Detalhe da pesquisa
1.
Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires.
Cell
; 166(6): 1471-1484.e18, 2016 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27610571
2.
An in vivo method for diversifying the functions of therapeutic antibodies.
Proc Natl Acad Sci U S A
; 118(10)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33658386
3.
Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models.
Proc Natl Acad Sci U S A
; 117(14): 7929-7940, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32209668
4.
The NAD-dependent deacetylase SIRT2 is required for programmed necrosis.
Nature
; 492(7428): 199-204, 2012 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23201684
5.
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.
Nature
; 469(7329): 250-4, 2011 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21160472
6.
CTCF-binding elements mediate control of V(D)J recombination.
Nature
; 477(7365): 424-30, 2011 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21909113
7.
Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination.
Mol Cell
; 31(5): 631-40, 2008 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18775323
8.
Elements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination.
Proc Natl Acad Sci U S A
; 107(51): 22207-12, 2010 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21123744
9.
Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome.
Proc Natl Acad Sci U S A
; 107(7): 3024-9, 2010 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20133615
10.
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice.
Proc Natl Acad Sci U S A
; 106(8): 2717-22, 2009 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19196992
11.
Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation.
Blood
; 113(13): 2965-75, 2009 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19126872
12.
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress.
Cell Metab
; 2(1): 67-76, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16054100
13.
Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation.
Biochem Soc Trans
; 37(Pt 3): 561-8, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19442251
14.
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Science
; 366(6470)2019 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31806786
15.
SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease.
Cell Rep
; 5(3): 654-665, 2013 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24210820
16.
The ARID family transcription factor bright is required for both hematopoietic stem cell and B lineage development.
Mol Cell Biol
; 31(5): 1041-53, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21199920
17.
Tissue-specific regulation of SIRT1 by calorie restriction.
Genes Dev
; 22(13): 1753-7, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18550784
18.
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally.
Mol Cell Biol
; 28(5): 1688-701, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-18180281
19.
Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells.
Proc Natl Acad Sci U S A
; 104(11): 4518-23, 2007 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-17360556
20.
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.
Mol Cell Biol
; 27(24): 8807-14, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17923681