Pesquisa | BVS Violência e Saúde

1.

Actinin-4 controls survival signaling in B cells by limiting the lateral mobility of B-cell antigen receptors.

Alsouri, Saed; Ambrose, Ashley; Mougios, Nikolaos; Paglilla, Nadia; Mayr, Florian; Choi, Kate; Loeber, Jens; Chapuy, Björn; Haeupl, Björn; Opazo, Felipe; Oellerich, Thomas; Gold, Michael; Engelke, Michael.

Eur J Immunol ; 54(3): e2350774, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38299456

2.

MYD88L265P augments proximal B-cell receptor signaling in large B-cell lymphomas via an interaction with DOCK8.

Mandato, Elisa; Yan, Qingsheng; Ouyang, Jing; Paczkowska, Julia; Qin, Yan; Hao, Yansheng; Bojarczuk, Kamil; Hansen, Julia; Chapuy, Björn; Rodig, Scott J; Khan, Sumbul Jawed; Redd, Robert A; Shipp, Margaret A.

Blood ; 142(14): 1219-1232, 2023 10 05.

Artigo em Inglês | MEDLINE | ID: mdl-37467575

3.

Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53-deficient B-cell malignancies.

Izquierdo, Elena; Vorholt, Daniela; Blakemore, Stuart; Sackey, Benedict; Nolte, Janica L; Barbarino, Verena; Schmitz, Jan; Nickel, Nadine; Bachurski, Daniel; Lobastova, Liudmila; Nikolic, Milos; Michalik, Michael; Brinker, Reinhild; Merkel, Olaf; Franitza, Marek; Georgomanolis, Theodoros; Neuhaus, René; Koch, Maximilian; Nasada, Niklas; Knittel, Gero; Chapuy, Björn; Ludwig, Nicole; Meese, Eckart; Frenzel, Lukas; Reinhardt, Hans Christian; Peifer, Martin; Rebollido-Rios, Rocio; Bruns, Heiko; Krüger, Marcus; Hallek, Michael; Pallasch, Christian P.

Blood ; 139(25): 3617-3629, 2022 06 23.

Artigo em Inglês | MEDLINE | ID: mdl-35344582

4.

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.

Wilke, Anne C; Doebele, Carmen; Zindel, Alena; Lee, Kwang Seok; Rieke, Sara A; Ceribelli, Michele; Comoglio, Federico; Phelan, James D; Wang, James Q; Pikman, Yana; Jahn, Dominique; Häupl, Björn; Schneider, Constanze; Scheich, Sebastian; Tosto, Frances A; Bohnenberger, Hanibal; Stauder, Philipp; Schnütgen, Frank; Slabicki, Mikolaj; Coulibaly, Zana A; Wolf, Sebastian; Bojarczuk, Kamil; Chapuy, Björn; Brandts, Christian H; Stroebel, Philipp; Lewis, Caroline A; Engelke, Michael; Xu, Xincheng; Kim, Hahn; Dang, Thanh Hung; Schmitz, Roland; Hodson, Daniel J; Stegmaier, Kimberly; Urlaub, Henning; Serve, Hubert; Schmitt, Clemens A; Kreuz, Fernando; Knittel, Gero; Rabinowitz, Joshua D; Reinhardt, Hans Christian; Vander Heiden, Matthew G; Thomas, Craig; Staudt, Louis M; Zenz, Thorsten; Oellerich, Thomas.

Blood ; 139(4): 538-553, 2022 01 27.

Artigo em Inglês | MEDLINE | ID: mdl-34624079

5.

Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma.

Fangazio, Marco; Ladewig, Erik; Gomez, Karen; Garcia-Ibanez, Laura; Kumar, Rahul; Teruya-Feldstein, Julie; Rossi, Davide; Filip, Ioan; Pan-Hammarström, Qiang; Inghirami, Giorgio; Boldorini, Renzo; Ott, German; Staiger, Annette M; Chapuy, Björn; Gaidano, Gianluca; Bhagat, Govind; Basso, Katia; Rabadan, Raul; Pasqualucci, Laura; Dalla-Favera, Riccardo.

Proc Natl Acad Sci U S A ; 118(22)2021 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-34050029

6.

SH2 domain-containing inositol 5-phosphatases support the survival of Burkitt lymphoma cells by promoting energy metabolism.

Mayr, Florian; Kruse, Vanessa; Fuhrmann, Dominik C; Wolf, Sebastian; Löber, Jens; Alsouri, Saed; Paglilla, Nadia; Lee, Kwang; Chapuy, Björn; Brüne, Bernhard; Zenz, Thorsten; Häupl, Björn; Oellerich, Thomas; Engelke, Michael.

Haematologica ; 2023 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-37916396

7.

Molecular classification of aggressive lymphomas-past, present, future.

Wienand, Kirsty; Chapuy, Björn.

Hematol Oncol ; 39 Suppl 1: 24-30, 2021 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-34105819

8.

Disseminated itching papules in a Jamaican patient.

Klemp, Marisa; Chapuy, Björn; von Brünneck, Ann-Christin; Dobos, Gabor; Moritz, Rose K C.

J Dtsch Dermatol Ges ; 22(1): 123-125, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-37847912

9.

Clonal hematopoiesis with TET2 mutations spawning synchronous primary central nervous system lymphoma and myelodysplastic syndrome.

Treiber, Hannes; Ganster, Christina; Schanz, Julie; Shimono, Joji; Zechel, Sabrina; Pohanyar, Nilofar; Riedel, Christian; Stadelmann, Christine; Haase, Detlef; Trümper, Lorenz; Chapuy, Björn; Wulf, Gerald G.

Ann Hematol ; 102(12): 3631-3633, 2023 12.

Artigo em Inglês | MEDLINE | ID: mdl-37702823

10.

Modified BEAM with triple autologous stem cell transplantation for patients with relapsed aggressive non-Hodgkin lymphoma.

Hohloch, Karin; Zeynalova, Samira; Chapuy, Björn; Pfreundschuh, Michael; Loeffler, Markus; Ziepert, Marita; Feller, Alfred C; Trümper, Lorenz; Hasenclever, Dirk; Wulf, Gerald; Schmitz, Norbert.

Ann Hematol ; 95(7): 1121-8, 2016 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-27165090

11.

Tropism of PCNSL: is it all about autoantigens?

Chapuy, Björn.

Blood ; 132(26): 2704-2706, 2018 12 27.

Artigo em Inglês | MEDLINE | ID: mdl-30591542

12.

[Malignant lymphomas - quo vadis? - What developments await us in diagnostics and therapy?] / Maligne Lymphome Quo vadis?

Alig, Stefan; Pott, Christiane; Chapuy, Björn.

Dtsch Med Wochenschr ; 149(11): 638-645, 2024 May.

Artigo em Alemão | MEDLINE | ID: mdl-38749440

13.

An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL.

Prinz, Lars Fabian; Riet, Tobias; Neureuther, Daniel Felix; Lennartz, Simon; Chrobok, Danuta; Hübbe, Hanna; Uhl, Gregor; Riet, Nicole; Hofmann, Petra; Hösel, Marianna; Simon, Adrian Georg; Tetenborg, Luis; Segbers, Paul; Shimono, Joji; Gödel, Philipp; Balke-Want, Hyatt; Flümann, Ruth; Knittel, Gero; Reinhardt, Hans Christian; Scheid, Christoph; Büttner, Reinhard; Chapuy, Björn; Ullrich, Roland Tillmann; Hallek, Michael; Chmielewski, Markus Martin.

Cell Rep Med ; 5(2): 101421, 2024 Feb 20.

Artigo em Inglês | MEDLINE | ID: mdl-38340727

14.

A prospective observational study of real-world treatment and outcome in secondary CNS lymphoma.

Habringer, Stefan; Demel, Uta M; Fietz, Anne-Katrin; Lammer, Felicitas; Schroers, Roland; Hofer, Silvia; Bairey, Osnat; Braess, Jan; Meier-Stiegen, Anna Sofia; Stuhlmann, Reingard; Schmidt-Hieber, Martin; Hoffmann, Johannes; Zinngrebe, Bettina; Kaiser, Ulrich; Reimer, Peter; Möhle, Robert; Fix, Peter; Höffkes, Heinz-Gert; Langenkamp, Ulrich; Büschenfelde, Christian Meyer Zum; Hopfer, Olaf; Stoltefuß, Andrea; La Rosée, Paul; Blasberg, Henning; Jordan, Karin; Kaun, Stephan; Meurer, Anna; Unteroberdörster, Meike; von Brünneck, Ann-Christin; Capper, David; Heppner, Frank L; Chapuy, Björn; Janz, Martin; Schwartz, Stefan; Konietschke, Frank; Vajkoczy, Peter; Korfel, Agnieszka; Keller, Ulrich.

Eur J Cancer ; 196: 113436, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38008033

15.

Treatment Strategies and Prognostic Factors in Secondary Central Nervous System Lymphoma: A Multicenter Study of 124 Patients.

Treiber, Hannes; Nilius-Eliliwi, Verena; Seifert, Nicole; Vangala, Deepak; Wang, Meng; Seidel, Sabine; Mika, Thomas; Marschner, Dominik; Zeremski, Vanja; Wurm-Kuczera, Rebecca; Caillé, Leandra; Chapuy, Claudia I; Trümper, Lorenz; Fischer, Thomas; Altenbuchinger, Michael; Wulf, Gerald G; Illerhaus, Gerald; Dietrich, Sascha; Schroers, Roland; Chapuy, Björn.

Hemasphere ; 7(8): e926, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37492436

16.

European Association of Nuclear Medicine (EANM) Focus 4 consensus recommendations: molecular imaging and therapy in haematological tumours.

Nanni, Cristina; Kobe, Carsten; Baeßler, Bettina; Baues, Christian; Boellaard, Ronald; Borchmann, Peter; Buck, Andreas; Buvat, Irène; Chapuy, Björn; Cheson, Bruce D; Chrzan, Robert; Cottereau, Ann-Segolene; Dührsen, Ulrich; Eikenes, Live; Hutchings, Martin; Jurczak, Wojciech; Kraeber-Bodéré, Françoise; Lopci, Egesta; Luminari, Stefano; MacLennan, Steven; Mikhaeel, N George; Nijland, Marcel; Rodríguez-Otero, Paula; Treglia, Giorgio; Withofs, Nadia; Zamagni, Elena; Zinzani, Pier Luigi; Zijlstra, Josée M; Herrmann, Ken; Kunikowska, Jolanta.

Lancet Haematol ; 10(5): e367-e381, 2023 May.

Artigo em Inglês | MEDLINE | ID: mdl-37142345

17.

Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.

Demel, Uta M; Böger, Marlitt; Yousefian, Schayan; Grunert, Corinna; Zhang, Le; Hotz, Paul W; Gottschlich, Adrian; Köse, Hazal; Isaakidis, Konstandina; Vonficht, Dominik; Grünschläger, Florian; Rohleder, Elena; Wagner, Kristina; Dönig, Judith; Igl, Veronika; Brzezicha, Bernadette; Baumgartner, Francis; Habringer, Stefan; Löber, Jens; Chapuy, Björn; Weidinger, Carl; Kobold, Sebastian; Haas, Simon; Busse, Antonia B; Müller, Stefan; Wirth, Matthias; Schick, Markus; Keller, Ulrich.

J Clin Invest ; 132(9)2022 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-35499080

18.

Genetic alterations of the SUMO isopeptidase SENP6 drive lymphomagenesis and genetic instability in diffuse large B-cell lymphoma.

Schick, Markus; Zhang, Le; Maurer, Sabine; Maurer, Hans Carlo; Isaakaidis, Konstandina; Schneider, Lara; Patra, Upayan; Schunck, Kathrin; Rohleder, Elena; Hofstetter, Julia; Baluapuri, Apoorva; Scherger, Anna Katharina; Slotta-Huspenina, Julia; Hettler, Franziska; Weber, Julia; Engleitner, Thomas; Maresch, Roman; Slawska, Jolanta; Lewis, Richard; Istvanffy, Rouzanna; Habringer, Stefan; Steiger, Katja; Baiker, Armin; Oostendorp, Robert A J; Miething, Cornelius; Lenhof, Hans-Peter; Bassermann, Florian; Chapuy, Björn; Wirth, Matthias; Wolf, Elmar; Rad, Roland; Müller, Stefan; Keller, Ulrich.

Nat Commun ; 13(1): 281, 2022 01 12.

Artigo em Inglês | MEDLINE | ID: mdl-35022408

19.

The proteogenomic subtypes of acute myeloid leukemia.

Jayavelu, Ashok Kumar; Wolf, Sebastian; Buettner, Florian; Alexe, Gabriela; Häupl, Björn; Comoglio, Federico; Schneider, Constanze; Doebele, Carmen; Fuhrmann, Dominik C; Wagner, Sebastian; Donato, Elisa; Andresen, Carolin; Wilke, Anne C; Zindel, Alena; Jahn, Dominique; Splettstoesser, Bianca; Plessmann, Uwe; Münch, Silvia; Abou-El-Ardat, Khali; Makowka, Philipp; Acker, Fabian; Enssle, Julius C; Cremer, Anjali; Schnütgen, Frank; Kurrle, Nina; Chapuy, Björn; Löber, Jens; Hartmann, Sylvia; Wild, Peter J; Wittig, Ilka; Hübschmann, Daniel; Kaderali, Lars; Cox, Jürgen; Brüne, Bernhard; Röllig, Christoph; Thiede, Christian; Steffen, Björn; Bornhäuser, Martin; Trumpp, Andreas; Urlaub, Henning; Stegmaier, Kimberly; Serve, Hubert; Mann, Matthias; Oellerich, Thomas.

Cancer Cell ; 40(3): 301-317.e12, 2022 03 14.

Artigo em Inglês | MEDLINE | ID: mdl-35245447

20.

Patient-Specific Modeling of Diffuse Large B-Cell Lymphoma.

Thobe, Kirsten; Konrath, Fabian; Chapuy, Björn; Wolf, Jana.

Biomedicines ; 9(11)2021 Nov 10.

Artigo em Inglês | MEDLINE | ID: mdl-34829885

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