(6): 1298-1307, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32229606
8.
PD-1 blockade augments Th1 and Th17 and suppresses Th2 responses in peripheral blood from patients with prostate and advanced melanoma cancer.
J Immunother
; 35(2): 169-78, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22306905
9.
Probing the ligand-induced conformational change in HLA-DR1 by selective chemical modification and mass spectrometric mapping.
Biochemistry
; 44(42): 13625-37, 2005 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-16229453
10.
Induced fit of an epitope peptide to a monoclonal antibody probed with a novel parallel surface plasmon resonance assay.
J Biol Chem
; 280(6): 4188-94, 2005 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-15556932
11.
Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism.
J Immunol
; 175(4): 2237-43, 2005 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16081791
12.
Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding.
J Biol Chem
; 279(16): 16561-70, 2004 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-14757758