Detalhe da pesquisa
1.
Myeloid-specific fatty acid transport protein 4 deficiency induces a sex-dimorphic susceptibility for nonalcoholic steatohepatitis in mice fed a high-fat, high-cholesterol diet.
Am J Physiol Gastrointest Liver Physiol
; 324(5): G389-G403, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36881564
2.
FATP4 deletion in liver cells induces elevation of extracellular lipids via metabolic channeling towards triglycerides and lipolysis.
Biochem Biophys Res Commun
; 687: 149161, 2023 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37931418
3.
Skin permeability barrier formation by the ichthyosis-causative gene FATP4 through formation of the barrier lipid ω-O-acylceramide.
Proc Natl Acad Sci U S A
; 117(6): 2914-2922, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31974308
4.
FATP4 inactivation in cultured macrophages attenuates M1- and ER stress-induced cytokine release via a metabolic shift towards triacylglycerides.
Biochem J
; 478(10): 1861-1877, 2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33900381
5.
iPLA2ß-Null Mice Show HCC Protection by an Induction of Cell-Cycle Arrest after Diethylnitrosamine Treatment.
Int J Mol Sci
; 23(22)2022 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430237
6.
Plasma Lipidome, PNPLA3 polymorphism and hepatic steatosis in hereditary hemochromatosis.
BMC Gastroenterol
; 20(1): 230, 2020 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32680469
7.
Elevation of blood lipids in hepatocyte-specific fatty acid transport 4-deficient mice fed with high glucose diets.
Mol Genet Metab
; 126(1): 30-38, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30497809
8.
Bivalent Ligand UDCA-LPE Inhibits Pro-Fibrogenic Integrin Signalling by Inducing Lipid Raft-Mediated Internalization.
Int J Mol Sci
; 19(10)2018 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30347788
9.
iPLA2ß deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling.
Biochim Biophys Acta
; 1861(5): 449-61, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26873633
10.
Ageing sensitized by iPLA2ß deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(12): 1520-1533, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28888832
11.
Palmitate activation by fatty acid transport protein 4 as a model system for hepatocellular apoptosis and steatosis.
Biochim Biophys Acta
; 1851(5): 549-65, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25603556
12.
Sensitization to autoimmune hepatitis in group VIA calcium-independent phospholipase A2-null mice led to duodenal villous atrophy with apoptosis, goblet cell hyperplasia and leaked bile acids.
Biochim Biophys Acta
; 1852(8): 1646-57, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25957555
13.
Ursodeoxycholyl Lysophosphatidylethanolamide modifies aberrant lipid profiles in NAFLD.
Eur J Clin Invest
; 45(9): 925-31, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26108973
14.
Plasma membrane phospholipase A2 controls hepatocellular fatty acid uptake and is responsive to pharmacological modulation: implications for nonalcoholic steatohepatitis.
FASEB J
; 28(7): 3159-70, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24719358
15.
Deficiency of Group VIA Phospholipase A2 (iPLA2ß) Renders Susceptibility for Chemical-Induced Colitis.
Dig Dis Sci
; 60(12): 3590-602, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26182903
16.
Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1α activation.
Biochim Biophys Acta Mol Basis Dis
; 1870(3): 167016, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38198970
17.
Ursodeoxycholyl lysophosphatidylethanolamide inhibits lipoapoptosis by shifting fatty acid pools toward monosaturated and polyunsaturated fatty acids in mouse hepatocytes.
Mol Pharmacol
; 84(5): 696-709, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23974795
18.
Ursodeoxycholyl lysophosphatidylethanolamide improves steatosis and inflammation in murine models of nonalcoholic fatty liver disease.
Hepatology
; 55(5): 1369-78, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22183915
19.
Myeloid- and hepatocyte-specific deletion of group VIA calcium-independent phospholipase A2 leads to dichotomous opposing phenotypes during MCD diet-induced NASH.
Biochim Biophys Acta Mol Basis Dis
; 1869(1): 166590, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36334837
20.
Adipocyte-specific inactivation of Acyl-CoA synthetase fatty acid transport protein 4 (Fatp4) in mice causes adipose hypertrophy and alterations in metabolism of complex lipids under high fat diet.
J Biol Chem
; 286(41): 35578-35587, 2011 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21808061