Different learning aberrations relate to delusion-like beliefs with different contents.

The prediction error account of delusions has had success. However, its explanation of delusions with different contents has been lacking. Persecutory delusions and paranoia are the common unfounded beliefs that others have harmful intentions towards us. Other delusions include believing that one's thoughts or actions are under external control, or that events in the world have specific personal meaning. We compare learning on two different cognitive tasks, probabilistic reversal learning (PRL) and Kamin blocking, that have relationships to paranoid and non-paranoid delusion-like beliefs, respectively. We find that Clinical High-Risk status alone does not result in different behavioral results on the PRL task but that an individual's level of paranoia is associated with excessive switching behavior. During the Kamin blocking task, paranoid individuals learned inappropriately about the blocked cue. However, they also had decreased learning about the control cue, suggesting more general learning impairments. Non-paranoid delusion-like belief conviction (but not paranoia) was associated with aberrant learning about the blocked cue but intact learning about the control cue, suggesting specific impairments in learning related to cue combination. We fit task-specific computational models separately to behavioral data to explore how latent parameters vary within individuals between tasks, and how they can explain symptom-specific effects. We find that paranoia is associated with low learning rates on the PRL task as well as the blocking task. Non-paranoid delusion-like belief conviction was instead related to parameters controlling the degree and direction of similarity between cue updating during simultaneous cue presentation. These results suggest that paranoia and other delusion-like beliefs involve dissociable deficits in learning and belief updating, which - given the transdiagnostic status of paranoia - may have differential utility in predicting psychosis.

The retrosplenial cortex as a possible "sensory integration" area: A neural network modeling approach of the differential outcomes effect in negative patterning.

We explored the hypothesis that learning a Pavlovian negative patterning task would be facilitated when training with differential, as opposed to non-differential, reinforcing outcomes. Two groups of rats received pairings of one visual and one auditory stimulus with food reward when these stimuli were presented on separate training trials, but without reward when both stimuli were presented on simultaneous stimulus compound trials (V+, A+, AV-; similar to an XOR problem). For Group Differential, each stimulus was separately paired with distinctively tasting food rewards, whereas for Group Non-Differential each stimulus was randomly paired with both food reward types across different stimulus element trials. We observed that rats learned the negative patterning task more rapidly and effectively when trained with differential outcomes. These data support a multi-layered connectionist model introduced by Delamater (2012) in which a multi-modal processing structure plays the role of a "sensory integration" area like that hypothesized for the retrosplenial cortex by Dave Bucci and his colleagues (e.g., Todd, Fournier, & Bucci, 2019). We discuss how such a region may develop different "negative occasion setting" and "configural inhibition" mechanisms in solving negative patterning and related tasks.

Excessive teleological thinking is driven by aberrant associations and not by failure of reasoning.

Teleological thought - the tendency to ascribe purpose to objects and events - is useful in some cases (encouraging explanation-seeking), but harmful in others (fueling delusions and conspiracy theories). What drives excessive and maladaptive teleological thinking? In causal learning, there is a fundamental distinction between associative learning versus learning via propositional mechanisms. Here, we propose that directly contrasting the contributions of these two pathways can elucidate the roots of excess teleology. We modified a causal learning task such that we could encourage associative versus propositional mechanisms in different instances. Across three experiments (total N = 600), teleological tendencies were correlated with delusion-like ideas and uniquely explained by aberrant associative learning, but not by learning via propositional rules. Computational modeling suggested that the relationship between associative learning and teleological thinking can be explained by excessive prediction errors that imbue random events with more significance - providing a new understanding for how humans make meaning of lived events.

Determinants of extinction in a streamed trial procedure.

The strength of an association between a cue and its outcome is influenced by both the probability of the outcome given the cue and the probability of the outcome in the absence of the cue. Once an association has been formed, extinction is the procedure for reducing responding indicative of the association by repeated presentation of the cue without the outcome. The present experiments tested whether cumulative frequency and/or cumulative duration of these events affects associative extinction in a streamed trial extinction procedure with human participants. Experiment 1 assessed the effects of parametric manipulations of the frequency and duration of either the cue by itself or cue-outcome co-absence. In Experiment 1, participants proved relatively insensitive to manipulation of the event's duration. In contrast, judgements of the association by participants decreased when the frequency of cue-alone events was increased, even when the durations of those events were decreased so that cumulative exposure to the cue was equated. No effect of either the duration or the frequency of cue-outcome co-absence was observed. Experiment 2 demonstrated that the effect of cue-alone (i.e., extinction trial) frequency generalises across a wide range of parameters for initial acquisition achieved by cue-outcome pairings. Experiment 3 tested for an interaction between event duration during initial learning and event duration during extinction. Collectively, these results indicate that the cumulative frequency, and not the cumulative duration, of extinction trials as well as the duration of the cue-outcome co-absences between extinction trials control the effectiveness of an extinction procedure.

Two-stage reinforcement learning task predicts psychological traits.

External sources of information influence human actions. However, psychological traits (PTs), considered internal variables, also play a crucial role in decision making. PTs are stable across time and contexts and define the set of behavioral repertoires that individuals express. Here, we explored how multiple metrics of adaptive behavior under uncertainty related to several PTs. Participants solved a reversal-learning task with volatile contingencies, from which we characterized a detailed behavioral profile based on their response sequences. We then tested the relationship between this multimetric behavioral profile and scores obtained from self-report psychological questionnaires. The PT measurements were based on the Hierarchical Taxonomy Of Psychopathology (HiTOP) model. By using multiple linear regression models (MLRMs), we found that the learning curves predicted important differences in the PTs and task response times. We confirmed the significance of these relationships by using random permutations of the predictors of the MLRM. Therefore, the behavioral profile configurations predicted the PTs and served as a "fingerprint" to identify participants with a high certainty level. We discuss briefly how this characterization and approach could contribute to better nosological classifications.

More frequent, shorter trials enhance acquisition in a training session: There is a free lunch!

The strength of the learned relation between two events, a model for causal perception, has been found to depend on their overall statistical relation, and might be expected to be related to both training trial frequency and trial duration. We report five experiments using a rapid-trial streaming procedure containing Event 1-Event 2 pairings (A trials), Event 1-alone (B trials), Event 2-alone (C trials), and neither event (D trials), in which trial frequencies and durations were independently varied. Judgements of association increased with increasing frequencies of A trials and decreased with increasing frequencies of both B and C trials but showed little effect of frequency of D trials. Across five experiments, a weak but often significant effect of trial duration was also detected, which was always in the same direction as trial frequency. Thus, both frequency and duration of trials influenced learning, but frequency had decidedly stronger effects. Importantly, the benefit of more trials greatly outweighed the observed reduction in effect size caused by a proportional decrease in trial duration. In experiment 5, more trials of proportionately shorter duration enhanced effects on contingency judgments despite a shortening of the training session. We consider the observed 'frequency advantage' with respect to both frequentist models of learning and models based on information. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Benefiting from trial spacing without the cost of prolonged training: Frequency, not duration, of trials with absent stimuli enhances perceived contingency.

The statistical relation between two events influences the perception of how one event relates to the presence or absence of another. Interestingly, the simultaneous absence of both events, just like their mutual occurrence, is relevant for describing their contingency. In three experiments, we explored the relevance of coabsent events by varying the duration and frequency of trials without stimuli. We used a rapid trial streaming procedure and found that the perceived association between events is enhanced with increasing frequency of coabsent events, unlike the duration of coabsent events, which had little effect. These findings suggest ways in which the benefits of trial spacing, during which both events are absent, could be obtained without increasing total training time. Centrally, this can be done by frequent repeating of shortened coabsent events, each marked by a trial contextual cue. We discuss four potential accounts of how coabsent experience might be processed contributing to this effect: (a) contingency sensitivity, (b) testing effect, (c) reduced associative interference by the context, and (d) reduced encoding interference. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Alexithymia explains atypical spatiotemporal dynamics of eye gaze in autism.

Recognition of emotional facial expressions is considered to be atypical in autism. This difficulty is thought to be due to the way that facial expressions are visually explored. Evidence for atypical visual exploration of emotional faces in autism is, however, equivocal. We propose that, where observed, atypical visual exploration of emotional facial expressions is due to alexithymia, a distinct but frequently co-occurring condition. In this eye-tracking study we tested the alexithymia hypothesis using a number of recent methodological advances to study eye gaze during several emotion processing tasks (emotion recognition, intensity judgements, free gaze), in 25 adults with, and 45 without, autism. A multilevel polynomial modelling strategy was used to describe the spatiotemporal dynamics of eye gaze to emotional facial expressions. Converging evidence from traditional and novel analysis methods revealed that atypical gaze to the eyes is best predicted by alexithymia in both autistic and non-autistic individuals. Information theoretic analyses also revealed differential effects of task on gaze patterns as a function of alexithymia, but not autism. These findings highlight factors underlying atypical emotion processing in autistic individuals, with wide-ranging implications for emotion research.

Isomorphic decisional biases across perceptual tasks.

Humans adjust their behavioral strategies to maximize rewards. However, in the laboratory, human decisional biases exist and persist in two alternative tasks, even when this behavior leads to a loss in utilities. Such biases constitute the tendency to choose one action over others and emerge from a combination of external and internal factors that are specific for each individual. Here, we explored the idea that internally-mediated decisional biases should stably occur and, hence, be reflected across multiple behavioral tasks. Our experimental results confirm this notion and illustrate how participants exhibited similar choice biases across days and tasks. Moreover, we show how side-choice behavior in a two alternative choice task served to identify participants, suggesting that individual traits could underlie these choice biases. The tasks and analytic tools developed for this study should become instrumental in exploring the interaction between internal and external factors that contribute to decisional biases. They could also serve to detect psychopathologies that involve aberrant levels of choice variability.