RESUMO
The objective of this research was to examine the Love-Hate and Identification Relationship of Individuals Participating in Euroleague Match for Recreational Purposes. The study was conducted using a relational survey methodology. The study's population comprises persons who watching recreational purpose part in the Euroleague match held in Istanbul in 2023-2024 season, while the sample consists of 178 voluntary participants selected through convenience sampling. The participants completed the Fan Love-Hate Scale and Fan Identification Scale, in addition to being asked about their gender, marital status, age, educational status, and frequency of attending football matches per week. The data collected from the personal information form and scales was entered into the IBM SPSS 24.0 software package for analysis. Statistical analyses were conducted using the Independent Sample T test and One-way Anova methods. The LSD test was employed to ascertain the dissimilarity between the groups. The Pearson correlation analysis was utilized to ascertain the association between the variables of love-hate and identity. In summary, it is evident that demographic factors, including gender and age, significantly influence fan perceptions and sports identification. In contrast, there is no substantial correlation observed between attributes such as level of education achieved and the frequency of engaging in sports activities, and the aforementioned outcomes. The significant associations identified between the Fan Love-Hate Scale and the Sports Fan Identification Scale underscore the complex relationship between fans' emotional experiences and their connection to sports. Further investigations could be conducted to go deeper into the underlying causes that contribute to these relationships and inequalities, so resulting in a more thorough understanding of fan psychology.
Assuntos
Basquetebol , Humanos , Masculino , Feminino , Adulto , Basquetebol/psicologia , Adulto Jovem , Recreação , Amor , Inquéritos e Questionários , Adolescente , Pessoa de Meia-IdadeRESUMO
Objectives: Triazolopyrimidinones are compounds used in medicinal chemistry. In this study, three novel triazolopyrimidinone derivatives were synthesized as drug candidates: (5-(chloromethyl)-2-(4-methoxyphenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one) (S1-TP), 2-(4-methoxyphenyl)-5-(piperidinomethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one) (S2-TP), and 2-(4-methoxyphenyl)-5-(morpholinomethyl)-[1,2,4]triazolo[1,5-a] pyrimidin-7(3H)-one) (S3-TP). Their electrochemical properties were investigated for the first time using voltammetric techniques on carbon graphite electrodes. Moreover, stability tests for each drug candidate were performed on different days. After revealing the electrochemical properties of the drug candidates, their effect on double-stranded (ds) DNA was examined by measuring the oxidation currents of the guanine of dsDNA before and after the interaction. Materials and Methods: An electrochemical setup that included a pencil graphite electrode as the working electrode, an Ag/AgCl reference electrode, and a platinum wire as the auxiliary electrode was used in this study. Experiments for optimum pH, scan rate, and concentration of drug candidates were conducted. The interaction between Ss-TP and dsDNA was evaluated using differential pulse voltammetry. The stability of each drug candidate was tested on various days. Results: A comprehensive characterization of the S1-TP, S2-TP, and S3-TP compounds was performed for the first time. This study showed that the electrochemical oxidation of S1-TP and S2-TP was irreversible and diffusion-controlled. In addition, the transfer of electrons in S3-TP was controlled by adsorption. The interaction between Ss-TP and dsDNA resulted in notable changes in the peak potentialof dsDNA. The dsDNA peak potential shifted negatively after interaction with S1-TP, S2-TP, and S3-TP. Under optimum conditions, the detection limits for S1-TP, S2-TP, and S3-TP were 1.5 µg/mL, 1.0 µg/mL, and 2.0 µg/mL, respectively. Conclusion: From our experimental data, we concluded that these molecules can be used as drug molecules because of their remarkable effects on DNA.