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Cornea ; 39(8): 1017-1019, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32282358

RESUMO

PURPOSE: This study compares the quality of donor corneal tissue stored in Optisol-GS and Cornea Cold. METHODS: Seventeen pairs of donor corneas were obtained from an eye bank. One of each pair was stored in Cornea Cold or Optisol-GS. Endothelial cell loss (ECL), central corneal thickness (CCT), and endothelial cell density (ECD) were measured at 7 and 21 days of storage. Qualitative metrics were evaluated by using a slit lamp. RESULTS: At days 7 and 21, there were no observed differences in qualitative corneal health of the samples. There were no statistical differences in the mean ECL at 7 and 21 days between the 2 groups (P = 0.07 and P = 0.50, respectively). At 7 days, the mean CCT was 644 ± 52 µm in the Cornea Cold group and 591 ± 64 µm in the Optisol-GS group (P = 0.001). At 21 days, CCT was 714 ± 55 µm in the Cornea Cold group and 708 ± 58 µm in the Optisol-GS group (P = 0.70). The mean ECD was not statistically different between the groups (P = 0.56 at 7 days and P = 0.14 at 21 days). CONCLUSIONS: Storage of corneal donor tissue in the Optisol-GS and Cornea Cold storage media resulted in statistically comparable ECL and ECD for up to 21 days. CCT was higher in Cornea Cold at 7 days, but this discrepancy disappeared at 21 days.


Assuntos
Córnea/cirurgia , Transplante de Córnea/métodos , Bancos de Olhos , Soluções para Preservação de Órgãos/farmacologia , Preservação de Órgãos/métodos , Doadores de Tecidos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Contagem de Células , Sobrevivência Celular , Criança , Pré-Escolar , Córnea/diagnóstico por imagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Microscopia com Lâmpada de Fenda , Adulto Jovem
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